m*g
2 楼
我的已经4个多月了,一点动静没有。考虑要不要改PREMIUM。。。。
除了网上查状态之外,有没有别的联系USCIS的办法啊?
除了网上查状态之外,有没有别的联系USCIS的办法啊?
j*3
3 楼
楚乔传中燕询在黑化之后疯狂的复仇,这是一点毛病没有的。隔谁都会复仇的,怎么说
呢,一家无缘无故被魏皇灭了,如果真是谋反就算了,也是死有余辜。但是这根本就是
子虚乌有的事情,因此燕询报仇也是理所应当的。
问题在于报仇归报仇,能不能不要不择手段。即使是不择手段的报仇成功之后,燕询同
样没有放下屠刀立地成佛,而是变成了另外一个魏帝。可能皇帝都是这样的样子吧,但
是泯灭心智之后的燕询下场可能和魏帝没什么两样。
不能说燕询黑化就是一种简单的变化,而是说燕询骨子中还是有这些基因。因为一个傻
瓜是不会突然见变得很聪明的。就像刘禅一样,哪怕天天做皇帝也没有见他会雄才大略
。即便是最后被魏国灭了,魏国也放心的留在外地做王,也没杀死他,因为知道他除了
吃喝玩乐什么都不会干。
呢,一家无缘无故被魏皇灭了,如果真是谋反就算了,也是死有余辜。但是这根本就是
子虚乌有的事情,因此燕询报仇也是理所应当的。
问题在于报仇归报仇,能不能不要不择手段。即使是不择手段的报仇成功之后,燕询同
样没有放下屠刀立地成佛,而是变成了另外一个魏帝。可能皇帝都是这样的样子吧,但
是泯灭心智之后的燕询下场可能和魏帝没什么两样。
不能说燕询黑化就是一种简单的变化,而是说燕询骨子中还是有这些基因。因为一个傻
瓜是不会突然见变得很聪明的。就像刘禅一样,哪怕天天做皇帝也没有见他会雄才大略
。即便是最后被魏国灭了,魏国也放心的留在外地做王,也没杀死他,因为知道他除了
吃喝玩乐什么都不会干。
s*y
4 楼
美国高等法院今日裁定,在自然界自然存在的人类基因不能作为专利。
http://news.yahoo.com/court-says-human-genes-cannot-patented-14
Court says human genes cannot be patented
Associated PressBy JESSE J. HOLLAND | Associated Press – 5 mins ago
WASHINGTON (AP) — The Supreme Court ruled Thursday that companies cannot
patent parts of naturally-occurring human genes, a decision with the
potential to profoundly affect the emerging and lucrative medical and
biotechnology industries.
The high court's unanimous judgment reverses three decades of patent awards
by government officials. It throws out patents held by Salt Lake City-based
Myriad Genetics Inc. on an increasingly popular breast cancer test brought
into the public eye recently by actress Angelina Jolie's revelation that she
had a double mastectomy because of one of the genes involved in this case.
Justice Clarence Thomas, who wrote the court's decision, said that Myriad's
assertion — that the DNA it isolated from the body for its proprietary
breast and ovarian cancer tests were patentable — had to be dismissed
because it violates patent rules. The court has said that laws of nature,
natural phenomena and abstract ideas are not patentable.
"We hold that a naturally occurring DNA segment is a product of nature and
not patent eligible merely because it has been isolated," Thomas said.
Patents are the legal protection that gives inventors the right to prevent
others from making, using or selling a novel device, process or application.
The U.S. Patent and Trademark Office has been awarding patents on human
genes for almost 30 years, but opponents of Myriad Genetics Inc.'s patents
on the two genes linked to increased risk of breast and ovarian cancer say
such protection should not be given to something that can be found inside
the human body.
The company has used its patent to come up with its BRACAnalysis test, which
looks for mutations on the breast cancer predisposition gene, or BRCA.
