我觉得你们应该仔细研究一下下面这些文章,至于为什么我相信你们应该能理解的
Lundkvist GB, Sellix MT, Nygard M, Davis E, Straume M, Kristensson K, Block
GD. Clock gene expression during chronic inflammation induced by infection
with Trypanosoma brucei brucei in rats. J Biol Rhythms. 2010;25(2):92-102.
Nakamura TJ, Sellix MT, Kudo T, Nakao N, Yoshimura T, Ebihara S, Colwell CS,
Block GD. Influence of the estrous cycle on clock gene expression in
reproductive tissues: effects of fluctuating ovarian steroid hormone levels.
Steroids. 2010;75(3):203-12.
Nakamura TJ, Sellix MT, Menaker M, Block GD. Estrogen directly modulates
circadian rhythms of PER2 expression in the uterus. Am J Physiol Endocrinol
Metab. 2008;295(5):E1025-31.
Davidson AJ, Sellix MT, Daniel J, Yamazaki S, Menaker M, Block GD.
Chronic jet-lag increases mortality in aged mice. Curr Biol. 2006;16:R914-
R916.
Lundkvist GB, Kwak K, Davis E, Tei H, Block GD. A calcium flux is required
for circadian rhythm generation in mammalian pacemaker neurons. J
Neurosci. 2005;25:7682-7686.