聚焦学术前沿，79项最新科学研究即将公布，2023 ESC热点抢鲜看！

EMPEROR - Empagliflozin in Patients with Chronic Heart Failure

EMPEROR试验：恩格列净在慢性心力衰竭患者中的应用

Renal Outcomes in PARAGLIDE-HF and PARAGON-HF

PARAGLIDE-HF和PARAGON-HF试验的肾脏结局

Effects of Dapagliflozin in Patients with Heart Failure and Deterioration of Kidney Function Below eGFR 25ml/min/1.73m²

达格列净用于心力衰竭合并肾功能恶化eGFR＜25ml/min/1.73m²患者的疗效

STRONG-HF

STRONG-HF多中心前瞻性随机试验：高强度治疗 vs. 常规治疗用于心衰

OPT-PACE - Optimising therapy in patients with pacemakers

OPT-PACE试验：心脏起搏器患者的优化治疗

The ADVOR trial: update on renal interactions

ADVOR试验：肾脏相互作用的最新数据

Subsequent Pregnancies in Patients with a previous PPCM

既往围产期心肌病（PPCM）患者的再次妊娠

SCORE2-ASIA risk prediction algorithms

SCORE2-ASIA风险预测模型

Carbon Monoxide and Acute Cardiac Events

一氧化碳和急性心脏事件

POETry - Long-term outcome of nationwide clinical implementation of oral step-down antibiotic treatment for endocarditis

POETry试验：全国范围内实施口服降阶梯抗生素治疗心内膜炎的长期结果

The QUALIREHAB trial

QUALIREHAB试验

CIRCA-Progress - Atrial Fibrillation Progression after Cryoballoon or Radiofrequency Ablation

CIRCA-Progress：冷冻球囊或射频消融后的房颤进展

RATE-AF trial wearables study

RATE-AF试验-可穿戴设备研究

An Integrated analysis of patients with atrial fibrillation from the ENGAGE, ENTRUST, and ENVISAGE trials

ENGAGE、ENTRUST和ENVISAGE试验-对房颤患者的综合分析

Posterior wall isolation improves outcomes for persistent atrial fibrillation with rapid posterior wall activity: a CAPLA substudy

CAPLA子研究：后壁隔离可改善伴后壁快速活动的持续性房颤的结局

A DECAAF II subanalysis based on artificial intelligence

基于人工智能的DECAAF II子分析

MR-NEDA - Prognosis of mild to severe MR

MR-NEDA试验：轻度至重度二尖瓣反流（MR）的预后

INVICTUS program: Mortality in rheumatic heart disease

INVICTUS项目：风湿性心脏病的死亡率

Timing of intervention in patients with severe tricuspid regurgitation

重度三尖瓣反流患者的干预时机

Machine learning in aortic stenosis

机器学习在主动脉瓣狭窄中的应用

TEER versus mitral surgery: data from a nationwide analysis

二尖瓣缘对缘修复（TEER） vs. 二尖瓣手术：全国范围数据分析

Rosuvastatin versus atorvastatin treatment in LODESTAR trial

LODESTAR试验：瑞舒伐他汀 vs. 阿托伐他汀

BIOFLOW DAPT - Biodegradable polymer SES versus durable polymer ZES in HBR subjects with 1-month DAPT

BIOFLOW DAPT试验：接受1个月双联抗血小板治疗（DAPT）的高出血风险（HBR）受试者中，生物可降解聚合物西罗莫司洗脱支架（SES）和耐用聚合物佐他莫司药物洗脱支架（ZES）的比较

The GUIDE-DES Trial - QCA versus IVUS guidance for DES implantation

GUIDE-DES试验：定量冠状动脉造影（QCA） vs. 血管内超声（IVUS）指导药物洗脱支架（DES）置入

MRUSMI post-PCI - Post-PCI sonothrombolysis in STEMI patients with electrocardiographic no-reflow

MRUSMI post-PCI试验：心电图描记无复流的ST段抬高型心肌梗死（STEMI）患者经皮冠状动脉介入治疗（PCI）后超声溶栓治疗

SHARE trial: P2Y₁₂ Inhibitor Monotherapy vs DAPT After PCI

SHARE试验：PCI后P2Y₁₂抑制剂单药治疗 vs. DAPT

Economic burden of CVD in the EU

欧盟心血管疾病经济负担

MI-TRAJECTORY - Subsequent cardiovascular disease trajectories following myocardial infarction

