avatar
l*d
2
刚看到的,不知道是不是真的?确定了吗?
avatar
A*y
4
We are going over the cliff because Republican won't even increase marginal
rate of people who made over 400k and won't cut any defense budget (go read
the news if you don't know what I'm talking about). Yes, it will mean there
will be no funding for any new NIH grant because 80% of the budget is for
the continuation of existing grants.
avatar
a*2
6
Good for future generations. They won't jump into this bio black hole.
avatar
b*8
8
如果NIH不commit新的grant的话,那大家就都不用写proposal了?

marginal
read
there

【在 A******y 的大作中提到】
: We are going over the cliff because Republican won't even increase marginal
: rate of people who made over 400k and won't cut any defense budget (go read
: the news if you don't know what I'm talking about). Yes, it will mean there
: will be no funding for any new NIH grant because 80% of the budget is for
: the continuation of existing grants.

avatar
K*S
9
no wonder so many faculty and phd voted for OBAMA, the tax increased is only
enough for 8-9 days of government spending. Without serious spending cut,
the whole country is going down. Who cares about NIH if that really happens.

marginal
read
there

【在 A******y 的大作中提到】
: We are going over the cliff because Republican won't even increase marginal
: rate of people who made over 400k and won't cut any defense budget (go read
: the news if you don't know what I'm talking about). Yes, it will mean there
: will be no funding for any new NIH grant because 80% of the budget is for
: the continuation of existing grants.

avatar
S*e
10
其实应该砍钱的不只nih, 国防部,老兵部都有大量的钱投在生物里。而且相当一部分
类似于nih内部的钱,很是浪费,又不出产什么东西。政府真的应该大量削减这些不必
要的开销了

only
happens.

【在 K******S 的大作中提到】
: no wonder so many faculty and phd voted for OBAMA, the tax increased is only
: enough for 8-9 days of government spending. Without serious spending cut,
: the whole country is going down. Who cares about NIH if that really happens.
:
: marginal
: read
: there

avatar
j*h
11
相对于那些乱七八糟的钱,比如说给老黑劳模看病生孩子section8粮食券,NIH
extramural的这点屁钱简直是九牛一毛。这还要砍,简直是鼠目寸光。
avatar
b*n
12
知识分子和老黑老墨,哪个好欺负?
“小知识分子阶级的局限性”

【在 j********h 的大作中提到】
: 相对于那些乱七八糟的钱,比如说给老黑劳模看病生孩子section8粮食券,NIH
: extramural的这点屁钱简直是九牛一毛。这还要砍,简直是鼠目寸光。

avatar
K*S
13
Politician never cares about the country. They only care about votes.

【在 j********h 的大作中提到】
: 相对于那些乱七八糟的钱,比如说给老黑劳模看病生孩子section8粮食券,NIH
: extramural的这点屁钱简直是九牛一毛。这还要砍,简直是鼠目寸光。

avatar
A*y
14
If you actually believe that we have a debt problem, it is going to be a
long discussion. Republican cannot even pass their own plan B bill. Also,
the other bill passed Congress only cut around 250 billion without a single
cent from defense. The senate bill which already passed (yes passed by the
senate already) is far more balanced. Republican seems to ignore the fact
that there is a complete budget bill PASSED by the senate. I will let you
guys know if the NIH is not funding my RO1 due to budget that is way below
payline.

only
happens.

【在 K******S 的大作中提到】
: no wonder so many faculty and phd voted for OBAMA, the tax increased is only
: enough for 8-9 days of government spending. Without serious spending cut,
: the whole country is going down. Who cares about NIH if that really happens.
:
: marginal
: read
: there

avatar
y*8
15
If you do NOT believe that we have a debt problem, I am speechless.
Debt problem does not mean that USA will bankrupt. Instead, it only means
that government have taken more money from people than it deserved. People
have to pay either directly by taxation, or indirectly by inflation.
Just talking about R01, which has been devalued by the debt problem. The
size of R01 has been stabilized for two decades. Then, one R01 provided
sufficient fund for a mid-sized lab ;now, two R01s are minimal to maintain a
lab running in a medical-school setting.

