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SHH: A Morphogen and Axonal Guidance Cue
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SHH: A Morphogen and Axonal Guidance Cue# Biology - 生物学
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MCBJC Discussion for the week of 4/21
Sonic Hedgehog: A Morphogen and Axonal Guidance Cue
Hedgehog is probably the most well-known morphogen in embryo development. As a
multifunctional molecule involved in cell differentiation, cell proliferation
and tissue patterning, hedgehog's functions as a morphogen have been
extensively studied. However, recent studies about another morphogen - BMP
family revealed its involvement in repelling spinal cord commissural axons.
Thus the possibility that Sonic H
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