b*y
2 楼
those cytosolic proteins are translated in the cytosol and not through ER.
only membrane-tethered and secreted proteins are through ER.
only membrane-tethered and secreted proteins are through ER.
b*y
4 楼
Some proteins do need chaperone for folding and stability and there are
plenty in cytosol, for example, heat shock proteins. Protein surface
disulfide bonds are rare in cytosolic proteins although there are some in
interior of the proteins. 糖基化 is not that common for cytosolic proteins,
either.
plenty in cytosol, for example, heat shock proteins. Protein surface
disulfide bonds are rare in cytosolic proteins although there are some in
interior of the proteins. 糖基化 is not that common for cytosolic proteins,
either.
Q*n
5 楼
那么mRNA是怎么知道要去细胞质或ER的呢?
l*1
9 楼
RE: 这些游来游去的蛋白是在细胞质里翻译的,还是在翻译的过程中先进入ER,然后转移出
来的?
CERT protein is localized on perinuclear regions
References:
a, JBC (2006)
htp://www.ncbi.nlm.nih.gov/pubmed/16895911
b, BBA (2007)
htp://www.ncbi.nlm.nih.gov/pubmed/17314061
c, Adv Exp Med Biol. 2010;688:1-23.
htp://www.ncbi.nlm.nih.gov/pubmed/20919643
【在 V***b 的大作中提到】
: 这些游来游去的蛋白是在细胞质里翻译的,还是在翻译的过程中先进入ER,然后转移出
: 来的?困扰我很久了。
来的?
CERT protein is localized on perinuclear regions
References:
a, JBC (2006)
htp://www.ncbi.nlm.nih.gov/pubmed/16895911
b, BBA (2007)
htp://www.ncbi.nlm.nih.gov/pubmed/17314061
c, Adv Exp Med Biol. 2010;688:1-23.
htp://www.ncbi.nlm.nih.gov/pubmed/20919643
【在 V***b 的大作中提到】
: 这些游来游去的蛋白是在细胞质里翻译的,还是在翻译的过程中先进入ER,然后转移出
: 来的?困扰我很久了。
l*1
10 楼
RE
来篇中文的论文/译文?
Abstracts in english:
Molecular Mechanism of CERT in Non2vesicular Transfer
by XU Jia Li , GUO Jun
Chinese Journal of Biochemistry and Molecular Biology (2009)
full text link:
htp://cjbmb.bjmu.edu.cn/CN/article/downloadArticleFile.do?attachType=PDF&id=
19135
不过可以说是楼上 JBC 2006 paper 的中文译文啊?
【在 Q*****n 的大作中提到】
: 就是说先翻译出一点来再转到ER上?
来篇中文的论文/译文?
Abstracts in english:
Molecular Mechanism of CERT in Non2vesicular Transfer
by XU Jia Li , GUO Jun
Chinese Journal of Biochemistry and Molecular Biology (2009)
full text link:
htp://cjbmb.bjmu.edu.cn/CN/article/downloadArticleFile.do?attachType=PDF&id=
19135
不过可以说是楼上 JBC 2006 paper 的中文译文啊?
【在 Q*****n 的大作中提到】
: 就是说先翻译出一点来再转到ER上?
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