t*s
2 楼
Amex Blue Cash preferred 6% Cashback+$150bonus超市专用信用卡
http://amex.co/Vlnu1C
不仅有welcome $150 bonus, 最重要的在于能享用6% cash back at supermarkets, 3
% cash back at gas stations and department stores。在超市花销比较大的,赶紧
下手吧。
• Earn $150 cash back after spending $1,000 in eligible purchases
in the first 3 months of Cardmembership
• Get 6% cash back at supermarkets, 3% cash back at gas stations
and department stores, and 1% cash back on all other purchases
• NO spend minimum, NO enrollment, and NO rotating rewards
categories
• 0% intro APR on purchases for 12 months, flexibility to pay over
time
http://amex.co/Vlnu1C
打开链接可以看到下面这个图样,是右边那张信用卡。
http://amex.co/Vlnu1C
不仅有welcome $150 bonus, 最重要的在于能享用6% cash back at supermarkets, 3
% cash back at gas stations and department stores。在超市花销比较大的,赶紧
下手吧。
• Earn $150 cash back after spending $1,000 in eligible purchases
in the first 3 months of Cardmembership
• Get 6% cash back at supermarkets, 3% cash back at gas stations
and department stores, and 1% cash back on all other purchases
• NO spend minimum, NO enrollment, and NO rotating rewards
categories
• 0% intro APR on purchases for 12 months, flexibility to pay over
time
http://amex.co/Vlnu1C
打开链接可以看到下面这个图样,是右边那张信用卡。
c*n
3 楼
http://www.j1ol.com/enterprise/interview/200905/3476751686.html
在药物全合成领域,K.C.Nicolaou被誉为登峰造极者,年轻的科学家对他顶礼膜拜,调
皮者称之为有机化学界的“西毒”。他以其出众的毅力、胆略和勇气合成了众多结构新
颖的复杂天然产物,每一个分子合成的精妙之处都体现了他的极深造诣,有些分子已成
为生物学研究中不可或缺的研究探针,这些分子的人工合成以及相应技术使得许多难以
进行的生物学研究成为可能。例如在组合化学中广泛应用的变频标记技术、系列抗炎、
抗菌和抗肿瘤药物的合成。
3月17日,《医药经济报》记者有幸在上海聆听了 Nicolaou的讲座并对其进行专访
,近距离感受大师风采。
凌晨捷报
1994年某天凌晨,睡梦中的Nicolaou被电话吵醒,是他的学生打来的。“请您务必
现在来实验室!”“我很困,有事不能等天亮吗?”对方的声音焦急而兴奋:“也许,
我们合成了taxol(紫杉醇)!”Nicolaou一下子睡意全无:“我5分钟内赶到!”
据说,2个小时后,他已经写好了论文寄出。15年后,再次回忆起这一幕,Ni
在药物全合成领域,K.C.Nicolaou被誉为登峰造极者,年轻的科学家对他顶礼膜拜,调
皮者称之为有机化学界的“西毒”。他以其出众的毅力、胆略和勇气合成了众多结构新
颖的复杂天然产物,每一个分子合成的精妙之处都体现了他的极深造诣,有些分子已成
为生物学研究中不可或缺的研究探针,这些分子的人工合成以及相应技术使得许多难以
进行的生物学研究成为可能。例如在组合化学中广泛应用的变频标记技术、系列抗炎、
抗菌和抗肿瘤药物的合成。
3月17日,《医药经济报》记者有幸在上海聆听了 Nicolaou的讲座并对其进行专访
,近距离感受大师风采。
凌晨捷报
1994年某天凌晨,睡梦中的Nicolaou被电话吵醒,是他的学生打来的。“请您务必
现在来实验室!”“我很困,有事不能等天亮吗?”对方的声音焦急而兴奋:“也许,
我们合成了taxol(紫杉醇)!”Nicolaou一下子睡意全无:“我5分钟内赶到!”