Those mutations are associated with much greater risks of breast and ovarian
cancer. Women with a faulty gene have a three to seven times greater risk
of developing breast cancer and also have a higher risk of ovarian cancer.
Myriad sells the only BRCA gene test. Opponents of its patents say the
company can use the patents to keep other researchers from working with the
BRCA gene to develop other tests.
"Today, the court struck down a major barrier to patient care and medical
innovation," said Sandra Park, a lawyer for the American Civil Liberties
Union Women's Rights Project. "Myriad did not invent the BRCA genes and
should not control them. Because of this ruling, patients will have greater
access to genetic testing and scientists can engage in research on these
genes without fear of being sued."
Jolie revealed last month that her mother died of ovarian cancer and that
her maternal grandmother also had the disease. She said she carries a
defective BRCA1 gene that puts her at high risk of developing breast and
ovarian cancers, and her doctor said that the test that turned up the faulty
gene link led Jolie to have both of her healthy breasts removed to try to
avoid the same fate.
Companies have billions of dollars of investment and years of research on
the line in this case. Their advocates argue that without the ability to
recoup their investment through the profits that patents bring, breakthrough
scientific discoveries to combat all kinds of medical maladies wouldn't
happen.
But "genes and the information they encode area not patent eligible ...
simply because they have been isolated from the surrounding genetic material
," Thomas said.
In a concurring opinion, Justice Antonin Scalia said "the portion of the DNA
isolated from its natural state sought to be patented is identical to that
portion of the DNA in its natural state."
A Myriad spokesman did not immediately respond to a request for comment.
The court did rule that synthetically created DNA, known as cDNA, can be
patented "because it is not naturally occurring," Thomas said.
And Thomas noted there are still ways for Myriad to make money off its
discovery. "Had Myriad created an innovative method of manipulating genes
while searching for the BRCA1 and BRCA2 genes, it could possibly have sought
a method patent," he said. And he noted that the case before the court did
not include patents on the application of knowledge about the two genes.
The case is 12-398, Association for Molecular Pathology v. Myriad Genetics,
Inc.
http://news.yahoo.com/court-says-human-genes-cannot-patented-14
Court says human genes cannot be patented
Associated PressBy JESSE J. HOLLAND | Associated Press – 5 mins ago
WASHINGTON (AP) — The Supreme Court ruled Thursday that companies cannot
patent parts of naturally-occurring human genes, a decision with the
potential to profoundly affect the emerging and lucrative medical and
biotechnology industries.
The high court's unanimous judgment reverses three decades of patent awards
by government officials. It throws out patents held by Salt Lake City-based
Myriad Genetics Inc. on an increasingly popular breast cancer test brought
into the public eye recently by actress Angelina Jolie's revelation that she
had a double mastectomy because of one of the genes involved in this case.
Justice Clarence Thomas, who wrote the court's decision, said that Myriad's
assertion — that the DNA it isolated from the body for its proprietary
breast and ovarian cancer tests were patentable — had to be dismissed
because it violates patent rules. The court has said that laws of nature,
natural phenomena and abstract ideas are not patentable.
"We hold that a naturally occurring DNA segment is a product of nature and
not patent eligible merely because it has been isolated," Thomas said.
Patents are the legal protection that gives inventors the right to prevent
others from making, using or selling a novel device, process or application.
The U.S. Patent and Trademark Office has been awarding patents on human
genes for almost 30 years, but opponents of Myriad Genetics Inc.'s patents
on the two genes linked to increased risk of breast and ovarian cancer say
such protection should not be given to something that can be found inside
the human body.
The company has used its patent to come up with its BRACAnalysis test, which
looks for mutations on the breast cancer predisposition gene, or BRCA.
Those mutations are associated with much greater risks of breast and ovarian
cancer. Women with a faulty gene have a three to seven times greater risk
of developing breast cancer and also have a higher risk of ovarian cancer.
