大家在孕晚期都打TDAP疫苗吗？# NextGeneration - 我爱宝宝
s*e
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OB建议在过了孕28周打，还说现在美国这个是新生儿高发病之一。可是我看了宝宝版的
精华贴，是这样说的：
DTaP在孕妇中没有很多安全和有效性数据，所以如果选择请慎重考虑。CDC是这样建议
的：
Pregnancy is not a contraindication for use of Tdap. Data on safety,
immunogenicity and the outcomes of pregnancy are not available for pregnant
women who receive Tdap.When Tdap is administered during pregnancy,
transplacental maternal antibodies might protect the infant against
pertussis in early life. They also could interfere with the infant's immune
response to infant doses of DTaP, and leave the infant less well protected
against pertussis.
ACIP recommends Td when tetanus and diphtheria protection is required
during pregnancy. In some situations*, healthcare providers can choose to
administer Tdap instead of Td to add protection against pertussis. When Td
or Tdap is administered during pregnancy, the second or third trimester is
preferred.
Providers who choose to administer Tdap to pregnant women should discuss
the lack of data with the pregnant women and are encouraged to report Tdap
administrations regardless of the trimester, to the appropriate manufacturer
's pregnancy registry: for Boostrix® to GlaxoSmithKline Biologicals at 1
-888-825-5249, or for Adacel®, to sanofi pasteur at 800-822-2463.
Situations with increased risk for pertussis: Healthcare providers can
choose to administer Tdap instead of Td to protect against pertussis in
pregnant adolescents for routine or "catch-up" vaccination because the
incidence of pertussis is high among adolescents, in pregnant healthcare
personnel and child care providers to prevent transmission to infants
younger than 12 months of age and to other vulnerable persons, and in
pregnant women employed in an institution or living in a community with
increased pertussis activity.
总的意思就是孕妇可以安全使用DTaP，但是由于缺少数据不推荐使用。（http://www.cdc.gov/vaccines/pubs/preg-guide.htm#tdap）。
精华贴，是这样说的：
DTaP在孕妇中没有很多安全和有效性数据，所以如果选择请慎重考虑。CDC是这样建议
的：
Pregnancy is not a contraindication for use of Tdap. Data on safety,
immunogenicity and the outcomes of pregnancy are not available for pregnant
women who receive Tdap.When Tdap is administered during pregnancy,
transplacental maternal antibodies might protect the infant against
pertussis in early life. They also could interfere with the infant's immune
response to infant doses of DTaP, and leave the infant less well protected
against pertussis.
ACIP recommends Td when tetanus and diphtheria protection is required
during pregnancy. In some situations*, healthcare providers can choose to
administer Tdap instead of Td to add protection against pertussis. When Td
or Tdap is administered during pregnancy, the second or third trimester is
preferred.
Providers who choose to administer Tdap to pregnant women should discuss
the lack of data with the pregnant women and are encouraged to report Tdap
administrations regardless of the trimester, to the appropriate manufacturer
's pregnancy registry: for Boostrix® to GlaxoSmithKline Biologicals at 1
-888-825-5249, or for Adacel®, to sanofi pasteur at 800-822-2463.
Situations with increased risk for pertussis: Healthcare providers can
choose to administer Tdap instead of Td to protect against pertussis in
pregnant adolescents for routine or "catch-up" vaccination because the
incidence of pertussis is high among adolescents, in pregnant healthcare
personnel and child care providers to prevent transmission to infants
younger than 12 months of age and to other vulnerable persons, and in
pregnant women employed in an institution or living in a community with
increased pertussis activity.
总的意思就是孕妇可以安全使用DTaP，但是由于缺少数据不推荐使用。（http://www.cdc.gov/vaccines/pubs/preg-guide.htm#tdap）。
