In some states, such as TX, the law requires the candidates to submit the
transcript. But for some other states, the transcript request is totally
depends on the particular institution. I applied for several institutions in
the same state, some requests transcript but some does not.
I don't think research schools care about transcript. But teaching schools
may care about it once they request your transcript. A search committee
member even asked me why I got a low grade as B- of *** course over my interview.