据说,2个小时后,他已经写好了论文寄出。15年后,再次回忆起这一幕,Ni
c*u
4 楼
国内写的人物采访我基本都得捏着鼻子才能读下去,读着一身鸡皮疙瘩,太寒碜人了..
..
..
h*e
5 楼
那个打电话给他的学生是杨震吗?
c*n
6 楼
..
w*h
7 楼
两个小时之后把文章写完投出。。。。
【在 c******n 的大作中提到】
: http://www.j1ol.com/enterprise/interview/200905/3476751686.html
: 在药物全合成领域,K.C.Nicolaou被誉为登峰造极者,年轻的科学家对他顶礼膜拜,调
: 皮者称之为有机化学界的“西毒”。他以其出众的毅力、胆略和勇气合成了众多结构新
: 颖的复杂天然产物,每一个分子合成的精妙之处都体现了他的极深造诣,有些分子已成
: 为生物学研究中不可或缺的研究探针,这些分子的人工合成以及相应技术使得许多难以
: 进行的生物学研究成为可能。例如在组合化学中广泛应用的变频标记技术、系列抗炎、
: 抗菌和抗肿瘤药物的合成。
: 3月17日,《医药经济报》记者有幸在上海聆听了 Nicolaou的讲座并对其进行专访
: ,近距离感受大师风采。
: 凌晨捷报
【在 c******n 的大作中提到】
: http://www.j1ol.com/enterprise/interview/200905/3476751686.html
: 在药物全合成领域,K.C.Nicolaou被誉为登峰造极者,年轻的科学家对他顶礼膜拜,调
: 皮者称之为有机化学界的“西毒”。他以其出众的毅力、胆略和勇气合成了众多结构新
: 颖的复杂天然产物,每一个分子合成的精妙之处都体现了他的极深造诣,有些分子已成
: 为生物学研究中不可或缺的研究探针,这些分子的人工合成以及相应技术使得许多难以
: 进行的生物学研究成为可能。例如在组合化学中广泛应用的变频标记技术、系列抗炎、
: 抗菌和抗肿瘤药物的合成。
: 3月17日,《医药经济报》记者有幸在上海聆听了 Nicolaou的讲座并对其进行专访
: ,近距离感受大师风采。
: 凌晨捷报
B*1
10 楼
I heard that in the old days, Boger wrote a synthetic paper first. Then he
gave the draft to a postdoc or student and asked him or her to fill in the
blank of yields (better be 99%).
gave the draft to a postdoc or student and asked him or her to fill in the
blank of yields (better be 99%).
j*y
11 楼
有没有人统计一下KC自出道以来压榨了多少老中的血汗才有今日的名声
【在 c******n 的大作中提到】
: http://www.j1ol.com/enterprise/interview/200905/3476751686.html
: 在药物全合成领域,K.C.Nicolaou被誉为登峰造极者,年轻的科学家对他顶礼膜拜,调
: 皮者称之为有机化学界的“西毒”。他以其出众的毅力、胆略和勇气合成了众多结构新
: 颖的复杂天然产物,每一个分子合成的精妙之处都体现了他的极深造诣,有些分子已成
: 为生物学研究中不可或缺的研究探针,这些分子的人工合成以及相应技术使得许多难以
: 进行的生物学研究成为可能。例如在组合化学中广泛应用的变频标记技术、系列抗炎、
: 抗菌和抗肿瘤药物的合成。
: 3月17日,《医药经济报》记者有幸在上海聆听了 Nicolaou的讲座并对其进行专访
: ,近距离感受大师风采。
: 凌晨捷报
【在 c******n 的大作中提到】
: http://www.j1ol.com/enterprise/interview/200905/3476751686.html
: 在药物全合成领域,K.C.Nicolaou被誉为登峰造极者,年轻的科学家对他顶礼膜拜,调
: 皮者称之为有机化学界的“西毒”。他以其出众的毅力、胆略和勇气合成了众多结构新
: 颖的复杂天然产物,每一个分子合成的精妙之处都体现了他的极深造诣,有些分子已成
: 为生物学研究中不可或缺的研究探针,这些分子的人工合成以及相应技术使得许多难以
: 进行的生物学研究成为可能。例如在组合化学中广泛应用的变频标记技术、系列抗炎、
: 抗菌和抗肿瘤药物的合成。
: 3月17日,《医药经济报》记者有幸在上海聆听了 Nicolaou的讲座并对其进行专访
: ,近距离感受大师风采。
: 凌晨捷报
s*s
12 楼
此老兄一直对没拿炸药奖耿耿于怀
O*f
13 楼
KC is in the candidate list, but so far European committee chemists still
think KC's achievements on synthesis are the outcome of piling up dollars
over dollars and men over men. Well, personally, I don't agree to such
comment. Hopefully, 炸药奖 should give another chance to total synthesis
chemists in the near future.
