http://biorxiv.org/content/biorxiv/early/2016/12/06/091678.full.pdf 结论摘要 Importantly, and in agreement with recently published reports [5-7], we found strictly no evidence of a double strand break of the DNA with NgAgo, and no editing of the mouse and human DNA despite an efficient delivery of NgAgo and the gDNA. We did not observe an editing event in over 100 mouse embryos injected with NgAgo, giving an editing efficiency of less than 1%, contradicting the results reported in Gao et al. 小鼠细胞和人类细胞全跪 reference 5 是protein &cell 中外联名文章 6 是cell research 的斑马鱼 7 Nature 打脸文 算上这个,4巴掌打韩主席的脸