The United States Court of Appeals for the Federal Circuit has the exclusive
jurisdiction on patent cases on appeal. That is, its decision is binding to
all lower federal courts. So far, In re Bilski is a good law, which is
unlikely to be overruled by the Supreme Court in a foreseeable future (in
view of its recent decision in Mayo v. Prometheus).
So it is unlikely that a pure business trading method would be a patentable
subject matter.