Re: 离子通道有什么好研究的?# Biology - 生物学
t*r
1 楼
Ion channel is very important for the cell to control its resting potential,
propogate of action potential, etc.
One major question in this field is what is the structural and functional
relationship of ionchannels. For example, it is relative clear that the voltage
sensor S4 is critical for voltage dependent response, but how it changes its
structure during depolarization and how it links to the opening of the channel
pore are still unclear. Not until recently ( crystalgraphy of K channels from
propogate of action potential, etc.
One major question in this field is what is the structural and functional
relationship of ionchannels. For example, it is relative clear that the voltage
sensor S4 is critical for voltage dependent response, but how it changes its
structure during depolarization and how it links to the opening of the channel
pore are still unclear. Not until recently ( crystalgraphy of K channels from