c*i
2 楼
BBC Chinese, Jan 12, 2011.
http://www.bbc.co.uk/zhongwen
/simp/world/2011/01/110112_dna_test.shtml
My comment: The report is based on
Chiu RWK et al, Non-invasive prenatal assessment of trisomy 21 by
multiplexed maternal plasma DNA sequencing: large scale validity study.
British Medical Journal, 342: c7401 (2011).
http://www.bmj.com/content/342/bmj.c7401
(a) Quote from FULL TEXT (which is available free online by clicking the
button in the upper left corner of the web page):
"Cell-free DNA from the fetus has been found in the plasma of pregnant women
, and this has been used successfully for non-invasive determination of the
fetal sex and fetal RhD genotype in RhD negative women." Introduction.
"We extracted and sequenced DNA molecules from 2.0–4.8 mL of maternal
plasma using a protocol similar to that reported previously but with the
introduction of multiplexing.24 27 DNA molecules exist in maternal plasma as
short fragments. Methods.
(b) My comment:
(i) For RhD, see Rh blood group system
http://en.wikipedia.org/wiki/Rh_blood_group_system
(The Rh blood group system (including the Rh factor) is one of the currently
30 human blood group systems. It is clinically the most important blood
group system after ABO. The Rh blood group system currently consists of 50
defined blood-group antigens, among which the 5 antigens D, C, c, E, and e
are the most important ones. The commonly-used terms Rh factor, Rh positive
and Rh negative refer to the D antigen only.)
(ii) I do not know the meaning of multiplexing, which is under the heading "
Maternal plasma DNA sequencing" in Methods of full text.
(iii) sensitivity and specificity
http://en.wikipedia.org/wiki/Sensitivity_and_specificity
(Sensitivity measures the proportion of actual positives which are correctly
identified as such (e.g. the percentage of sick people who are correctly
identified as having the condition). Specificity measures the proportion of
negatives which are correctly identified (e.g. the percentage of healthy
people who are correctly identified as not having the condition).)
http://www.bbc.co.uk/zhongwen
/simp/world/2011/01/110112_dna_test.shtml
My comment: The report is based on
Chiu RWK et al, Non-invasive prenatal assessment of trisomy 21 by
multiplexed maternal plasma DNA sequencing: large scale validity study.
British Medical Journal, 342: c7401 (2011).
http://www.bmj.com/content/342/bmj.c7401
(a) Quote from FULL TEXT (which is available free online by clicking the
button in the upper left corner of the web page):
"Cell-free DNA from the fetus has been found in the plasma of pregnant women
, and this has been used successfully for non-invasive determination of the
fetal sex and fetal RhD genotype in RhD negative women." Introduction.
"We extracted and sequenced DNA molecules from 2.0–4.8 mL of maternal
plasma using a protocol similar to that reported previously but with the
introduction of multiplexing.24 27 DNA molecules exist in maternal plasma as
short fragments. Methods.
(b) My comment:
(i) For RhD, see Rh blood group system
http://en.wikipedia.org/wiki/Rh_blood_group_system
(The Rh blood group system (including the Rh factor) is one of the currently
30 human blood group systems. It is clinically the most important blood
group system after ABO. The Rh blood group system currently consists of 50
defined blood-group antigens, among which the 5 antigens D, C, c, E, and e
are the most important ones. The commonly-used terms Rh factor, Rh positive
and Rh negative refer to the D antigen only.)
(ii) I do not know the meaning of multiplexing, which is under the heading "
Maternal plasma DNA sequencing" in Methods of full text.
(iii) sensitivity and specificity
http://en.wikipedia.org/wiki/Sensitivity_and_specificity
(Sensitivity measures the proportion of actual positives which are correctly
identified as such (e.g. the percentage of sick people who are correctly
identified as having the condition). Specificity measures the proportion of
negatives which are correctly identified (e.g. the percentage of healthy
people who are correctly identified as not having the condition).)
