分三段贴出拙著序言中几段，附带译文 （3）# ChineseMed - 中医
J*1
1 楼
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The book primarily is focused on the interface of chemistry/biology and
molecular biology and comprehensively summarizes the recent cutting-edge
research advances in the field of cancer inhibitors (included extracts and
compounds) from Chinese natural medicines. To underline how Chinese natural
medicines research continues to make predominant contributions in the domain
of discovery and development of novel cancer inhibitors, the book
highlights the scientific evidences of 238 Chinese herbs in the eight major
aspects: (i) advanced discoveries of cancer inhibitors from Chinese natural
medicines; (ii) in vitro and in vivo inhibitory effects against different
types of cancer cells, such as their anti-proliferative, antigrowth,
antimetastatic, antitumorigenic and antioxidant properties; (iii) modern
exploration of suppression mechanisms; (iv) synergistic activities in the
combination of current cancer therapies with the inhibitors; (v) reversal
advantage of the inhibitors against drug-resistance; (vi) structural
modification to derive more important molecules for drug development; (vii)
formulation researches on nanocapsules/microparticals, immunotoxin/antibody-
drug conjugate, and metal complex; and (viii) clinical trials and practices
of the herb extracts and/or promising inhibitors (compounds) derived from
Chinese natural medicines.
本书着重于化学/生物学和分子生物学的界面，全面总结了近几十年来天然中草药(包括
提取物和化合物)抗癌抑瘤领域中的前沿研究进展。为了叙述天然中草药是如何在发现
和开发新型抗癌药物的研究领域中，连续地贡献出不错的表现，本书突出了238种中草
药在8个主要方面的科学证据: (i) 从天然中草药中发现癌症抑制剂和活性成分 （包
括小分子和大分子）; (ii) 对不同类型的癌细胞的体外和体内抑制作用（抑瘤谱），
譬如抗增殖、抗生长、抗转移、抗致肿瘤和抗氧化活性作用; (iii) 对其抑瘤作用机
制进行现代化探索 （分子生物学层面）; (iv) 其抑瘤剂与当前癌症治疗法（化疗与
放疗）相结合的协同作用; (v) 其逆转耐药性化疗药物的优势; (vi) 结构修饰与改
造，为药物开发提供更重要更有效的分子（抑瘤剂）; (vii) 新型制剂研究（纳米 与
微米剂型，抗毒素与抗体共轭药物，和金属络合药物）; (viii) 有良好前景的中药精
提物和抑瘤剂 (化合物)的临床试验和实践。
（这些科研成果饱含进一步开发有潜力的新药先导化合物和设计新药的重要信息）
==
Consequently, the book brings readers comprehensive and illuminating
insights into cancer inhibitors from Chinese natural medicines. The 238
Chinese herbs have been categorized into 14 Chapters in the book according
to their main functions in Chinese medicine. For most of the selected herbs,
the research data has been collected up to October, 2015, from the latest
challenges in the anticancer approaches。
因此，通过这本书可以使读者对天然中草药的抗癌抑瘤剂及其活性有综合性的了解。这
238种中草药按其原先主要功能被分为14个章节。所选定的大多数中草药的抗癌研究数
据及成果收集到2015年10月。（实际上，到2015 年底，少数到2016年3月）
The book primarily is focused on the interface of chemistry/biology and
molecular biology and comprehensively summarizes the recent cutting-edge
research advances in the field of cancer inhibitors (included extracts and
compounds) from Chinese natural medicines. To underline how Chinese natural
medicines research continues to make predominant contributions in the domain
of discovery and development of novel cancer inhibitors, the book
highlights the scientific evidences of 238 Chinese herbs in the eight major
aspects: (i) advanced discoveries of cancer inhibitors from Chinese natural
medicines; (ii) in vitro and in vivo inhibitory effects against different
types of cancer cells, such as their anti-proliferative, antigrowth,
antimetastatic, antitumorigenic and antioxidant properties; (iii) modern
exploration of suppression mechanisms; (iv) synergistic activities in the
combination of current cancer therapies with the inhibitors; (v) reversal
advantage of the inhibitors against drug-resistance; (vi) structural
modification to derive more important molecules for drug development; (vii)
formulation researches on nanocapsules/microparticals, immunotoxin/antibody-
drug conjugate, and metal complex; and (viii) clinical trials and practices
of the herb extracts and/or promising inhibitors (compounds) derived from
Chinese natural medicines.
本书着重于化学/生物学和分子生物学的界面，全面总结了近几十年来天然中草药(包括
提取物和化合物)抗癌抑瘤领域中的前沿研究进展。为了叙述天然中草药是如何在发现
和开发新型抗癌药物的研究领域中，连续地贡献出不错的表现，本书突出了238种中草
药在8个主要方面的科学证据: (i) 从天然中草药中发现癌症抑制剂和活性成分 （包
括小分子和大分子）; (ii) 对不同类型的癌细胞的体外和体内抑制作用（抑瘤谱），
譬如抗增殖、抗生长、抗转移、抗致肿瘤和抗氧化活性作用; (iii) 对其抑瘤作用机
制进行现代化探索 （分子生物学层面）; (iv) 其抑瘤剂与当前癌症治疗法（化疗与
放疗）相结合的协同作用; (v) 其逆转耐药性化疗药物的优势; (vi) 结构修饰与改
造，为药物开发提供更重要更有效的分子（抑瘤剂）; (vii) 新型制剂研究（纳米 与
微米剂型，抗毒素与抗体共轭药物，和金属络合药物）; (viii) 有良好前景的中药精
提物和抑瘤剂 (化合物)的临床试验和实践。
（这些科研成果饱含进一步开发有潜力的新药先导化合物和设计新药的重要信息）
==
Consequently, the book brings readers comprehensive and illuminating
insights into cancer inhibitors from Chinese natural medicines. The 238
Chinese herbs have been categorized into 14 Chapters in the book according
to their main functions in Chinese medicine. For most of the selected herbs,
the research data has been collected up to October, 2015, from the latest
challenges in the anticancer approaches。
因此，通过这本书可以使读者对天然中草药的抗癌抑瘤剂及其活性有综合性的了解。这
238种中草药按其原先主要功能被分为14个章节。所选定的大多数中草药的抗癌研究数
据及成果收集到2015年10月。（实际上，到2015 年底，少数到2016年3月）