Looking for【(Sr.)Director, in vitro Pharmacology】for a leading CRO in Shanghai
Looking for【(Sr.)Director, in vitro Pharmacology】for a leading CRO in Shanghai# Biology - 生物学
t*u
1 楼
感觉用起来有点慢 值得升级内存么?
J*S
2 楼
Pls contact : d******[email protected] for more information Report to: Head of in vitro Biology Description: Looking for a highly experienced and motivated Scientist with a strong cellular and molecular pharmacology background to lead the In Vitro Pharmacology group. The successful candidate will play a leadership role in the company including building up an internal team, leading projects in a multidisciplinary team, as well as efficiently interacting with clients to drive project success. The candidate will play a key role in the selection of lead compounds by designing and implementing cell-based assays across multiple disease areas including oncology, CNS, and inflammation. Will perform mechanism-of-action studies and investigate molecular signaling pathways downstream of drug-target interaction using a variety of in vitro/ ex vivo techniques and is expected to manage multiple projects. The candidate is expected to develop deep understanding of target and disease biology and will have significant input into target evaluation, assay selection, and lead identification. Willingness to certain amount of hands on work is required to ensure highest quality of research activity moving forward. Will work closely with the Chemistry and ADME/PK Departments to identify the best drug candidates. Qualifications: • PhD in biochemistry, cell biology, pharmacology or related areas • 8-12 years of experience in biotechnology or pharmaceutical industry with expertise in in vitro pharmacology • Strong expertise in a variety of functional assays and how the assays support in vivo pharmacology and preclinical development • Successful track record in identifying hits/leads that lead to drug candidates in functional and biochemical assays • Solid understanding of oncology, CNS disorders, and immune diseases • Broad knowledge of assay technology and assays types a must • In depth knowledge of GPCR, NHR, ion channel biology a must • Knowledge of instrumentation, equipment automation, and HTS highly desirable • Experience in managing projects and people, including PhD scientists • Willing to take initiative in finding creative solutions for complex problems • Analytical, organized, efficient, detail-oriented and goal-driven • Independent yet enjoys collaborative problem-solving • Excellent communication, documentation and time management skills required • Desire to take on challenges and grow professionally in a fast-paced , dynamic multidisciplinary environment • Proven ability to direct large research teams, including providing sound scientific direction, leading scientific discourse, and motivating teams