Doug Melton分化出来人beta细胞了 - 未名空间MITBBS历史存档

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Doug Melton分化出来人beta细胞了

Doug Melton分化出来人beta细胞了# Biology - 生物学

D*a2014-10-09 07:10

1 楼

http://www.sciencedirect.com/science/article/pii/S0092867414012
Here, we report a scalable differentiation protocol that can generate
hundreds of millions of glucose-responsive β cells from hPSC in vitro.
These stem-cell-derived β cells (SC-β) express markers found in mature β
cells, flux Ca2+ in response to glucose, package insulin into secretory
granules, and secrete quantities of insulin comparable to adult β cells in
response to multiple sequential glucose challenges in vitro.

B*o2014-10-09 07:10

2 楼

他挖的坑挺多的，是不是真的还得别家confirm才行。

β
in

【在 D*a 的大作中提到】

: http://www.sciencedirect.com/science/article/pii/S0092867414012
: Here, we report a scalable differentiation protocol that can generate
: hundreds of millions of glucose-responsive β cells from hPSC in vitro.
: These stem-cell-derived β cells (SC-β) express markers found in mature β
: cells, flux Ca2+ in response to glucose, package insulin into secretory
: granules, and secrete quantities of insulin comparable to adult β cells in
: response to multiple sequential glucose challenges in vitro.