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Number and activity of E3# Biology - 生物学
f*h
1
我的EB1A i-140是e-file 到TSC批的.现在不在TSC的辖区工作了.
准备file I-485, 请问下面的两个地址,哪一个是正确的?
地址1:来源于网友模板
USCIS
Texas Service Center
P.O. Box 851391
Mesquite, TX 75185-1391
地址2:来源与USCIS网站
USCIS Texas Service Center
P.O. Box 852135
Mesquite, TX 75185
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s*9
2
When people say there are hundreds E3 in the proteome, do they know each and
every one in these hundreds has proven activity
towards some sort of substrate? Otherwise where does this number (~ one
thousand or some say ~600) come from?
Also,
For SCF, people say there are hundreds of them, do they know experimentally
the S, C, and F of each SCF? otherwise where does
this number (few hundres SCF) come from? (Is it the theoretical combinations
of all S,C,F?)
The same question of CRL. Do they know the C and R and other components of
these complexes?
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m*n
3
i sent to box 660867
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s*y
4
纯属理论预测。根据有多少个F-box protein之类的算出来的

and
experimentally
combinations

【在 s********9 的大作中提到】
: When people say there are hundreds E3 in the proteome, do they know each and
: every one in these hundreds has proven activity
: towards some sort of substrate? Otherwise where does this number (~ one
: thousand or some say ~600) come from?
: Also,
: For SCF, people say there are hundreds of them, do they know experimentally
: the S, C, and F of each SCF? otherwise where does
: this number (few hundres SCF) come from? (Is it the theoretical combinations
: of all S,C,F?)
: The same question of CRL. Do they know the C and R and other components of

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s*9
5
thanks, any chance you know any reference?

【在 s*********y 的大作中提到】
: 纯属理论预测。根据有多少个F-box protein之类的算出来的
:
: and
: experimentally
: combinations

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S*r
6
1. 有RING domain的被假定为E3,通过genome wide search
2. 能autoubiquitylation的被认为是E3
3. 很多E3还没有发现substrate
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