Company = Portola Pharmaceuticals City = South San Francisco, CA 94080 Telephone = (650) 246-7387 email = c*****[email protected] --------------------- Position Title = Scientist II, Medicinal Chemistry Job Description = Have responsibility for the optimization of chemical leads through the utilization of SAR, structure-based design for potency, selectivity and pharmacokinetic profile Support the development of clinical candidates through designing synthetic routes, synthesizing impurities, major metabolites and degradants Education = PhD in organic, medicinal or pharmaceutical chemistry with a minimum of 3-5 years of relevant industry work experience Experience = Strong command of synthetic organic chemistry laboratory skills , Demonstrated excellence in applying medicinal chemistry to address selectivity, PK/ADME and toxicology issues Strong analytical skills employing characterization and purification techniques, i.e. normal phase chromatography and reverse phase HPLC Job Location = South San Francisco, CA Salary = DOE Employer Description = Portola Pharmaceuticals completed an IPO in May 2013 and has nearly 75 employees. Our goal is to build a biopharmaceutical company with compounds that advance the care of patients in the areas of thrombosis and other hematologic disorders and inflammation. Application Instructions = Please submit a cover letter that highlights your qualifications and matches our requirements along with your resume to c*****[email protected]