BAC library control for chromosome conformation capture# Biology - 生物学
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在帮忙审一篇文章. 两个人打架,对chromosome conformation capture是否一定需要
BAC library control纠缠不休。
一个说3C实验一定要有BAC Library to control random chromatin collisions和
digestion efficiency.另外一个说3C实验里有几对control primers不仅覆盖了anchor
区域,也包括anchor surrounding region as a control.所以可以替代BAC library,
还给出了几篇文献
哪个说的对?
BAC library control纠缠不休。
一个说3C实验一定要有BAC Library to control random chromatin collisions和
digestion efficiency.另外一个说3C实验里有几对control primers不仅覆盖了anchor
区域,也包括anchor surrounding region as a control.所以可以替代BAC library,
还给出了几篇文献
哪个说的对?