Myriad sells the only BRCA gene test. Opponents of its patents say the
company can use the patents to keep other researchers from working with the
BRCA gene to develop other tests.
"Today, the court struck down a major barrier to patient care and medical
innovation," said Sandra Park, a lawyer for the American Civil Liberties
Union Women's Rights Project. "Myriad did not invent the BRCA genes and
should not control them. Because of this ruling, patients will have greater
access to genetic testing and scientists can engage in research on these
genes without fear of being sued."
Jolie revealed last month that her mother died of ovarian cancer and that
her maternal grandmother also had the disease. She said she carries a
defective BRCA1 gene that puts her at high risk of developing breast and
ovarian cancers, and her doctor said that the test that turned up the faulty
gene link led Jolie to have both of her healthy breasts removed to try to
avoid the same fate.
Companies have billions of dollars of investment and years of research on
the line in this case. Their advocates argue that without the ability to
recoup their investment through the profits that patents bring, breakthrough
scientific discoveries to combat all kinds of medical maladies wouldn't
happen.
But "genes and the information they encode area not patent eligible ...
simply because they have been isolated from the surrounding genetic material
," Thomas said.
In a concurring opinion, Justice Antonin Scalia said "the portion of the DNA
isolated from its natural state sought to be patented is identical to that
portion of the DNA in its natural state."
A Myriad spokesman did not immediately respond to a request for comment.
The court did rule that synthetically created DNA, known as cDNA, can be
patented "because it is not naturally occurring," Thomas said.
And Thomas noted there are still ways for Myriad to make money off its
discovery. "Had Myriad created an innovative method of manipulating genes
while searching for the BRCA1 and BRCA2 genes, it could possibly have sought
a method patent," he said. And he noted that the case before the court did
not include patents on the application of knowledge about the two genes.
The case is 12-398, Association for Molecular Pathology v. Myriad Genetics,
Inc.
y*i
5 楼
这个挺幽默的,我炒黑芝麻的时候会放点儿白的做indicator
s*y
6 楼
拥有BRAC1专利的公司要哭了
awards
【在 s******y 的大作中提到】
: 美国高等法院今日裁定,在自然界自然存在的人类基因不能作为专利。
: http://news.yahoo.com/court-says-human-genes-cannot-patented-14
: Court says human genes cannot be patented
: Associated PressBy JESSE J. HOLLAND | Associated Press – 5 mins ago
:
: WASHINGTON (AP) — The Supreme Court ruled Thursday that companies cannot
: patent parts of naturally-occurring human genes, a decision with the
: potential to profoundly affect the emerging and lucrative medical and
: biotechnology industries.
: The high court's unanimous judgment reverses three decades of patent awards
awards
【在 s******y 的大作中提到】
: 美国高等法院今日裁定,在自然界自然存在的人类基因不能作为专利。
: http://news.yahoo.com/court-says-human-genes-cannot-patented-14
: Court says human genes cannot be patented
: Associated PressBy JESSE J. HOLLAND | Associated Press – 5 mins ago
:
: WASHINGTON (AP) — The Supreme Court ruled Thursday that companies cannot
: patent parts of naturally-occurring human genes, a decision with the
: potential to profoundly affect the emerging and lucrative medical and
: biotechnology industries.
: The high court's unanimous judgment reverses three decades of patent awards
j*x
12 楼
这个判例太关键啦。。。
awards
based
【在 s******y 的大作中提到】
: 美国高等法院今日裁定,在自然界自然存在的人类基因不能作为专利。
: http://news.yahoo.com/court-says-human-genes-cannot-patented-14
: Court says human genes cannot be patented
: Associated PressBy JESSE J. HOLLAND | Associated Press – 5 mins ago
:
: WASHINGTON (AP) — The Supreme Court ruled Thursday that companies cannot
: patent parts of naturally-occurring human genes, a decision with the
: potential to profoundly affect the emerging and lucrative medical and
: biotechnology industries.
