T*I
2 楼
一个对照性的microarray实验有1500个基因, 我没有用FDR曲线Q值,而是另行设计了一
个新的选法,第一次选出了64个, 第二次从64个中选出44个, 然后再选出29个, 最后一
步选出了19个。这样选出的结果以1500为基数的话,在纯粹的数量上是多了还是少了?谢
谢。
个新的选法,第一次选出了64个, 第二次从64个中选出44个, 然后再选出29个, 最后一
步选出了19个。这样选出的结果以1500为基数的话,在纯粹的数量上是多了还是少了?谢
谢。
e*m
3 楼
啥时候都可以,但是每个卡能兑换的不完全一样,forward能换amazon
但不知道是不是1w换100,所有thankyou卡都可以
但不知道是不是1w换100,所有thankyou卡都可以
G*n
4 楼
depends on your biology... for RNAseq, we usually assume 250~500 out of
25000, 1% to 2%. What array are you using? Why 1500 genes?
25000, 1% to 2%. What array are you using? Why 1500 genes?
y*j
5 楼
你需要一张thankyou的卡
然后转刀thankyou里面换救醒。
然后转刀thankyou里面换救醒。
G*n
8 楼
1%左右差不多。你要是用qvalue选出来多少?
T*I
10 楼
None of them can be selected by the FDR curve and q-value after permutation.
But with the raw p-values to fit the FDR and Q-value, 5 only.
An interesting thing is that if the selection is at the 0.01 with the new
method, only 5 can be selected, but these 5 genes are not the 5 genes
selected by the above. Only 3 are the same. The other 2 in the new method
even have the raw p-values > 0.05 in the old method.
In addition, in the 19 genes selected by the new method, 8 or more than 42%
of them have the raw p-values > 0.05 in the old method. So, you can see the
new method is significantly different from the current one.
【在 G******n 的大作中提到】
: 1%左右差不多。你要是用qvalue选出来多少?
But with the raw p-values to fit the FDR and Q-value, 5 only.
An interesting thing is that if the selection is at the 0.01 with the new
method, only 5 can be selected, but these 5 genes are not the 5 genes
selected by the above. Only 3 are the same. The other 2 in the new method
even have the raw p-values > 0.05 in the old method.
In addition, in the 19 genes selected by the new method, 8 or more than 42%
of them have the raw p-values > 0.05 in the old method. So, you can see the
new method is significantly different from the current one.
【在 G******n 的大作中提到】
: 1%左右差不多。你要是用qvalue选出来多少?
G*n
12 楼
那差不多了,不知道你自己弄得这个方法是啥,不过你要是能保证false positive
rate收敛于你的cutoff就行了。关键还是去validation,那你弄的这19个,去单独做一
下,用普通ttest看看就知道了。
rate收敛于你的cutoff就行了。关键还是去validation,那你弄的这19个,去单独做一
下,用普通ttest看看就知道了。
n*9
13 楼
申 一张thank u prefered,随时1W->100$
b*1
16 楼
其实换了Bestbuy gift card再去bestbuy 买amaozn kindle gift card就好了常年
10000 for $100
10000 for $100
i*l
19 楼
为什么我的常年amazon 2500-> 25$, 5000-> 50$, 10000->100$
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