Review opportunity, Chemical Engineering Science# Immigration - 落地生根
c*o
1 楼
Email me at c*********[email protected]
With your name, brief background, email address.
Important: You need to register as a reviewer for Journal of Chemical
Engineering Science
I will recommend first three who contact me before tonight.
Title: Inter-particle coating variability in a continuous coater
Abstract:
The influence of particle axial motion on inter-particle coating variability
is studied in a rotating drum continuous coater. A mathematical framework
based on renewal theory is developed and an expression for inter-particle
coating variability is obtained that accounts for the variance in the
residence time of particles inside the coater. This model makes no
assumptions on the nature of the particle axial motion. Discrete element
method simulations have shown, however, that the particle axial motion can
be accurately modeled by a combination of advective and diffusive motion
characterized by an axial Peclet number. Using this advective-diffusive
model, it was found that in order to maintain an inter-particle coating
variability of less than 1%, typical of what might be needed for functional
pharmaceutical tablet coatings, a Peclet number of 20000 is required. Such a
large Peclet number would necessitate essentially plug flow for typical
continuous coater lengths of 1-2 m,
or coater lengths of at least 15 m for typical feed rates and spherical
particle diffusion coefficients.
With your name, brief background, email address.
Important: You need to register as a reviewer for Journal of Chemical
Engineering Science
I will recommend first three who contact me before tonight.
Title: Inter-particle coating variability in a continuous coater
Abstract:
The influence of particle axial motion on inter-particle coating variability
is studied in a rotating drum continuous coater. A mathematical framework
based on renewal theory is developed and an expression for inter-particle
coating variability is obtained that accounts for the variance in the
residence time of particles inside the coater. This model makes no
assumptions on the nature of the particle axial motion. Discrete element
method simulations have shown, however, that the particle axial motion can
be accurately modeled by a combination of advective and diffusive motion
characterized by an axial Peclet number. Using this advective-diffusive
model, it was found that in order to maintain an inter-particle coating
variability of less than 1%, typical of what might be needed for functional
pharmaceutical tablet coatings, a Peclet number of 20000 is required. Such a
large Peclet number would necessitate essentially plug flow for typical
continuous coater lengths of 1-2 m,
or coater lengths of at least 15 m for typical feed rates and spherical
particle diffusion coefficients.