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比较基因组学问题请教
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比较基因组学问题请教# Biology - 生物学
v*n
1
Sorry to see the post about interview experience in
Google has been deleted by the OP. The whole purpose
of my post won't be upon whether we should obey the
NDA or whether we should share the interview questions.
As the title, man be man, so his code should be honored
anyways. I do appericiate those who post their
interview experience ignoring the NDA yet I also feel
grateful for people who contribute by posting their own
experience without concrete context.
However, I do feel bad about certain people who are
desperately seeking for the questions in order to
prepare for their interviews at Google/Amazon/Microsoft/You
name it. What makes a good candidate, IMHO, is not how many
questions he memorized before coming down for the interview,
but more would be based upon his professionalism, intelligence,
and/or even his personality.
The feeling gets even worse when I saw experienced people
on this board still value more about the concrete questions
instead of anything else. Again just IMHO, unless you are
fresh, just out of college, these questions won't help you
a lot given that they are designed to raise the bar and test
the entry level programmers. What makes veteran employee more
valuable is the experience that could lead to their visions
of the industry and their own careers. Thus, a more important
question should be "where would you see yourself in 2 years,
5 years, or 10 years?". Being a coding guru (a.k.a. coding
monkey) does not hurt but isn't there something else could
be pursued?
Just typing down my random thoughts during lunch and please
help correct me.
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o*n
2
大家好,
我有几十个细菌isolates,从不同的宿主和环境下培养出来,测了它们的基因组。我想
通过比较它们的基因组来分析它们怎么适应不同的宿主或环境的。
现在我拿到的data是Illumina测序后的全基因组DNA fastq file,我们的合作者应该也
给它们做了annotation,以后才会拿到。
我不会写perl/python,会一点R。请问对于新手,有什么好的程序或package,让我可
以做些初步分析?另外,是不是只有做过annotation的序列才适合分析,纯DNA序列没
法怎么分析?
谢谢任何建议或帮助。
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y*r
3
我觉得前面那个贴google面试过程的帖子的朋友挺委屈的,人家贴也是想给大家提供些
信息,对读的人有多大用因人而已,非要上升到什么高度甚至人生攻击实在太过了。
都想这样那些没能把所有的面试题公布出来的是不是就不要来贴呢?每个人都有自己的
做事标准,大家还是应该professional一点,应该学会感谢别人的劳动。
至少我想学习的不是什么具体的题目,而是某个公司的风格,公司想找的是什么类型的
人。所以看看科普的帖子也觉得有用。

【在 v***n 的大作中提到】
: Sorry to see the post about interview experience in
: Google has been deleted by the OP. The whole purpose
: of my post won't be upon whether we should obey the
: NDA or whether we should share the interview questions.
: As the title, man be man, so his code should be honored
: anyways. I do appericiate those who post their
: interview experience ignoring the NDA yet I also feel
: grateful for people who contribute by posting their own
: experience without concrete context.
: However, I do feel bad about certain people who are

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t*w
4
you will be fine to continue R progrmaming
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v*n
5

对的
我也是觉得很可惜...

【在 y**r 的大作中提到】
: 我觉得前面那个贴google面试过程的帖子的朋友挺委屈的,人家贴也是想给大家提供些
: 信息,对读的人有多大用因人而已,非要上升到什么高度甚至人生攻击实在太过了。
: 都想这样那些没能把所有的面试题公布出来的是不是就不要来贴呢?每个人都有自己的
: 做事标准,大家还是应该professional一点,应该学会感谢别人的劳动。
: 至少我想学习的不是什么具体的题目,而是某个公司的风格,公司想找的是什么类型的
: 人。所以看看科普的帖子也觉得有用。

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o*n
6
我查到的r packages多是用来作图的,好像没找到能同时比较很多基因组的呢,你能具
体说下吗?:)

【在 t*****w 的大作中提到】
: you will be fine to continue R progrmaming
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