V*t
2 楼
求发育生物学达人解释
比如 肝脏就长n千克,既不会变n+1千克,也不会n-1千克,怎么知道长到n就停止的?
为什么左手和右手几乎一样大?
为什么所有人的眼球体积都是a+/-b立方厘米,既不会大于上限,也不会低于下限?
为什么蚂蚁那么小,大象那么大?
全部都是一个hippo信号通路控制的?不可能吧。
有什么模型来解释这个吗
比如 肝脏就长n千克,既不会变n+1千克,也不会n-1千克,怎么知道长到n就停止的?
为什么左手和右手几乎一样大?
为什么所有人的眼球体积都是a+/-b立方厘米,既不会大于上限,也不会低于下限?
为什么蚂蚁那么小,大象那么大?
全部都是一个hippo信号通路控制的?不可能吧。
有什么模型来解释这个吗
r*k
4 楼
同问呀!
t*w
5 楼
你说这些有的是genetic上差异造成的,有的是正态分布的随机过程。
H*N
7 楼
This is actually a very interesting question. I don't think we know too much
about it. Circulating hormones such as growth hormone clearly play a role.
Intrinsic species-specificity (whatever it may be) must be involved as well.
The amazing thing is, even within a specific organ, the rations of
different parts/cell types are also well maintained. My feeling is that some
smart genetic analyses will be required to get a handle on this issue.
There also could be organ-specific mechanisms involved.
about it. Circulating hormones such as growth hormone clearly play a role.
Intrinsic species-specificity (whatever it may be) must be involved as well.
The amazing thing is, even within a specific organ, the rations of
different parts/cell types are also well maintained. My feeling is that some
smart genetic analyses will be required to get a handle on this issue.
There also could be organ-specific mechanisms involved.
i*0
8 楼
发发文章,骗骗grant还可以。
f*s
10 楼
搞清楚了肯定先用到XX增大和隆胸上了
V*t
11 楼
不可能吧 这么几十年来 发育生物学还没搞清楚这个问题???
much
.
well.
some
【在 H****N 的大作中提到】
: This is actually a very interesting question. I don't think we know too much
: about it. Circulating hormones such as growth hormone clearly play a role.
: Intrinsic species-specificity (whatever it may be) must be involved as well.
: The amazing thing is, even within a specific organ, the rations of
: different parts/cell types are also well maintained. My feeling is that some
: smart genetic analyses will be required to get a handle on this issue.
: There also could be organ-specific mechanisms involved.
much
.
well.
some
【在 H****N 的大作中提到】
: This is actually a very interesting question. I don't think we know too much
: about it. Circulating hormones such as growth hormone clearly play a role.
: Intrinsic species-specificity (whatever it may be) must be involved as well.
: The amazing thing is, even within a specific organ, the rations of
: different parts/cell types are also well maintained. My feeling is that some
: smart genetic analyses will be required to get a handle on this issue.
: There also could be organ-specific mechanisms involved.
z*u
19 楼
总觉得说一个pathway控制organ size 实在太简化了点。
换个角度看,发育的过程就是embryonic progenitor cell逐渐specify, restrict成为
lineage specific stem cell或者消失的过程。看看Hippo pathway是如何调控stem
cell的形成,特化应该会很有意思。
换个角度看,发育的过程就是embryonic progenitor cell逐渐specify, restrict成为
lineage specific stem cell或者消失的过程。看看Hippo pathway是如何调控stem
cell的形成,特化应该会很有意思。
相关阅读
求推荐CD44,CD24, CD133,ESA的抗体The best way to keep healthy in winter is to turn heater down探索生物学的问题澳门大学再招个人:biostatistician/bioinformatician好多faculty candidate还都是Mr呢浙大的特聘研究员是什么?请帮忙下篇 paper, thanks构建老鼠模型,署名问题求文献,有链接(包子酬谢)Retraction Note to: Pilot-Scale Demonstration of In Situ Chemical Reduction Technology at a FormerlyEchowuhao多多指教reviewer opportunity SOJ Materials Science & EngineeringCipher Green Energy 创业团队招人帖用实验室经费,买转行的学习资料Postodc position at Lieber Institute帮同事发 招生物信息主管又一个女卢刚!南卡大学枪击案,女PHD打死系主任老板,然后自 (转载)(got it) paper help各位浸淫lab这么多年,都见过什么样的实验室怪癖?