Illumina Introduces the HiSeq 2500
Speed and Performance Enhancements Pave the Way to Future Clinical Use
Illumina ILMN +2.61% today introduced the HiSeq(R) 2500, a next-generation
sequencing system that will enable researchers and clinicians to sequence an
entire genome in approximately 24 hours, "Genome in a Day". The HiSeq 2500
leverages the continued technology advancements from both the HiSeq 2000 and
MiSeq(TM) platforms.
"The ability to sequence an entire genome in a day with the same high
quality data as the HiSeq 2000 will enable new opportunities for researchers
to develop medically relevant whole-genome applications," said Jay Flatley,
President and Chief Executive Officer at Illumina. "With the HiSeq 2500,
Illumina is taking another significant step forward in enabling our vision
of revolutionizing human healthcare."
The HiSeq 2500 offers:
-- Unprecedented Speed and Flexibility -- two modes allow researchers to
generate 120 gigabases (Gb) of data in 27 hours, or 600 Gb in a standard
HiSeq run.
-- High Quality Data- system uses the proven SBS chemistry that has made
both the HiSeq 2000 and the MiSeq systems the most accurate next-generation
sequencers.
-- Expanding Applications -- enables researchers to sequence a human genome
or 20 exomes in a day, or 30 RNA sequencing samples in as little as five
hours.
-- Industry Leading Simplicity and Ease-of-Use -- integrated cluster
generation process enables a simplified workflow similar the MiSeq platform.
-- Upgradable from HiSeq 2000 -- through a simple, field-based upgrade
priced at $50,000.
The Company also announced the following performance enhancements to the
MiSeq personal sequencer:
-- Threefold Increase in Throughput -- capable of generating up to 7 Gb per
run, expanding the number of applications and increasing sample throughput.
-- Longer and More Reads -- a new 500-cycle reagent kit supports 2 x 250 bp
runs, generating over 15 million clusters per run and enabling more accurate
small-genome assembly and small RNA sequencing projects.
-- Faster Run Times -- Faster cycle times enable rapid turnaround
applications, allowing researchers to perform microbial identification
sequencing in as little as 2 1/2 hours.
"The HiSeq 2500 and the improvements to our MiSeq platform continue to
demonstrate the headroom our SBS sequencing chemistry brings to the
evolution of next-generation sequencing," said Flatley. "These improvements
will enable expansion into new markets, moving next-gen sequencing
applications closer to the clinic, and broadening access to labs of all
types around the world."
The Company expects to begin full commercial shipment of the HiSeq 2500 in
the second half of 2012. Upgrades will be available to all HiSeq 2000
customers. MiSeq performance improvements will be available to all new and
existing customers starting mid-2012.
