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请大家建议,关于调控tRNA文章应投什么杂志。
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请大家建议,关于调控tRNA文章应投什么杂志。# Biology - 生物学
i*s
1
被laid off了,想回国2,3个星期。请问是不是这2,3个星期就不file claim了,然后
等回美国了再file。需要事先打电话给DOL吗?谢谢.
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c*e
2
I had a manuscript that is, basically, about a non-essential leucine tRNA
that could specifically regulate the activation of type three secretion
system 2 in Salmonella for virulence on transcriptional level, NOT in
translation level alone for sure. Also the tRNA mutant is sensitive to acid.
All phenotyps well correlated.
It seems that a tRNA has a role as small regulatory RNA. What kind of
journal could go, please advise. Thanks
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n*k
3
Any similar report before and how novel and well dissected? Big boss? tRNA/
small but non-miRNA/siRNA regulation is still very hot...If it is well
executed study and very novel, it could go as high as you could ever
imagine/like....there was a cell paper on tRNA as a potential oncogene
several ys ago but no follow up so far...I actually have noticed one miRNA-
like sncRNA of tRNA origin in my own research and considering how abundant
and extremely dramatic the change is, I suspect it would be very important
to my biology...

acid.

【在 c*******e 的大作中提到】
: I had a manuscript that is, basically, about a non-essential leucine tRNA
: that could specifically regulate the activation of type three secretion
: system 2 in Salmonella for virulence on transcriptional level, NOT in
: translation level alone for sure. Also the tRNA mutant is sensitive to acid.
: All phenotyps well correlated.
: It seems that a tRNA has a role as small regulatory RNA. What kind of
: journal could go, please advise. Thanks

avatar
s*y
4
RNA ?

acid.

【在 c*******e 的大作中提到】
: I had a manuscript that is, basically, about a non-essential leucine tRNA
: that could specifically regulate the activation of type three secretion
: system 2 in Salmonella for virulence on transcriptional level, NOT in
: translation level alone for sure. Also the tRNA mutant is sensitive to acid.
: All phenotyps well correlated.
: It seems that a tRNA has a role as small regulatory RNA. What kind of
: journal could go, please advise. Thanks

avatar
l*1
5
Science magazine?
but hopefully other team didn't already publish it:
likes:
//www.sciencemag.org/content/336/6089/1645
or
J Bacteriol.
//www.ncbi.nlm.nih.gov/pubmed/15060037

acid.

【在 c*******e 的大作中提到】
: I had a manuscript that is, basically, about a non-essential leucine tRNA
: that could specifically regulate the activation of type three secretion
: system 2 in Salmonella for virulence on transcriptional level, NOT in
: translation level alone for sure. Also the tRNA mutant is sensitive to acid.
: All phenotyps well correlated.
: It seems that a tRNA has a role as small regulatory RNA. What kind of
: journal could go, please advise. Thanks

avatar
c*b
6
Cell host & microbe
PLOS pathogens
看工作量,也看老板牛的程度
To neverthink
好像有一篇review介绍从snoRNA和tRNA来产生miRNA的,例子不多,但是有。
update:
http://www.ncbi.nlm.nih.gov/pubmed/21925378
我没记错
的话,第一篇snoRNA产生miRNA是发在PLOS genetics

acid.

【在 c*******e 的大作中提到】
: I had a manuscript that is, basically, about a non-essential leucine tRNA
: that could specifically regulate the activation of type three secretion
: system 2 in Salmonella for virulence on transcriptional level, NOT in
: translation level alone for sure. Also the tRNA mutant is sensitive to acid.
: All phenotyps well correlated.
: It seems that a tRNA has a role as small regulatory RNA. What kind of
: journal could go, please advise. Thanks

avatar
a*d
7
Molecular Cell
This journal really likes RNA study
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u*d
8
非常有意思的发现啊,tRNA居然可以调节转录

acid.

【在 c*******e 的大作中提到】
: I had a manuscript that is, basically, about a non-essential leucine tRNA
: that could specifically regulate the activation of type three secretion
: system 2 in Salmonella for virulence on transcriptional level, NOT in
: translation level alone for sure. Also the tRNA mutant is sensitive to acid.
: All phenotyps well correlated.
: It seems that a tRNA has a role as small regulatory RNA. What kind of
: journal could go, please advise. Thanks

avatar
p*c
9
Science
avatar
l*1
10
Plos Biology as another candidate
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j*p
11
Interesting, I think the level of the journal varies depend on how complete
your story is.

acid.

【在 c*******e 的大作中提到】
: I had a manuscript that is, basically, about a non-essential leucine tRNA
: that could specifically regulate the activation of type three secretion
: system 2 in Salmonella for virulence on transcriptional level, NOT in
: translation level alone for sure. Also the tRNA mutant is sensitive to acid.
: All phenotyps well correlated.
: It seems that a tRNA has a role as small regulatory RNA. What kind of
: journal could go, please advise. Thanks

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