If it were 15 years ago, your thought might lead you somewhere substantial,
i.e. being a successful PI in a decent institute. However, we are in year
2012. There are 1000+ labs actively in solving structures in the world. X-
ray crystallography is so mature that anyone of them can solve important
targets on yearly basis. Let alone EM is catching up and NMR steals a small
slice. By the time you are ready to do something, all the low hanging fruits
are gone and the entry barrier to any specific fields is too high.
However, the above-mentioned problem is not most worrisome one. There will
simply be not many positions (faculty or industry) available for x-ray
crystallographers, while there will be more x-ray crystallographers floating
around. I can bet my money on this statement.
Why bother? Or at least be cautious.