,
single
the
fact

【在 A******y 的大作中提到】
: If you actually believe that we have a debt problem, it is going to be a
: long discussion. Republican cannot even pass their own plan B bill. Also,
: the other bill passed Congress only cut around 250 billion without a single
: cent from defense. The senate bill which already passed (yes passed by the
: senate already) is far more balanced. Republican seems to ignore the fact
: that there is a complete budget bill PASSED by the senate. I will let you
: guys know if the NIH is not funding my RO1 due to budget that is way below
: payline.
:
: only

avatar
A*y
16
Do you have a economic or MBA degree? Did you sold all your stock and short
the market in 2008? Did you brought gold at 300/oz and told people not to
chase at 1700/oz? If you didn't, I don't even want to debate with you about
US debt structure. Although I'm in science, I have dual diploma (yes, not
the common double major which you get one diploma; I received two) and one
of them is in Economics (lowest GPA 3.7 on finance because I was arguing
with my professor on the role of Fed and what eventually occurred in 2008 in
the late 90s).

a

【在 y******8 的大作中提到】
: If you do NOT believe that we have a debt problem, I am speechless.
: Debt problem does not mean that USA will bankrupt. Instead, it only means
: that government have taken more money from people than it deserved. People
: have to pay either directly by taxation, or indirectly by inflation.
: Just talking about R01, which has been devalued by the debt problem. The
: size of R01 has been stabilized for two decades. Then, one R01 provided
: sufficient fund for a mid-sized lab ;now, two R01s are minimal to maintain a
: lab running in a medical-school setting.
:
: ,

avatar
y*8
17
I am surprised by your arrogance, economist.
Do you want to post your full transcript on the biology board?

short
to
about
not
in

【在 A******y 的大作中提到】
: Do you have a economic or MBA degree? Did you sold all your stock and short
: the market in 2008? Did you brought gold at 300/oz and told people not to
: chase at 1700/oz? If you didn't, I don't even want to debate with you about
: US debt structure. Although I'm in science, I have dual diploma (yes, not
: the common double major which you get one diploma; I received two) and one
: of them is in Economics (lowest GPA 3.7 on finance because I was arguing
: with my professor on the role of Fed and what eventually occurred in 2008 in
: the late 90s).
:
: a

avatar
A*y
18
Who cares? You don't have to believe in me. It is your money not mine. I
actually want the government to go over the cliff.

【在 y******8 的大作中提到】
: I am surprised by your arrogance, economist.
: Do you want to post your full transcript on the biology board?
:
: short
: to
: about
: not
: in

avatar
K*S
19
LOL, even obama himself doesn't dare to say US doesn't have a debt problem.
I'm totally speechless. Under tough economy, everyone will suffer. Why can't
NIH's budget be cut? If they do cut defense budget, what do you think DOD
will cut first? funding for drones or funding for basic biomedical research?
If you want to talk about politics, there are other sections to discuss.
I don't want to waste time here.

,
single
the
fact

【在 A******y 的大作中提到】
: If you actually believe that we have a debt problem, it is going to be a
: long discussion. Republican cannot even pass their own plan B bill. Also,
: the other bill passed Congress only cut around 250 billion without a single
: cent from defense. The senate bill which already passed (yes passed by the
: senate already) is far more balanced. Republican seems to ignore the fact
: that there is a complete budget bill PASSED by the senate. I will let you
: guys know if the NIH is not funding my RO1 due to budget that is way below
: payline.
:
: only

avatar
y*8
20
I did not have much money to worry about, then. If I had concerns of money,
I probably would not choose biology from the beginning.
BTW, don't worry too much about your R01 application. NIH will cut 10% of
all funded projects to make the space for the new ones.

【在 A******y 的大作中提到】
: Who cares? You don't have to believe in me. It is your money not mine. I
: actually want the government to go over the cliff.

avatar
A*y
21
Probably, it also depending on the each NIH institution. Don't forget NIH
and NCI are the only two directors who are directly appointed by the POTUS.

