r*t
2 楼
【 以下文字转载自 Biology 讨论区 】
发信人: xiaomingxiao (xiaomingxiao), 信区: Biology
标 题: 气功大师发表的SCI，牛啊
发信站: BBS 未名空间站 (Mon Aug 5 15:48:20 2013, 美东)
Cell Physiol Biochem. 2013;31(1):113-22. doi: 10.1159/000343354. Epub 2013
Jan 25.
External Qi of Yan Xin Qigong inhibits activation of Akt, Erk1/2 and NF-
312;B and induces cell cycle arrest and apoptosis in colorectal cancer cells.
Yan X, Shen H, Jiang H, Hu D, Wang J, Wu X.
Background/Aims: Colorectal cancer (CRC) is the second leading cause of
cancer death in the Western countries. Novel approaches of treatment are
needed for CRC. The purpose of the present study was to investigate
cytotoxic effect of external Qi of Yan Xin Qigong (YXQ-EQ) on human
colorectal cancer cells. Methods: The effect of YXQ-EQ on viability, cell
cycle progression and apoptosis in colorectal cancer HT-29 cells was
investigated. Phosphorylation of Akt and Erk1/2, activation of NF-ĸB
and the expression of proteins involved in regulation of cell cycle and
apoptosis were examined by Western blot analysis. Results: YXQ-EQ markedly
decreased viability and blocked colony formation of HT-29 cells. YXQ-EQ
downregulated cyclin D1 expression and increased accumulation of cyclin-
dependent kinase inhibitors p21(Cip1) and p27(Kip1), resulting in G1 cell
cycle arrest. YXQ-EQ induced apoptosis in HT-29 cells in association with
decreased expression of antiapoptotic proteins Bcl-xL, XIAP, survivin and
Mcl-1 and elevated expression of proapoptotic protein Bax. YXQ-EQ
significantly repressed phosphorylation of Akt and Erk1/2 and NF-ĸB
activation in HT-29 cells, suggesting that YXQ-EQ may exert cytotoxic effect
through regulating signaling pathways critical for cell proliferation and
survival. Furthermore, YXQ-EQ treated PBS and an YXQ-EQ treated plant
extract induced apoptosis in HT-29 cells. Conclusion: These findings show
that YXQ-EQ has potent cytotoxic effect on HT-29 cells and suggest that YXQ-
EQ could be potentially used for colorectal cancer treatment either directly
or indirectly via carriers.
发信人: xiaomingxiao (xiaomingxiao), 信区: Biology
标 题: 气功大师发表的SCI，牛啊
发信站: BBS 未名空间站 (Mon Aug 5 15:48:20 2013, 美东)
Cell Physiol Biochem. 2013;31(1):113-22. doi: 10.1159/000343354. Epub 2013
Jan 25.
External Qi of Yan Xin Qigong inhibits activation of Akt, Erk1/2 and NF-
312;B and induces cell cycle arrest and apoptosis in colorectal cancer cells.
Yan X, Shen H, Jiang H, Hu D, Wang J, Wu X.
Background/Aims: Colorectal cancer (CRC) is the second leading cause of
cancer death in the Western countries. Novel approaches of treatment are
needed for CRC. The purpose of the present study was to investigate
cytotoxic effect of external Qi of Yan Xin Qigong (YXQ-EQ) on human
colorectal cancer cells. Methods: The effect of YXQ-EQ on viability, cell
cycle progression and apoptosis in colorectal cancer HT-29 cells was
investigated. Phosphorylation of Akt and Erk1/2, activation of NF-ĸB
and the expression of proteins involved in regulation of cell cycle and
apoptosis were examined by Western blot analysis. Results: YXQ-EQ markedly
decreased viability and blocked colony formation of HT-29 cells. YXQ-EQ
downregulated cyclin D1 expression and increased accumulation of cyclin-
dependent kinase inhibitors p21(Cip1) and p27(Kip1), resulting in G1 cell
cycle arrest. YXQ-EQ induced apoptosis in HT-29 cells in association with
decreased expression of antiapoptotic proteins Bcl-xL, XIAP, survivin and
Mcl-1 and elevated expression of proapoptotic protein Bax. YXQ-EQ
significantly repressed phosphorylation of Akt and Erk1/2 and NF-ĸB
activation in HT-29 cells, suggesting that YXQ-EQ may exert cytotoxic effect
through regulating signaling pathways critical for cell proliferation and
survival. Furthermore, YXQ-EQ treated PBS and an YXQ-EQ treated plant
extract induced apoptosis in HT-29 cells. Conclusion: These findings show
that YXQ-EQ has potent cytotoxic effect on HT-29 cells and suggest that YXQ-
EQ could be potentially used for colorectal cancer treatment either directly
or indirectly via carriers.
T*y
3 楼
等着换，好下单。。。。。
【在 T***y 的大作中提到】
: 我多余一个W开头的可以交换.
: 谢谢
【在 T***y 的大作中提到】
: 我多余一个W开头的可以交换.
: 谢谢
N*K
4 楼
no joke
这是严肃科学 不错 严新大师总算搞出点科学成果
cells.
【在 r******t 的大作中提到】
: 【 以下文字转载自 Biology 讨论区 】
: 发信人: xiaomingxiao (xiaomingxiao), 信区: Biology
: 标 题: 气功大师发表的SCI，牛啊
: 发信站: BBS 未名空间站 (Mon Aug 5 15:48:20 2013, 美东)
: Cell Physiol Biochem. 2013;31(1):113-22. doi: 10.1159/000343354. Epub 2013
: Jan 25.
: External Qi of Yan Xin Qigong inhibits activation of Akt, Erk1/2 and NF-
: 312;B and induces cell cycle arrest and apoptosis in colorectal cancer cells.
: Yan X, Shen H, Jiang H, Hu D, Wang J, Wu X.
: Background/Aims: Colorectal cancer (CRC) is the second leading cause of
这是严肃科学 不错 严新大师总算搞出点科学成果
cells.
【在 r******t 的大作中提到】
: 【 以下文字转载自 Biology 讨论区 】
: 发信人: xiaomingxiao (xiaomingxiao), 信区: Biology
: 标 题: 气功大师发表的SCI，牛啊
: 发信站: BBS 未名空间站 (Mon Aug 5 15:48:20 2013, 美东)
: Cell Physiol Biochem. 2013;31(1):113-22. doi: 10.1159/000343354. Epub 2013
: Jan 25.
: External Qi of Yan Xin Qigong inhibits activation of Akt, Erk1/2 and NF-
: 312;B and induces cell cycle arrest and apoptosis in colorectal cancer cells.
: Yan X, Shen H, Jiang H, Hu D, Wang J, Wu X.
: Background/Aims: Colorectal cancer (CRC) is the second leading cause of
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