【在 s********s 的大作中提到】
: 此老兄一直对没拿炸药奖耿耿于怀
think KC's achievements on synthesis are the outcome of piling up dollars
over dollars and men over men. Well, personally, I don't agree to such
comment. Hopefully, 炸药奖 should give another chance to total synthesis
chemists in the near future.
【在 s********s 的大作中提到】
: 此老兄一直对没拿炸药奖耿耿于怀
a*n
14 楼
Nice comment.
IMHO THE ERA has gone to the toilet and it may never come back.
【在 O*******f 的大作中提到】
: KC is in the candidate list, but so far European committee chemists still
: think KC's achievements on synthesis are the outcome of piling up dollars
: over dollars and men over men. Well, personally, I don't agree to such
: comment. Hopefully, 炸药奖 should give another chance to total synthesis
: chemists in the near future.
IMHO THE ERA has gone to the toilet and it may never come back.
【在 O*******f 的大作中提到】
: KC is in the candidate list, but so far European committee chemists still
: think KC's achievements on synthesis are the outcome of piling up dollars
: over dollars and men over men. Well, personally, I don't agree to such
: comment. Hopefully, 炸药奖 should give another chance to total synthesis
: chemists in the near future.
s*c
15 楼
Has 炸药奖 ever be given to a piling-up style total synthesis
chemists in the past? Do not tell me EJ. He got it because of
retrosynthesis
chemists in the past? Do not tell me EJ. He got it because of
retrosynthesis
L*L
16 楼
A hahahaha. so funny.
O*f
17 楼
only few people focusing on chemical synthesis (especially total synthesis)
won the prize. I don't want to comment on the giants, such as RBW, EJC, Sir
RR, KBS and 野依良治. What I want to say is that KCN currently is one of the
few best of the best synthetic chemists. If other synthetic chemist(s)
would be the prize winner, but not KCN,it should be a shame.
overall, as a trend, it seemed the prize would not prefer synthetic chemists
, whom, I think, are undervalued by the prize committee. Synthesis
【在 s******c 的大作中提到】
: Has 炸药奖 ever be given to a piling-up style total synthesis
: chemists in the past? Do not tell me EJ. He got it because of
: retrosynthesis
won the prize. I don't want to comment on the giants, such as RBW, EJC, Sir
RR, KBS and 野依良治. What I want to say is that KCN currently is one of the
few best of the best synthetic chemists. If other synthetic chemist(s)
would be the prize winner, but not KCN,it should be a shame.
overall, as a trend, it seemed the prize would not prefer synthetic chemists
, whom, I think, are undervalued by the prize committee. Synthesis
【在 s******c 的大作中提到】
: Has 炸药奖 ever be given to a piling-up style total synthesis
: chemists in the past? Do not tell me EJ. He got it because of
: retrosynthesis
O*f
18 楼
About EJC's achievements, I still think his retrosynthesis methodology is
honnored because of its very successful applications in the SYNTHESIS,
especially total synthesis, by himself and other chemists.