,

【在 y******8 的大作中提到】
: I did not have much money to worry about, then. If I had concerns of money,
: I probably would not choose biology from the beginning.
: BTW, don't worry too much about your R01 application. NIH will cut 10% of
: all funded projects to make the space for the new ones.

avatar
y*8
22
Basic science is what a government should invest on, because it would not
generate foreseeable profit.
For the rest of what NIH is spending on, private section would have done
much better for the same amount of money.
Unfortunately, pure basic science only accounts for about 20% of research
budget from public funding, and it is the least concern of politicians.

.
't
research?

【在 K******S 的大作中提到】
: LOL, even obama himself doesn't dare to say US doesn't have a debt problem.
: I'm totally speechless. Under tough economy, everyone will suffer. Why can't
: NIH's budget be cut? If they do cut defense budget, what do you think DOD
: will cut first? funding for drones or funding for basic biomedical research?
: If you want to talk about politics, there are other sections to discuss.
: I don't want to waste time here.
:
: ,
: single
: the

avatar
m*5
23
用那个链接appeal 了,希望有点用
avatar
a*2
24
Totally agree. When economics sucks, everyone should sacrifice, some more
than others. NIH, especially pure basic science research part, of course
should be cut first. There is even no need to debate about it.

.
't
research?

【在 K******S 的大作中提到】
: LOL, even obama himself doesn't dare to say US doesn't have a debt problem.
: I'm totally speechless. Under tough economy, everyone will suffer. Why can't
: NIH's budget be cut? If they do cut defense budget, what do you think DOD
: will cut first? funding for drones or funding for basic biomedical research?
: If you want to talk about politics, there are other sections to discuss.
: I don't want to waste time here.
:
: ,
: single
: the

avatar
b*k
25
越是经济不行的时候越要政府支持R&D,因为private sector这时候保命要紧没人去做长
线投资了。There is even no need to debate about it, lol

【在 a**********2 的大作中提到】
: Totally agree. When economics sucks, everyone should sacrifice, some more
: than others. NIH, especially pure basic science research part, of course
: should be cut first. There is even no need to debate about it.
:
: .
: 't
: research?

avatar
y*8
26
R only.
D is not "长线投资".

【在 b******k 的大作中提到】
: 越是经济不行的时候越要政府支持R&D,因为private sector这时候保命要紧没人去做长
: 线投资了。There is even no need to debate about it, lol

avatar
a*2
27
But not basic science research in bio field, it's too far away from
profitable. Translational research is an exception.

【在 b******k 的大作中提到】
: 越是经济不行的时候越要政府支持R&D,因为private sector这时候保命要紧没人去做长
: 线投资了。There is even no need to debate about it, lol

avatar
b*k
28
你仔细想想你这条论断是因为生物真的没有profitability,还是因为你学了生物而且
很苦逼?

【在 a**********2 的大作中提到】
: But not basic science research in bio field, it's too far away from
: profitable. Translational research is an exception.

avatar
a*k
29
D is already long term for many companies/private sections.

【在 y******8 的大作中提到】
: R only.
: D is not "长线投资".

avatar
y*8
30
Everyone is suffering, but no one should sacrifice.
Calling other people to sacrifice is not ethical.

【在 a**********2 的大作中提到】
: Totally agree. When economics sucks, everyone should sacrifice, some more
: than others. NIH, especially pure basic science research part, of course
: should be cut first. There is even no need to debate about it.
:
: .
: 't
: research?

avatar
y*8
31
When people decide to do D, there is foreseeable profit.
For R, it is like throwing the dice.
There are different types of companies investing on different stages.

【在 a********k 的大作中提到】
: D is already long term for many companies/private sections.
avatar
y*8
32
Asking for profitable research is bizarre in Science.
Doing basic research is a welfare for a civilized society, just like
humanity. It is a long-term investment with return in decades, or even in
generations.
It also has been kept as minimum as <1% of government spending and <0.2% of
US GDP.
In contrast, NIH's "Translational research" will be a big waste of money.
If the healthcare industry see the profit coming, it will jump on the real
Translational research, even without the money from NIH.