m*a
3 楼
我去年没有缴税，所以W2上的收入为0，我用H&R软件报税，软件上只提到输入W2表的内容，没有地方要输入1042S表的信息。请问一定要输入吗？在哪里输入1042S内容？
l*d
4 楼
二百零四瓣，一朝熄火英雄均扼腕。
盛筵总有散，屌丝无须为此心留恋。
盛筵总有散，屌丝无须为此心留恋。
m*y
5 楼
考古了一下，好象以前大家常用的washington mutual fund 和Wachovia都被收购了，
现在大家都用啥？
现在大家都用啥？
m*a
6 楼
看来还是挺复杂的问题。
c*r
7 楼
哈哈 赞屌丝无须为此心留恋
【在 l*****d 的大作中提到】
: 二百零四瓣，一朝熄火英雄均扼腕。
: 盛筵总有散，屌丝无须为此心留恋。
【在 l*****d 的大作中提到】
: 二百零四瓣，一朝熄火英雄均扼腕。
: 盛筵总有散，屌丝无须为此心留恋。
h*e
8 楼
去银行wire transfer，无论汇多少一个价，20-30刀，24小时就到了,安全方便，一直
用这个
【在 m******y 的大作中提到】
: 从来没有汇过，不知道怎么弄
用这个
【在 m******y 的大作中提到】
: 从来没有汇过，不知道怎么弄
m*7
9 楼
没地方输入就把表格寄过去
内容，没有地方要输入1042S表的信息。请问一定要输入吗？在哪里输入1042S内容？
【在 m*****a 的大作中提到】
: 我去年没有缴税，所以W2上的收入为0，我用H&R软件报税，软件上只提到输入W2表的内容，没有地方要输入1042S表的信息。请问一定要输入吗？在哪里输入1042S内容？
内容，没有地方要输入1042S表的信息。请问一定要输入吗？在哪里输入1042S内容？
【在 m*****a 的大作中提到】
: 我去年没有缴税，所以W2上的收入为0，我用H&R软件报税，软件上只提到输入W2表的内容，没有地方要输入1042S表的信息。请问一定要输入吗？在哪里输入1042S内容？
m*y
10 楼
boa 收２５国内，４５国际, 那个银行收２０－３０呀？
t*0
11 楼
If you file 1042, put the amount in 1042s in line 21, like this ($$$$$). But
you may have to file using the paper form, not efile.
you may have to file using the paper form, not efile.
s*n
12 楼
Ally (Former Gmac)收$20，无上限，国际国内一样
【在 m******y 的大作中提到】
: boa 收２５国内，４５国际, 那个银行收２０－３０呀？
【在 m******y 的大作中提到】
: boa 收２５国内，４５国际, 那个银行收２０－３０呀？
m*a
13 楼
如果我把1042s上的工资放在21，软件会算出我差2700多的州税。
But
【在 t*******0 的大作中提到】
: If you file 1042, put the amount in 1042s in line 21, like this ($$$$$). But
: you may have to file using the paper form, not efile.
But
【在 t*******0 的大作中提到】
: If you file 1042, put the amount in 1042s in line 21, like this ($$$$$). But
: you may have to file using the paper form, not efile.
k*u
14 楼
就是 这个 25 可以汇到中国，去Money精华区看看。
boa 收２５国内，４５国际, 那个银行收２０－３０呀？
【在 m******y 的大作中提到】
: boa 收２５国内，４５国际, 那个银行收２０－３０呀？
boa 收２５国内，４５国际, 那个银行收２０－３０呀？
【在 m******y 的大作中提到】
: boa 收２５国内，４５国际, 那个银行收２０－３０呀？
w*g
15 楼
don't put it anywhere.
【在 m*****a 的大作中提到】
: 如果我把1042s上的工资放在21，软件会算出我差2700多的州税。
:
: But
【在 m*****a 的大作中提到】
: 如果我把1042s上的工资放在21，软件会算出我差2700多的州税。
:
: But
k*x
16 楼
If you have wamu checking account before chase took it over, you can wire to
China for free.
【在 m******y 的大作中提到】
: 考古了一下，好象以前大家常用的washington mutual fund 和Wachovia都被收购了，
: 现在大家都用啥？
China for free.
【在 m******y 的大作中提到】
: 考古了一下，好象以前大家常用的washington mutual fund 和Wachovia都被收购了，
: 现在大家都用啥？
m*a
17 楼
正解！！！！！！！！
【在 w*******g 的大作中提到】
: don't put it anywhere.
【在 w*******g 的大作中提到】
: don't put it anywhere.
c*n
18 楼
use the bank of China new york online; $12, money transferred to bank of
china in 3 days.
china in 3 days.
J*o
19 楼
具体说说？
【在 c*****n 的大作中提到】
: use the bank of China new york online; $12, money transferred to bank of
: china in 3 days.
【在 c*****n 的大作中提到】
: use the bank of China new york online; $12, money transferred to bank of
: china in 3 days.
c*n
20 楼
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