看到这篇文献的报道,似乎活体内肿瘤细胞和正常细胞吸收不同化学物质的功能差别可 能很大。既然如此,在原理上,对肿瘤的诊断并不是医学上的难点? Clin Cancer Res. 2010 May 15; 16(10): 2833. Near IR heptamethine cyanine dye-mediated cancer imaging. Fig1. Active uptake of hepatamethine cyanine dyes by human cancer cells but not normal cells in cultureClin Cancer Res. 2010 May 15; 16(10): 2833.
【在 m********8 的大作中提到】 : 看到这篇文献的报道,似乎活体内肿瘤细胞和正常细胞吸收不同化学物质的功能差别可 : 能很大。既然如此,在原理上,对肿瘤的诊断并不是医学上的难点? : Clin Cancer Res. 2010 May 15; 16(10): 2833. : Near IR heptamethine cyanine dye-mediated cancer imaging. : Fig1. Active uptake of hepatamethine cyanine dyes by human cancer cells but : not normal cells in cultureClin Cancer Res. 2010 May 15; 16(10): 2833.
m*8
5 楼
多谢了。
不少
【在 m*****u 的大作中提到】 : 这个不新鲜。也不一定要有和没有的区分,多和少的区分就可以了。肿瘤细胞和正常细 : 胞物质代谢有明显差别。PET肿瘤显像早就开始临床应用了。你去搜搜相关文献应该不少 : : but
y*6
6 楼
I read this paper a year ago. I do think this is something interesting. It looks like some tumor cell transporting systems are specific to these fluorescent dyes. PET imaging depends on tumor-specific characterirstics such as higher metabolic rate (FDG probe), or tumor markers. This paper is different in that the fluorescent dyes are supposed to be non-selective. However no mechanism was studied in this paper. Can anyone think of any mechanism? 这个不新鲜。也不一定要有和没有的区分,多和少的区分就可以了。肿瘤细胞和正常细 胞物质代谢有明显差别。PET肿瘤显像早就开始临床应用了。你去搜搜相关文献应该不少
but
【在 m********8 的大作中提到】 : 看到这篇文献的报道,似乎活体内肿瘤细胞和正常细胞吸收不同化学物质的功能差别可 : 能很大。既然如此,在原理上,对肿瘤的诊断并不是医学上的难点? : Clin Cancer Res. 2010 May 15; 16(10): 2833. : Near IR heptamethine cyanine dye-mediated cancer imaging. : Fig1. Active uptake of hepatamethine cyanine dyes by human cancer cells but : not normal cells in cultureClin Cancer Res. 2010 May 15; 16(10): 2833.