【在 a**********2 的大作中提到】
: But not basic science research in bio field, it's too far away from
: profitable. Translational research is an exception.

avatar
a*k
33
translational research is still research.
most translational research projects are aiming for return after decades...
It is bizarre to see people bashing application reserach while bluffing
basic research

of

【在 y******8 的大作中提到】
: Asking for profitable research is bizarre in Science.
: Doing basic research is a welfare for a civilized society, just like
: humanity. It is a long-term investment with return in decades, or even in
: generations.
: It also has been kept as minimum as <1% of government spending and <0.2% of
: US GDP.
: In contrast, NIH's "Translational research" will be a big waste of money.
: If the healthcare industry see the profit coming, it will jump on the real
: Translational research, even without the money from NIH.

avatar
y*8
34
I am totally fine with real translational research.
But please, don't ask the public to fund it.

【在 a********k 的大作中提到】
: translational research is still research.
: most translational research projects are aiming for return after decades...
: It is bizarre to see people bashing application reserach while bluffing
: basic research
:
: of

avatar
y*8
35
Could you please quote my words, which were "bashing application reserach"?

【在 a********k 的大作中提到】
: translational research is still research.
: most translational research projects are aiming for return after decades...
: It is bizarre to see people bashing application reserach while bluffing
: basic research
:
: of

avatar
b*k
36
这个我不同意哈 之所以提translational无非是因为从lab finding到market之间的
death of valley太恐怖,让药厂也好VC也好去填这个坑他们吃不消,所以得靠政府的
钱。其实本质上这部分也是R,因为不确定性和风险。

【在 y******8 的大作中提到】
: I am totally fine with real translational research.
: But please, don't ask the public to fund it.

avatar
y*8
37
I know the "death valley" between B2B.
However, forcing basic researchers into translational research may not be
the right strategy.
As you said, even the pharms and VCs cannot afford it, which overall R&D
budget triple the government R&D funding in US. So, will the government fund
be enough, or even good in nature?
I think people should be patient, let the Science flow. The "death valley"
will be filled one day much easier than now.

【在 b******k 的大作中提到】
: 这个我不同意哈 之所以提translational无非是因为从lab finding到market之间的
: death of valley太恐怖,让药厂也好VC也好去填这个坑他们吃不消,所以得靠政府的
: 钱。其实本质上这部分也是R,因为不确定性和风险。

avatar
b*k
38
我不是说应该强迫科学家去做translational,而是说translational的研究也应该得到
政府资助,其实原因就一个:政府不资助就没人搞了。和政府要投资做基础研究的理由
一样。
至于政府有没有这么多钱。我的理解是这样:政府不应该,也没有必要全程资助
translational research(这个和basic science不一样),但是政府可以扮演类似
angel的作用。在基础研究转化的极早期,也是风险最大的时候给资助,也不需要那么
多钱。一旦看到成功苗头,就是VC该进入的时候了。为了justify政府的投入,甚至政
府投资算是入股,VC进入的时候可以退出我看也行
NIH搞得哪个SBIR其实就有点这个意思。不过SBIR大家似乎都觉得很不靠谱,不知道是
什么原因?内行可以来指教下

fund

【在 y******8 的大作中提到】
: I know the "death valley" between B2B.
: However, forcing basic researchers into translational research may not be
: the right strategy.
: As you said, even the pharms and VCs cannot afford it, which overall R&D
: budget triple the government R&D funding in US. So, will the government fund
: be enough, or even good in nature?
: I think people should be patient, let the Science flow. The "death valley"
: will be filled one day much easier than now.

avatar
d*n
39
I completely agree with you. everyone should suffer.
To be fair, every budget should be cut to the same extent.
But it is bad politics since everyone will hate you.

.
't
research?

【在 K******S 的大作中提到】
: LOL, even obama himself doesn't dare to say US doesn't have a debt problem.
: I'm totally speechless. Under tough economy, everyone will suffer. Why can't
: NIH's budget be cut? If they do cut defense budget, what do you think DOD
: will cut first? funding for drones or funding for basic biomedical research?
: If you want to talk about politics, there are other sections to discuss.
: I don't want to waste time here.
:
: ,
: single
: the