Accordingly, I would show you another example, which I ever thought (允许排
砖). Suppose we have atomic tweezers that can hold single or a few atoms at
a time (although now it is not pratically available yet), and we may carry
on the synthesis of any reasonable molecule by attaching one atom with
an
【在 s******c 的大作中提到】
: Has 炸药奖 ever be given to a piling-up style total synthesis
: chemists in the past? Do not tell me EJ. He got it because of
: retrosynthesis
honnored because of its very successful applications in the SYNTHESIS,
especially total synthesis, by himself and other chemists.
Accordingly, I would show you another example, which I ever thought (允许排
砖). Suppose we have atomic tweezers that can hold single or a few atoms at
a time (although now it is not pratically available yet), and we may carry
on the synthesis of any reasonable molecule by attaching one atom with
an
【在 s******c 的大作中提到】
: Has 炸药奖 ever be given to a piling-up style total synthesis
: chemists in the past? Do not tell me EJ. He got it because of
: retrosynthesis
s*h
19 楼
我就是K饭啊。。。你们K黑来拍砖吧。。。
)
Sir
the
chemists
【在 O*******f 的大作中提到】
: only few people focusing on chemical synthesis (especially total synthesis)
: won the prize. I don't want to comment on the giants, such as RBW, EJC, Sir
: RR, KBS and 野依良治. What I want to say is that KCN currently is one of the
: few best of the best synthetic chemists. If other synthetic chemist(s)
: would be the prize winner, but not KCN,it should be a shame.
: overall, as a trend, it seemed the prize would not prefer synthetic chemists
: , whom, I think, are undervalued by the prize committee. Synthesis
)
Sir
the
chemists
【在 O*******f 的大作中提到】
: only few people focusing on chemical synthesis (especially total synthesis)
: won the prize. I don't want to comment on the giants, such as RBW, EJC, Sir
: RR, KBS and 野依良治. What I want to say is that KCN currently is one of the
: few best of the best synthetic chemists. If other synthetic chemist(s)
: would be the prize winner, but not KCN,it should be a shame.
: overall, as a trend, it seemed the prize would not prefer synthetic chemists
: , whom, I think, are undervalued by the prize committee. Synthesis
O*f
20 楼
再重申一遍,炸药奖虽然口口声声说鼓励新的化学方法学研究,但从来都是偏重实际应
用的(比如RCM)。没有广泛应用前途的方法学是不会得奖的。既然看重实际应用,那
么有机合成(含全合成)已经在诸多方面有力有益得影响了人类社会,就应该获奖。虽
然不明说出来,但炸药奖委员会是有充分理由固守他们的个人偏见的。
有兴趣的童鞋可以看评论炸药奖的书。有个美国女记者的书(有中译版)很有影响力,
举出了很多统计学数据。
希望这两年的炸药奖能honor一下合成化学,看起来很像10年一轮回的样子。
用的(比如RCM)。没有广泛应用前途的方法学是不会得奖的。既然看重实际应用,那
么有机合成(含全合成)已经在诸多方面有力有益得影响了人类社会,就应该获奖。虽
然不明说出来,但炸药奖委员会是有充分理由固守他们的个人偏见的。
有兴趣的童鞋可以看评论炸药奖的书。有个美国女记者的书(有中译版)很有影响力,
举出了很多统计学数据。
希望这两年的炸药奖能honor一下合成化学,看起来很像10年一轮回的样子。
s*h
21 楼
童鞋啊,你看到现在广大下岗在家的合成WSN还不够辛酸啊,非要再伤口上撒一把盐?
