No.这个是不是对waiver的批准有影响。 Either is fine. waiver时老板要出具的supporting letter是谁写呢,是项目科研老板,还是 行政上的老板 YOu need to talk to your Institute ISO, I remember NIH, EPA, FDA etc need to send a sponsor view, so your Institute need to send a sponsor view to DOS. So talk to your ISO first before your waiver.