there was a study in ~2004 saying aspirin users had a higher chance of low
B12 levels, but other studies cannot replicate the results.
there is also no known mechanism for aspirin to interfere with B12
metabolism.
aspirin is known to reduce absorption and increase excretion of vit C and
folic acid. but for the majority in a modern society, this has no impact
because of the much more than sufficient supply of vit C and folic acid in
food. for the vulnerable ones though, this can be a problem, sometimes big.