【在 O*******f 的大作中提到】
: 再重申一遍,炸药奖虽然口口声声说鼓励新的化学方法学研究,但从来都是偏重实际应
: 用的(比如RCM)。没有广泛应用前途的方法学是不会得奖的。既然看重实际应用,那
: 么有机合成(含全合成)已经在诸多方面有力有益得影响了人类社会,就应该获奖。虽
: 然不明说出来,但炸药奖委员会是有充分理由固守他们的个人偏见的。
: 有兴趣的童鞋可以看评论炸药奖的书。有个美国女记者的书(有中译版)很有影响力,
: 举出了很多统计学数据。
: 希望这两年的炸药奖能honor一下合成化学,看起来很像10年一轮回的样子。
【在 O*******f 的大作中提到】
: 再重申一遍,炸药奖虽然口口声声说鼓励新的化学方法学研究,但从来都是偏重实际应
: 用的(比如RCM)。没有广泛应用前途的方法学是不会得奖的。既然看重实际应用,那
: 么有机合成(含全合成)已经在诸多方面有力有益得影响了人类社会,就应该获奖。虽
: 然不明说出来,但炸药奖委员会是有充分理由固守他们的个人偏见的。
: 有兴趣的童鞋可以看评论炸药奖的书。有个美国女记者的书(有中译版)很有影响力,
: 举出了很多统计学数据。
: 希望这两年的炸药奖能honor一下合成化学,看起来很像10年一轮回的样子。
s*7
22 楼
http://www.mitbbs.com/article_t/Science/31151447.html
..
【在 c*******u 的大作中提到】
: 国内写的人物采访我基本都得捏着鼻子才能读下去,读着一身鸡皮疙瘩,太寒碜人了..
: ..
..
【在 c*******u 的大作中提到】
: 国内写的人物采访我基本都得捏着鼻子才能读下去,读着一身鸡皮疙瘩,太寒碜人了..
: ..
N*n
26 楼
全合成要再想拿奖的可能性小于0.0000000000000000000000001%
【在 O*******f 的大作中提到】
: 再重申一遍,炸药奖虽然口口声声说鼓励新的化学方法学研究,但从来都是偏重实际应
: 用的(比如RCM)。没有广泛应用前途的方法学是不会得奖的。既然看重实际应用,那
: 么有机合成(含全合成)已经在诸多方面有力有益得影响了人类社会,就应该获奖。虽
: 然不明说出来,但炸药奖委员会是有充分理由固守他们的个人偏见的。
: 有兴趣的童鞋可以看评论炸药奖的书。有个美国女记者的书(有中译版)很有影响力,
: 举出了很多统计学数据。
: 希望这两年的炸药奖能honor一下合成化学,看起来很像10年一轮回的样子。
【在 O*******f 的大作中提到】
: 再重申一遍,炸药奖虽然口口声声说鼓励新的化学方法学研究,但从来都是偏重实际应
: 用的(比如RCM)。没有广泛应用前途的方法学是不会得奖的。既然看重实际应用,那
: 么有机合成(含全合成)已经在诸多方面有力有益得影响了人类社会,就应该获奖。虽
: 然不明说出来,但炸药奖委员会是有充分理由固守他们的个人偏见的。
: 有兴趣的童鞋可以看评论炸药奖的书。有个美国女记者的书(有中译版)很有影响力,
: 举出了很多统计学数据。
: 希望这两年的炸药奖能honor一下合成化学,看起来很像10年一轮回的样子。
a*i
29 楼
我才注意到老K缩写是KCN.艹
)
Sir
the
chemists
【在 O*******f 的大作中提到】
: only few people focusing on chemical synthesis (especially total synthesis)
: won the prize. I don't want to comment on the giants, such as RBW, EJC, Sir
: RR, KBS and 野依良治. What I want to say is that KCN currently is one of the
: few best of the best synthetic chemists. If other synthetic chemist(s)
: would be the prize winner, but not KCN,it should be a shame.
