想办Eb1A， 一片文章被 NewsRX 的 biotech business week 报道。内容如下：
Google 了一下NewsRx, 号称the world’s largest producer of health news
请问这个可以claim as media report 么
Drug Delivery Systems Studies from University of Maine Update Current Data
on Drug Delivery Systems (A comparison of the behavior of cholesterol, 7-
dehydrocholesterol and ergosterol in phospholipid membranes)
Published in Biotech Business Week, July 2nd, 2012
2012 JUL 2 (NewsRx) -- By a News Reporter-Staff News Editor at Biotech
Business Week -- Research findings on Drug Delivery Systems are discussed in
a new report. According to news originating from Orono, Maine, by NewsRx
correspondents, researchers stated "A molecular description of the effect of
incorporation of cholesterol (CHOL), 7-dehydrocholesterol (7DHC) and
ergosterol (ERGO) on the structure of DPPC or EggPC liposomes is provided.
Data obtained from ATR-IR spectroscopy, detergent solubility and zeta
potential measurements show that the insertion of the various sterols alters
the packing arrangement of the tails and headgroup of the PC lipids and may
lead to lipid domain formation."
Our news journalists obtained a quote from the research by the authors
from the University of Maine, "On a molecular basis, the differences in
lipid packing architecture are traced to differences between the ring and
tail structure of the three sterols and these differences in structure
produce different effects in DPPC liposomes in the gel phase and EggPC
liposomes in the fluid phase. Specifically, CHOL has a relatively flat and
linear structure and among the three sterols, shows the strongest molecular
interactions with DPPC and EggPC lipids. An extra double bond in the fused
ring of 7DHC hinders a tightly packing arrangement with DPPC lipids and
leads to less domain formation than CHOL whereas 7DHC clearly produces more
lipid domain formation in EggPC. ERGO produces similar structural changes to
7DHC in the tail and headgroup region of DPPC."
According to the news editors, the researchers concluded: "Nevertheless,
ERGO incorporation into DPPC liposomes produces more domain formation than
7DHC."
For more information on this research see: A comparison of the behavior
of cholesterol, 7-dehydrocholesterol and ergosterol in phospholipid
membranes. Biochimica Et Biophysica Acta-Biomembranes, 2012;1818(7):1673-
1681. Biochimica Et Biophysica Acta-Biomembranes can be contacted at:
Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands.
The news correspondents report that additional information may be
obtained from C.F. Chen, Univ Maine, Dept. of Chem, Orono, ME 04469, United
States.