MI-TRAJECTORY试验：心肌梗死后的后续心血管疾病轨迹

Loss of life expectancy after myocardial infarction

心肌梗死后预期寿命缩短

Impact of risk factors globally

全球风险因素的影响

NATURE-PARADOX: Naturally Randomized Trial of Titrating Cumulative Exposure to LDL to Solve the Prevention Paradox

NATURE-PARADOX试验：滴定低密度脂蛋白（LDL）累积暴露量以解决预防悖论的自然随机试验

INTERASPIRE: An international survey of secondary prevention of CVD

INTERASPIRE试验：心血管疾病二级预防的国际调查

CLEAR - Outcomes total events analysis

CLEAR Outcomes试验-总事件分析

OCEAN(a)-DOSE Extension

OCEAN(a)-DOSE扩展试验

CLEAR - Outcomes analysis by glycaemic status

CLEAR Outcomes试验-根据血糖状况分析

DANCAVAS - User-defined outcomes

DANCAVAS试验：使用者自定义结果

SS-AFRF - Shensong Yangxin capsule regulates persistent atrial fibrillation after RFCA

SS-AFRF试验：参松养心胶囊对心导管射频消融术（RFCA）后持续性房颤的调节作用

SurHyb Trial: Hybrid Ablation in Persistent Atrial Fibrillation

SurHyb试验：混合消融用于持续性房颤治疗

CRALAL: Addtional right atrial ablation after cryoablation for AF

CRALAL试验：房颤冷冻消融术后的附加右心房消融术

COMPARE CRYO - an RCT of PolarX vs. Arctic Front Cryo PVI with ICM endpoint assessment

COMPARE CRYO试验：使用植入式心电监测器（ICM）终点评估PolarX vs. Arctic Front冷冻肺静脉隔离（PVI）的随机对照试验

5 year results from the COMPARE-ABSORB trial

COMPARE-ABSORB试验的5年结果

Meta-analysis of iFR-SWEDEHEART and DEFINE FLAIR

iFR-SWEDEHEART和DEFINE FLAIR试验的荟萃分析

Three-year results of HOST-POLYTECH-ACS RCT comparing durable- vs. degradable-polymer DES

HOST-Polytech-ACS随机对照试验的3年结果：耐用聚合物 vs. 可降解聚合物DES

FLOWER MI - 3-year outcomes

FLOWER MI试验3年结果

Sex Differences in FFR- or IVUS-Guided PCI in the randomized FLAVOUR trial

FLAVOR随机试验中，血流储备分数（FFR）或IVUS指导PCI的性别差异

CAVA-ADHF - Ultrasound evaluation of the inferior vena cava

CAVA-ADHF试验：下腔静脉的超声评估

RASTAVI - renin-angiotensin system blocked following TAVI

RASTAVI试验：经导管主动脉瓣植入术（TAVI）后肾素-血管紧张素系统阻滞

EASE-TAVR - Management of Fluid Overload in Patients with Severe Aortic Stenosis

EASE-TAVR试验：重度主动脉瓣狭窄患者液体超负荷管理

ReDS-SAFE HF study: a randomized controlled clinical

ReDS-SAFE HF研究：一项随机对照临床研究

MESSAGE-HF: Telemonitoring after a recent heart failure admission

MESSAGE-HF试验：近期心力衰竭入院后的远程监测

DASE-AI: Detect Aortic Stenosis by Echo with Artificial Intelligence

DASE-AI试验：人工智能超声检测主动脉瓣狭窄

The randomized CENTURY Trial of medical treatment and PET guided interventions vs standard care in chronic CAD

CENTURY随机试验：慢性冠状动脉疾病（CAD）药物治疗和正电子发射断层扫描（PET）指导的干预 vs. 标准干预

OPERA - AI - reporting of handheld echocardiography in suspected heart failure

OPERA-AI：疑似心力衰竭的手持式超声心动图报告

Dan-NICAD 3 - The Danish study of Non-Invasive diagnostic testing In Coronary Artery Disease

