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Re: 请教: A question in Molecular Evolution
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Re: 请教: A question in Molecular Evolution# Biology - 生物学
s*z
1
positive selection,u will expect to seea high ratio of non-synonymous
substitution to sys.
purifying selection gives u a low value of above ratio
increased rate theoretically affect sys. and non-sys. equally,this is
theoretical,but actually there is biased substitution
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s*z
2
there may be at least two possibilities
one is the change in the regulatory region of this gene,thus its expression
pattern is altered,though still the same protein.
the other could be the change of the transcription factor binding to this gene
and changed its expression pattern. but how is the change in the upstream
transcription factor,is it possibly protein level evolution?I dont know.
This may interest many of the researches,for they are the primary evolution
gene,not the secondary ones whos
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