rheumotoid arthritis 很多都有严重的inflammation问题,很多inflammation的疾病
都很难以处理,现在似乎主要的治疗办法就是各种anti-inflammatory drugs,处理炎症
疼痛。
虽然很多的植物成分发现了有anti-inflammatory的作用,比如说有文献支持omega-3
fatty acids有作用,或者可以降低需要的anti-inflammatory drugs。但是,这些证据
都是很不充分的。鱼油的研究算是比较多的。
Three meta-analyses of randomized controlled trials in rheumatoid arthritis
patients found that fish oil supplementation significantly decreased the
number of painful and/or tender joints on physical examination。 The papers
are below:
Fortin, P. R., Lew, R. A., Liang, M. H., Wright, E. A., Beckett, L. A.,
Chalmers, T. C., and Sperling, R. I. (1995) Validation of a meta-analysis:
the effects of fish oil in rheumatoid arthritis. J Clin Epidemiol 48, 1379-
1390
MacLean CH, Mojica WA, Morton SC, et al. Effects of omega-3 fatty acids on
lipids and glycemic control in type II diabetes and the metabolic syndrome
and on inflammatory bowel disease, rheumatoid arthritis, renal disease,
systemic lupus erythematosus, and osteoporosis. Evid Rep Technol Assess (
Summ). 2004(89):1-4.
Goldberg RJ, Katz J. A meta-analysis of the analgesic effects of omega-3
polyunsaturated fatty acid supplementation for inflammatory joint pain. Pain
. 2007;129(1-2):210-223.