: overall, as a trend, it seemed the prize would not prefer synthetic chemists
: , whom, I think, are undervalued by the prize committee. Synthesis
)
Sir
the
chemists
【在 O*******f 的大作中提到】
: only few people focusing on chemical synthesis (especially total synthesis)
: won the prize. I don't want to comment on the giants, such as RBW, EJC, Sir
: RR, KBS and 野依良治. What I want to say is that KCN currently is one of the
: few best of the best synthetic chemists. If other synthetic chemist(s)
: would be the prize winner, but not KCN,it should be a shame.
: overall, as a trend, it seemed the prize would not prefer synthetic chemists
: , whom, I think, are undervalued by the prize committee. Synthesis
a*e
30 楼
taxol是Holton先合成的吧,
epothilone是Danishefsky先合成的.
epothilone是Danishefsky先合成的.
e*l
32 楼
不知道评奖委员会有没有做过全合成的,合成一个复杂的分子,巧妙的构思是非常重要
的吧,再说不管
搞啥研究,堆人堆钱,基本上都是必须的,到了KCN这儿,好像这就成了罪过似的。
still
dollars
【在 O*******f 的大作中提到】
: KC is in the candidate list, but so far European committee chemists still
: think KC's achievements on synthesis are the outcome of piling up dollars
: over dollars and men over men. Well, personally, I don't agree to such
: comment. Hopefully, 炸药奖 should give another chance to total synthesis
: chemists in the near future.
的吧,再说不管
搞啥研究,堆人堆钱,基本上都是必须的,到了KCN这儿,好像这就成了罪过似的。
still
dollars
【在 O*******f 的大作中提到】
: KC is in the candidate list, but so far European committee chemists still
: think KC's achievements on synthesis are the outcome of piling up dollars
: over dollars and men over men. Well, personally, I don't agree to such
: comment. Hopefully, 炸药奖 should give another chance to total synthesis
: chemists in the near future.
r*d
34 楼
totally disagree
)
Sir
the
chemists
【在 O*******f 的大作中提到】
: only few people focusing on chemical synthesis (especially total synthesis)
: won the prize. I don't want to comment on the giants, such as RBW, EJC, Sir
: RR, KBS and 野依良治. What I want to say is that KCN currently is one of the
: few best of the best synthetic chemists. If other synthetic chemist(s)
: would be the prize winner, but not KCN,it should be a shame.
: overall, as a trend, it seemed the prize would not prefer synthetic chemists
: , whom, I think, are undervalued by the prize committee. Synthesis
)
Sir
the
chemists
【在 O*******f 的大作中提到】
: only few people focusing on chemical synthesis (especially total synthesis)
: won the prize. I don't want to comment on the giants, such as RBW, EJC, Sir
: RR, KBS and 野依良治. What I want to say is that KCN currently is one of the
: few best of the best synthetic chemists. If other synthetic chemist(s)
: would be the prize winner, but not KCN,it should be a shame.
: overall, as a trend, it seemed the prize would not prefer synthetic chemists
: , whom, I think, are undervalued by the prize committee. Synthesis
N*n
38 楼
"Synthesis is and should be always the center of chemistry."
lol
30年前有可能有人这么说,现在说这话会被认为是疯子
)
Sir
the
chemists
【在 O*******f 的大作中提到】
: only few people focusing on chemical synthesis (especially total synthesis)
: won the prize. I don't want to comment on the giants, such as RBW, EJC, Sir
: RR, KBS and 野依良治. What I want to say is that KCN currently is one of the
: few best of the best synthetic chemists. If other synthetic chemist(s)
: would be the prize winner, but not KCN,it should be a shame.
: overall, as a trend, it seemed the prize would not prefer synthetic chemists
: , whom, I think, are undervalued by the prize committee. Synthesis
lol
30年前有可能有人这么说,现在说这话会被认为是疯子
)
Sir
the
chemists
【在 O*******f 的大作中提到】
: only few people focusing on chemical synthesis (especially total synthesis)
: won the prize. I don't want to comment on the giants, such as RBW, EJC, Sir
: RR, KBS and 野依良治. What I want to say is that KCN currently is one of the
: few best of the best synthetic chemists. If other synthetic chemist(s)
: would be the prize winner, but not KCN,it should be a shame.