: The high court's unanimous judgment reverses three decades of patent awards
awards
based
【在 s******y 的大作中提到】
: 美国高等法院今日裁定,在自然界自然存在的人类基因不能作为专利。
: http://news.yahoo.com/court-says-human-genes-cannot-patented-14
: Court says human genes cannot be patented
: Associated PressBy JESSE J. HOLLAND | Associated Press – 5 mins ago
:
: WASHINGTON (AP) — The Supreme Court ruled Thursday that companies cannot
: patent parts of naturally-occurring human genes, a decision with the
: potential to profoundly affect the emerging and lucrative medical and
: biotechnology industries.
: The high court's unanimous judgment reverses three decades of patent awards
H*e
13 楼
This is good news to all! It means that all applications around any gene
are open to everyone "equally". However, big guys have more chances. Small
people like can still acquire some if we can make a little breakthrough!
are open to everyone "equally". However, big guys have more chances. Small
people like can still acquire some if we can make a little breakthrough!
f*u
14 楼
我不是太理解你说的。
据个例子,如果一个研究组发现了某个基因的突变跟某种疾病有关联,
这个组的人想开个公司专门诊断这个基因有没有突变,然后给病人进行评估。
那这里的知识产权怎么保护?按照这个法案不是人人都可以开发检测试剂了?
大家都知道想要诊断一个基因有没有突变现在太容易了,关键是要知道检验那个基因。
我只是想知道这个判例以下来,会不会对打击寻找致病基因的积极性,
因为大家都愿意等现成的,等人家把基因找到了我随便弄个检测试剂什么的。
Small
【在 H*****e 的大作中提到】
: This is good news to all! It means that all applications around any gene
: are open to everyone "equally". However, big guys have more chances. Small
: people like can still acquire some if we can make a little breakthrough!
据个例子,如果一个研究组发现了某个基因的突变跟某种疾病有关联,
这个组的人想开个公司专门诊断这个基因有没有突变,然后给病人进行评估。
那这里的知识产权怎么保护?按照这个法案不是人人都可以开发检测试剂了?
大家都知道想要诊断一个基因有没有突变现在太容易了,关键是要知道检验那个基因。
我只是想知道这个判例以下来,会不会对打击寻找致病基因的积极性,
因为大家都愿意等现成的,等人家把基因找到了我随便弄个检测试剂什么的。
Small
【在 H*****e 的大作中提到】
: This is good news to all! It means that all applications around any gene
: are open to everyone "equally". However, big guys have more chances. Small
: people like can still acquire some if we can make a little breakthrough!
F*p
16 楼
绝大多数的疾病基因突变都是用纳税人的钱在公立研究机构发现的
H*e
19 楼
You can also say:
随便弄个疾病有关联什么的, a gene can be patent and prevent others from
further exploration.
【在 f**u 的大作中提到】
: 我不是太理解你说的。
: 据个例子,如果一个研究组发现了某个基因的突变跟某种疾病有关联,
: 这个组的人想开个公司专门诊断这个基因有没有突变,然后给病人进行评估。
: 那这里的知识产权怎么保护?按照这个法案不是人人都可以开发检测试剂了?
: 大家都知道想要诊断一个基因有没有突变现在太容易了,关键是要知道检验那个基因。
: 我只是想知道这个判例以下来,会不会对打击寻找致病基因的积极性,
: 因为大家都愿意等现成的,等人家把基因找到了我随便弄个检测试剂什么的。
:
: Small
随便弄个疾病有关联什么的, a gene can be patent and prevent others from
further exploration.
【在 f**u 的大作中提到】
: 我不是太理解你说的。
: 据个例子,如果一个研究组发现了某个基因的突变跟某种疾病有关联,
: 这个组的人想开个公司专门诊断这个基因有没有突变,然后给病人进行评估。
: 那这里的知识产权怎么保护?按照这个法案不是人人都可以开发检测试剂了?