avatar
y*s
40
Cash flow is most important for running a business and for running a
government. If tomorrow is the end of the world, why do you want to spend
money for the day after tomorrow?
avatar
y*8
41
不知道公司怎么样,医学院/医院都动用很大的资源进行translational research.
做纯粹的translational research对于scientists吸引力不大。Top scientist很少只
做translational research的。
首先,发的文章IF不会很高。和基础研究比,原创性不够。和临床研究比,一般也不会
是首个病例报道。
其次,技术上也不会很fancy。
Translational research要基于坚实的基础研究发现和普遍检验的技术。做
Translational research的人要具备的是了解临床服务的直接需要,准确判断基础研究
结果的,和正确选择技术设备。
当然Translational research也会失败。但是当医院动用自己的内部资金作
Translational research时,都是会有选择的。对于高难度的项目,医院只有存在盈余
时才会试。当然如果NIH提供free money,医院不会再有什么顾虑的。

【在 b******k 的大作中提到】
: 我不是说应该强迫科学家去做translational,而是说translational的研究也应该得到
: 政府资助,其实原因就一个:政府不资助就没人搞了。和政府要投资做基础研究的理由
: 一样。
: 至于政府有没有这么多钱。我的理解是这样:政府不应该,也没有必要全程资助
: translational research(这个和basic science不一样),但是政府可以扮演类似
: angel的作用。在基础研究转化的极早期,也是风险最大的时候给资助,也不需要那么
: 多钱。一旦看到成功苗头,就是VC该进入的时候了。为了justify政府的投入,甚至政
: 府投资算是入股,VC进入的时候可以退出我看也行
: NIH搞得哪个SBIR其实就有点这个意思。不过SBIR大家似乎都觉得很不靠谱,不知道是
: 什么原因?内行可以来指教下

avatar
I*2
42
认识的许多教授都选了08。。现在要哭死了
avatar
N2
43
也就是说要砍8% 左右? 每年是31B, 根据NIH

【在 l***d 的大作中提到】
: 刚看到的,不知道是不是真的?确定了吗?
avatar
k*a
44
You are going to be transferred to a NON-tenure track AP position soon.

,
single
the
fact

【在 A******y 的大作中提到】
: If you actually believe that we have a debt problem, it is going to be a
: long discussion. Republican cannot even pass their own plan B bill. Also,
: the other bill passed Congress only cut around 250 billion without a single
: cent from defense. The senate bill which already passed (yes passed by the
: senate already) is far more balanced. Republican seems to ignore the fact
: that there is a complete budget bill PASSED by the senate. I will let you
: guys know if the NIH is not funding my RO1 due to budget that is way below
: payline.
:
: only

avatar
k*a
45
What the fuck are you talking about? Deserved? Nobody deserves anything in
the world. One RO1 is enough to run a small lab you idiot!

a

【在 y******8 的大作中提到】
: If you do NOT believe that we have a debt problem, I am speechless.
: Debt problem does not mean that USA will bankrupt. Instead, it only means
: that government have taken more money from people than it deserved. People
: have to pay either directly by taxation, or indirectly by inflation.
: Just talking about R01, which has been devalued by the debt problem. The
: size of R01 has been stabilized for two decades. Then, one R01 provided
: sufficient fund for a mid-sized lab ;now, two R01s are minimal to maintain a
: lab running in a medical-school setting.
:
: ,

avatar
k*a
46
How did you get your degrees? You misspell everything and your grammar is
terrible.

short
to
about
not
in

【在 A******y 的大作中提到】
: Do you have a economic or MBA degree? Did you sold all your stock and short
: the market in 2008? Did you brought gold at 300/oz and told people not to
: chase at 1700/oz? If you didn't, I don't even want to debate with you about
: US debt structure. Although I'm in science, I have dual diploma (yes, not
: the common double major which you get one diploma; I received two) and one
: of them is in Economics (lowest GPA 3.7 on finance because I was arguing
: with my professor on the role of Fed and what eventually occurred in 2008 in
: the late 90s).
:
: a

avatar
A*y
47
I don't know. I guess English is not that important at answering questions
correctly on the exam or filling out accounting balance sheet. If you are a
professor, maybe you should grade your chemistry/biology exam based on
students' English ability. Let me know how that turn out for you.
As for the tenure thingy, I'm in a medical school. Tenure means little if I
don't have money. I know my Chairman will fire me if I don't bringing
grant, playing politic just completely waste of time without money to back
it up. I think my Chairman is more worry about me leaving taking my money,
since I think he short changed me on my start-up.
Btw, if my English is that horrible, and you have to read it. Maybe you
should spend some time telling me where my mistakes are. I'm open to
criticism anytime.