: overall, as a trend, it seemed the prize would not prefer synthetic chemists
: , whom, I think, are undervalued by the prize committee. Synthesis
c*n
43 楼
全是乱码, 说啥呢
批?
??
批?
??
e*a
44 楼
Total synthesis went to a dead end decades ago. Recently, total synthesis
equals to extensive routine work and extraordinary amount of labor work. No
new concepts or knowledge is created in this field. Total synthesis itself
is just a combination of multiple reactions to transform some simple
compounds to complicated ones and the route is designed by retrosynthesis (
which was awarded to EJC). For this reason, I believe Nobel prize committee
will not give prizes to anyone for his contributio
【在 O*******f 的大作中提到】
: only few people focusing on chemical synthesis (especially total synthesis)
: won the prize. I don't want to comment on the giants, such as RBW, EJC, Sir
: RR, KBS and 野依良治. What I want to say is that KCN currently is one of the
: few best of the best synthetic chemists. If other synthetic chemist(s)
: would be the prize winner, but not KCN,it should be a shame.
: overall, as a trend, it seemed the prize would not prefer synthetic chemists
: , whom, I think, are undervalued by the prize committee. Synthesis
equals to extensive routine work and extraordinary amount of labor work. No
new concepts or knowledge is created in this field. Total synthesis itself
is just a combination of multiple reactions to transform some simple
compounds to complicated ones and the route is designed by retrosynthesis (
which was awarded to EJC). For this reason, I believe Nobel prize committee
will not give prizes to anyone for his contributio
【在 O*******f 的大作中提到】
: only few people focusing on chemical synthesis (especially total synthesis)
: won the prize. I don't want to comment on the giants, such as RBW, EJC, Sir
: RR, KBS and 野依良治. What I want to say is that KCN currently is one of the
: few best of the best synthetic chemists. If other synthetic chemist(s)
: would be the prize winner, but not KCN,it should be a shame.
: overall, as a trend, it seemed the prize would not prefer synthetic chemists
: , whom, I think, are undervalued by the prize committee. Synthesis
z*g
46 楼
看投稿日期和接受日期很容易知道
KCN在得知holton投稿后一段时间才给Nature投的稿,但Nature发表的速度惊人的快
KCN最后接侧链还是用的holton的技术,不然差的更多;
holton做紫杉烷类合成研究很多年,因此KCN输的也不能算丢人
但是KCN后来表现实在太差,包括在Angiew的review到处宣传是他先做出来的
还暗示holton先做出来的消息是“rumor”
由于惧怕KCN-corey派系,大部分人不敢多说,但也有人看不惯,
比如Carey就在他的advanced organic chemisty里公开宣称是holton先做出来
【在 C******d 的大作中提到】
: 据说是Holton先完成,然后投JACS, 被KC以种种手段压了一段时间,等自己做完投了稿
: 才把holton的放出去。holton做得比KC漂亮多了,不然KC发个屁nature。而且挣大钱的
: 不还是holton
KCN在得知holton投稿后一段时间才给Nature投的稿,但Nature发表的速度惊人的快
KCN最后接侧链还是用的holton的技术,不然差的更多;
holton做紫杉烷类合成研究很多年,因此KCN输的也不能算丢人