: 大家都知道想要诊断一个基因有没有突变现在太容易了,关键是要知道检验那个基因。
: 我只是想知道这个判例以下来,会不会对打击寻找致病基因的积极性,
: 因为大家都愿意等现成的,等人家把基因找到了我随便弄个检测试剂什么的。
:
: Small
b*k
21 楼
现在已经跌回来了
http://www.nasdaq.com/symbol/mygn
【在 b****r 的大作中提到】
: 怀疑是有人搞鬼,很多人都买跌,结果反而涨,那些人血本无归
: 再怎么上下游专利保护,对Myriad肯定不会是利好,这些年Myriad那可是真是赚得太爽
: 了,整个BRCA1,2的领域都被他吃得死死的,连科研都很难开展
http://www.nasdaq.com/symbol/mygn
【在 b****r 的大作中提到】
: 怀疑是有人搞鬼,很多人都买跌,结果反而涨,那些人血本无归
: 再怎么上下游专利保护,对Myriad肯定不会是利好,这些年Myriad那可是真是赚得太爽
: 了,整个BRCA1,2的领域都被他吃得死死的,连科研都很难开展
f*u
24 楼
也不能这么说吧,抗生素什么的也都是天然的,你如果能筛到一个新的肯定能专利。
另外我也听有人说现在发现个疾病基因什么的很容易,所以可以算obvious的。
这也有问题,发现疾病相关的突变可能需要侧记是个tumor sample,
或者用几千个人作GWAS,后面还需要valid,我不觉得这个能算明显。
【在 b******k 的大作中提到】
: 这个本身没有太不合理 因为mutation是天然存在的 不是谁创造出来的 天然存在的东
: 西怎么能算patent呢
: 我觉得这个裁决的大背景是 现在鉴定一个疾病的genetics没有那么困难了 因此司法系
: 统没有incentive要通过patent来鼓励私人资本的投入
另外我也听有人说现在发现个疾病基因什么的很容易,所以可以算obvious的。
这也有问题,发现疾病相关的突变可能需要侧记是个tumor sample,
或者用几千个人作GWAS,后面还需要valid,我不觉得这个能算明显。
【在 b******k 的大作中提到】
: 这个本身没有太不合理 因为mutation是天然存在的 不是谁创造出来的 天然存在的东
: 西怎么能算patent呢
: 我觉得这个裁决的大背景是 现在鉴定一个疾病的genetics没有那么困难了 因此司法系
: 统没有incentive要通过patent来鼓励私人资本的投入
v*e
28 楼
没好处,以后生物界钱更少了。失业的人更多了。
S*l
32 楼
是的. 可是 致病基因的发现却没有停止. 现在的HGMD, OMIM数据库比一两年多了很多
新致病基因. Myriad也挣饱了. 该知足了. 没他们,BRAC1/2一样会被别人找到. 而且他
们的成果建立在多少年别人的被NIH资助的研究成果上,尤其是Mary-Clarie King的.
http://www.slate.com/articles/health_and_science/new_scientist/
http://www.pbs.org/wgbh/nova/next/body/gene-patents-and-persona
【在 b****r 的大作中提到】
: 据我所知,已经多年没有什么新的人类致病基因被批准专利了。Myriad完全是一枝独秀
: /众矢之的
新致病基因. Myriad也挣饱了. 该知足了. 没他们,BRAC1/2一样会被别人找到. 而且他
们的成果建立在多少年别人的被NIH资助的研究成果上,尤其是Mary-Clarie King的.
http://www.slate.com/articles/health_and_science/new_scientist/
http://www.pbs.org/wgbh/nova/next/body/gene-patents-and-persona
【在 b****r 的大作中提到】
: 据我所知,已经多年没有什么新的人类致病基因被批准专利了。Myriad完全是一枝独秀
: /众矢之的
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