【在 k****a 的大作中提到】
: How did you get your degrees? You misspell everything and your grammar is
: terrible.
:
: short
: to
: about
: not
: in

avatar
A*y
48
NIGMS new grant are facing a >20% cut. If you use modular budget, you will
be lucky to get 200k direct (the PI I know only got 190k). Assuming you put
yourself at 50% if you are in a medical school. That's 50k-60k out of the
door. A post-doc is around another 55k including all the benefit that you
have to pay (H1b prevailing wage for a fresh Ph.D. is 41,900 in my field). A
graduate student is another 28-30k. If you want to hire a tech, you will
have no money left. Do you consider a post-doc and an graduate student a
small lab or even functional lab?

【在 k****a 的大作中提到】
: What the fuck are you talking about? Deserved? Nobody deserves anything in
: the world. One RO1 is enough to run a small lab you idiot!
:
: a

avatar
y*s
49
Forgive my crappy English
If you post in English, everybody assumes you know when to use do/did/does/
done, a/an, on/in/about/for/of and things like those.
rule of thumb: It is your own responsibility to make corrections. Being born
ugly is not your fault, but it is a crime to stand up and freak out people.
..

questions
a
I
,

【在 A******y 的大作中提到】
: I don't know. I guess English is not that important at answering questions
: correctly on the exam or filling out accounting balance sheet. If you are a
: professor, maybe you should grade your chemistry/biology exam based on
: students' English ability. Let me know how that turn out for you.
: As for the tenure thingy, I'm in a medical school. Tenure means little if I
: don't have money. I know my Chairman will fire me if I don't bringing
: grant, playing politic just completely waste of time without money to back
: it up. I think my Chairman is more worry about me leaving taking my money,
: since I think he short changed me on my start-up.
: Btw, if my English is that horrible, and you have to read it. Maybe you

avatar
w*r
50
美国在超乎异常的速度印钱,缺德不是钱,而是好的制度来让钱有用,花在游艇和大飞机
和福利的无所谓花费一年可以支持nih 几百年.好比,沙漠缺水,控制植物
的用水而加大人畜的用水,只会让沙漠化更严重.
avatar
o*a
51
If this cut directly goes to RO1 money, everyone will feel the consequence.
Why not the hell to increase taxation on the high incomes ?

【在 l***d 的大作中提到】
: 刚看到的,不知道是不是真的?确定了吗?
avatar
a*2
52
From the researchers' standpoint, you don't want to see nih funding cut. But
if you look at this as an outsider, definitely nih basic science research
funding should be cut first before anything else, including nasa, welfare,
medicare, medicaid,etc.

【在 w********r 的大作中提到】
: 美国在超乎异常的速度印钱,缺德不是钱,而是好的制度来让钱有用,花在游艇和大飞机
: 和福利的无所谓花费一年可以支持nih 几百年.好比,沙漠缺水,控制植物
: 的用水而加大人畜的用水,只会让沙漠化更严重.

avatar
t*o
53
why is that?

But

【在 a**********2 的大作中提到】
: From the researchers' standpoint, you don't want to see nih funding cut. But
: if you look at this as an outsider, definitely nih basic science research
: funding should be cut first before anything else, including nasa, welfare,
: medicare, medicaid,etc.

avatar
a*2
54
If you look at it as an outsider, obviously other stuff are more important
than basic science research and more closely related to our daily life.

【在 t*******o 的大作中提到】
: why is that?
:
: But

avatar
t*o
55
看过几十年前NASA的哥们写给修女的故事吗?你现在的境界也就和那个非洲修女差不多
。要是没看到,以下是链接,http://select.yeeyan.org/view/265546/309669

【在 a**********2 的大作中提到】
: If you look at it as an outsider, obviously other stuff are more important
: than basic science research and more closely related to our daily life.

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