但是KCN后来表现实在太差,包括在Angiew的review到处宣传是他先做出来的
还暗示holton先做出来的消息是“rumor”
由于惧怕KCN-corey派系,大部分人不敢多说,但也有人看不惯,
比如Carey就在他的advanced organic chemisty里公开宣称是holton先做出来
【在 C******d 的大作中提到】
: 据说是Holton先完成,然后投JACS, 被KC以种种手段压了一段时间,等自己做完投了稿
: 才把holton的放出去。holton做得比KC漂亮多了,不然KC发个屁nature。而且挣大钱的
: 不还是holton
k*m
47 楼
如果全合成dead了,那有机合成就dead了。任何方法学不能用于全合成基本上就是废纸
。
。
k*m
49 楼
不能用于合成出有用的分子,就是废纸,呵呵。
S*r
50 楼
嗯,holton是93年末投的,The way of synthesis上写的明白
【在 z*******g 的大作中提到】
: 看投稿日期和接受日期很容易知道
: KCN在得知holton投稿后一段时间才给Nature投的稿,但Nature发表的速度惊人的快
: KCN最后接侧链还是用的holton的技术,不然差的更多;
: holton做紫杉烷类合成研究很多年,因此KCN输的也不能算丢人
: 但是KCN后来表现实在太差,包括在Angiew的review到处宣传是他先做出来的
: 还暗示holton先做出来的消息是“rumor”
: 由于惧怕KCN-corey派系,大部分人不敢多说,但也有人看不惯,
: 比如Carey就在他的advanced organic chemisty里公开宣称是holton先做出来
【在 z*******g 的大作中提到】
: 看投稿日期和接受日期很容易知道
: KCN在得知holton投稿后一段时间才给Nature投的稿,但Nature发表的速度惊人的快
: KCN最后接侧链还是用的holton的技术,不然差的更多;
: holton做紫杉烷类合成研究很多年,因此KCN输的也不能算丢人
: 但是KCN后来表现实在太差,包括在Angiew的review到处宣传是他先做出来的
: 还暗示holton先做出来的消息是“rumor”
: 由于惧怕KCN-corey派系,大部分人不敢多说,但也有人看不惯,
: 比如Carey就在他的advanced organic chemisty里公开宣称是holton先做出来
e*l
51 楼
有些得诺奖的研究,像那个C60的工作,好像也没什么重大的应用吧(俺不是内行,说
错了请大牛指
教)。有相当一部分方法学的发现,都是全合成的side project,至少从这一点看,全
合成还是有
积极意义的,当然这年头,这种发现貌似是越来越少了。其实给不给奖,跟咱也没啥关
系,全合成的
文章,读起来有趣,也就够了。
synthesis
work. No
itself
retrosynthesis (
committee
synthesis",
(such as
【在 e****a 的大作中提到】
: Total synthesis went to a dead end decades ago. Recently, total synthesis
: equals to extensive routine work and extraordinary amount of labor work. No
: new concepts or knowledge is created in this field. Total synthesis itself
: is just a combination of multiple reactions to transform some simple
: compounds to complicated ones and the route is designed by retrosynthesis (
: which was awarded to EJC). For this reason, I believe Nobel prize committee
: will not give prizes to anyone for his contributio
错了请大牛指
教)。有相当一部分方法学的发现,都是全合成的side project,至少从这一点看,全
合成还是有
积极意义的,当然这年头,这种发现貌似是越来越少了。其实给不给奖,跟咱也没啥关
系,全合成的
文章,读起来有趣,也就够了。
synthesis
work. No
itself
retrosynthesis (
committee
synthesis",
(such as
【在 e****a 的大作中提到】
: Total synthesis went to a dead end decades ago. Recently, total synthesis
: equals to extensive routine work and extraordinary amount of labor work. No
: new concepts or knowledge is created in this field. Total synthesis itself
: is just a combination of multiple reactions to transform some simple
: compounds to complicated ones and the route is designed by retrosynthesis (
: which was awarded to EJC). For this reason, I believe Nobel prize committee
: will not give prizes to anyone for his contributio
l*n
52 楼
"据说,2个小时后,他已经写好了论文寄出。"
if this is true, then he is not a qualified scientist
if this is true, then he is not a qualified scientist
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