Dan-NICAD 3研究：丹麦冠状动脉疾病非侵入性诊断检查研究

CAMAREC: Evaluating CMR for Predicting CAD in LV Dysfunction

CAMAREC试验：评估心脏磁共振成像（CMR）在左心室功能障碍患者中预测CAD的价值

The randomized TAVR-CMR trial

TAVR-CMR随机试验

Long-term Outcomes Following Left Atrial Appendage Occlusion with a Watchman Device: Outcomes from the National Cardiovascular Data Registry

使用Watchman装置左心耳封堵后的长期结果：国家心血管数据注册研究结果

VISION Cardiac Surgery Post-operative AF

VISION研究：心脏外科手术后房颤

AI on large data permitted a robust prediction model of SCD, and explains the predicted risk at the individual level

大数据上人工智能可以建立稳健的心脏性猝死（SCD）预测模型，并解释个人层面的预测风险

Characteristics and predictors of repeat ablation in patients with atrial fibrillation undergoing multiple ablation procedures in real-world clinical practice

真实世界的临床实践中，接受多次消融手术的房颤患者重复消融的特征和预测因素

GLORIA-AF Multimorbidity Phenotypes in AF

GLORIA-AF试验：房颤的多发病表型

EARLY-UNLOAD - Early left ventricular unloading after VA-ECMO

EARLY-UNLOAD试验：静脉-动脉体外膜肺氧合（VA-ECMO）后早期左心室卸荷

Evolocumab for cardiac allograft vasculopathy

依洛尤单抗治疗心脏移植血管病变

RESILIENCE: Primary Endpoint Results

RESILIENCE试验：主要终点结果

Clinical evidence for high-risk cardiovascular medical devices: A systematic evaluation of the CORE-MD Consortium

高危心血管医疗器械的临床证据：CORE-MD联盟的系统评估

LIGHT - Learning Implementation of Guideline-based decision support system for Hypertension Treatment

LIGHT试验：基于指南的高血压治疗决策支持系统的学习实施

ORION-8: Long-term efficacy and safety of twice-yearly inclisiran in high cardiovascular risk patients

ORION-8试验：每年两次的inclisiran在高心血管风险患者中的长期疗效和安全性

Muvalaplin, a Potent Small Molecule Inhibitor of Lipoprotein(a)

Muvalaplin，一种有效的脂蛋白(a)小分子抑制剂

LIBerate-HeFH - a novel PCSK9-inhibitor in heterozygous FH

LIBerate-HeFH：一种新型PCSK9抑制剂用于杂合子家族性高胆固醇血症（FH）

REMAIN-1: A phase 3 study of recaticimab monotherapy in dyslipidaemia

REMAIN-1试验：recaticimab单药治疗血脂异常的3期研究

Risk of incident heart failure in men and women

男性和女性发生心力衰竭的风险

Global Congestive Heart Failure Frailty Study

全球充血性心力衰竭虚弱研究

DIG-META: Digoxin in heart failure and atrial fibrillation

DIG-META试验：地高辛在心力衰竭合并房颤患者中的应用

RECORD MI: Heart Failure Complicating Acute Myocardial Infarction

RECORD MI试验：心力衰竭并发急性心肌梗死

DAPA-MI – rationale and innovative design for a registry-based randomised clinical trial

DAPA-MI试验：基于注册研究的随机临床试验的基本原理和创新设计

NOTION - The Nordic Aortic Valve Intervention Trial

NOTION试验：北欧主动脉瓣介入试验

RIVER: Rivaroxaban for Valvular Heart Disease and Atrial Fibrillation

RIVER试验：利伐沙班治疗心脏瓣膜病合并房颤

EXPLORER-CN - Efficacy and safety of mavacamten in Chinese adults with symptomatic obstructive hypertrophic cardiomyopathy

EXPLORER-CN试验：mavacamten在中国成人症状性梗阻性肥厚型心肌病（oHCM）患者中的疗效和安全性

VALOR-HCM 56 Week Long-term Extension Study in oHCM

VALOR-HCM 56周长期扩展研究：mavacamten用于oHCM患者的疗效