Postdoc opening at Vanderbilt to study cancer epigenetics - 未名空间MITBBS历史存档

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Postdoc opening at Vanderbilt to study cancer epigenetics

Postdoc opening at Vanderbilt to study cancer epigenetics# Biology - 生物学

b*d2013-06-12 07:06

1 楼

今年农妇没啥好成果汇报，沦落成彻头彻尾的瓜娃子了。香瓜收的吃不动到处送人。
黄瓜叶子都黄了，光杆司令果实还不断。，凉拌，呛锅，红烧，各种方法尝遍了都快吃
腻了，还有几十根挂藤上。还送了很多给老美同事，同事都特喜欢，强烈要求吃不完
扔过去。
扁豆一个星期可以收2大盘。切丝+辣椒肉丝清炒永远是老公带饭的最爱。就是每次pick
up和处理扁豆时那个味道太重了，洗不掉。搞得只好带手套操作.农友们有啥好建议去
掉手上那种青涩味道?
最大的收获，上周末在临近的一个小店买到了我魂牵梦绕的chick poo......哈哈。那
兴奋喜悦之情真的不是买奢侈品可以beat的，突然觉得自己真的退化成不要红妆要鸡汤
的农妇啦！很祥林嫂的见邻居朋友就念叨买到传说中的鸡汤。搞得几个朋友跑来家里要
秋拨的种子和鸡汤sample看疗效。 .
秋季展望:
秋播本来早该做，迟迟没有动力。
有了鸡汤感觉底气十足。前几天翻出alou寄来的种子和家里剩下的存货。撒了红菜苔，
黄心无和某种小白菜。555555555可今天都三天了还没着影子! 天灵灵地灵灵保佑我的
小苗苗都快出来，打霜后可以吃上时蔬。

B*d2013-06-12 07:06

2 楼

We are a small but active lab that centers on translational cancer research.
On the basis of our recent findings in BET bromodomain epigenetic readers,
we decide to expand our study in this emerging field.
Position: We are seeking for independent, ambitious, and self-motivated
candidates for a postdoctoral fellow position to study the epigenetic
mechanisms in cancer. The main goal of our laboratory is to develop
innovative diagnostic and therapeutic strategies for glioma and other brain
cancers.
Responsibility: On the basis of our prior studies, the candidate will lead
projects focused on the BET bromodomain proteins and other epigenetic
regulators in glioma. The project will apply molecular, cellular, and
bioinformatics tools as well as animal models to develop new epigenetic
therapy and design rational drug combinations. There will be ample
opportunities to collaborate with other investigators.
Qualifications: The candidate is expected to have his/her doctoral degree
awarded no more than 5 years ago in a biomedical research-related discipline
, and demonstrate a proven track record of high-quality scientific research,
as evidenced by publication record and letters of recommendation.
Experience in epigenetics, cancer genetics and data mining would be
preferred.
Application: Interested applicants should send a cover letter explaining
their research interest and career goals, an updated CV, and contact details
for 2 or more referees to j***********[email protected] Successful
candidate will receive salary and benefits commensurate with prior
experience and qualifications.

h*e2013-06-12 07:06

3 楼

那个青涩味不是比香水更好闻？

pick

【在 b*****d 的大作中提到】

: 今年农妇没啥好成果汇报，沦落成彻头彻尾的瓜娃子了。香瓜收的吃不动到处送人。
: 黄瓜叶子都黄了，光杆司令果实还不断。，凉拌，呛锅，红烧，各种方法尝遍了都快吃
: 腻了，还有几十根挂藤上。还送了很多给老美同事，同事都特喜欢，强烈要求吃不完
: 扔过去。
: 扁豆一个星期可以收2大盘。切丝+辣椒肉丝清炒永远是老公带饭的最爱。就是每次pick
: up和处理扁豆时那个味道太重了，洗不掉。搞得只好带手套操作.农友们有啥好建议去
: 掉手上那种青涩味道?
: 最大的收获，上周末在临近的一个小店买到了我魂牵梦绕的chick poo......哈哈。那
: 兴奋喜悦之情真的不是买奢侈品可以beat的，突然觉得自己真的退化成不要红妆要鸡汤
: 的农妇啦！很祥林嫂的见邻居朋友就念叨买到传说中的鸡汤。搞得几个朋友跑来家里要

c*e2013-06-12 07:06

4 楼

Just looked at his cancer cell paper about LZAP, which only represent
0.3% of mutation. The mRNA level is more correlated with copy number,
a significant portion of the patients gained more copies and express
higher level of LZAP.
He claimed "protein levels were markedly decreased in 32% of primary HNSCCs
(n = 28)".
I do not know him, but I am curious why this will be the research target.

b*d2013-06-12 07:06

5 楼

。。。。。。看来还需要再修炼几层。。才能达到辣总那个境界

【在 h******e 的大作中提到】

: 那个青涩味不是比香水更好闻？
:
: pick

w*r2013-06-12 07:06

6 楼

0.3% is a lot

HNSCCs

【在 c********e 的大作中提到】

: Just looked at his cancer cell paper about LZAP, which only represent
: 0.3% of mutation. The mRNA level is more correlated with copy number,
: a significant portion of the patients gained more copies and express
: higher level of LZAP.
: He claimed "protein levels were markedly decreased in 32% of primary HNSCCs
: (n = 28)".
: I do not know him, but I am curious why this will be the research target.

h*e2013-06-12 07:06

7 楼

chicken poop都用上了，那个境界很快到了

【在 b*****d 的大作中提到】

: 。。。。。。看来还需要再修炼几层。。才能达到辣总那个境界

c*e2013-06-12 07:06

8 楼

That means 3 individual in 1000 patients.
one has deletion.
one has two copies.
one has splice problem.
Is this a lot?

【在 w*****r 的大作中提到】

: 0.3% is a lot
:
: HNSCCs

f*c2013-06-12 07:06

9 楼

同没觉得青涩味难闻哈

B*d2013-06-12 07:06

10 楼

That was my PhD work years ago. My group focuses on glioblastoma.
It is interesting that you carefully read the old paper and checked TCGA
data, which was not available back 2006. Changes at DNA levels and protein
levels are not necessarily correlate. Protein levels are obviously more
relevant to functions.

a*u2013-06-12 07:06

11 楼

空运点香瓜来啊，帮你吃！

【在 b*****d 的大作中提到】

A*y2013-06-12 07:06

12 楼

Congratz on your R01.

【在 B****d 的大作中提到】

: That was my PhD work years ago. My group focuses on glioblastoma.
: It is interesting that you carefully read the old paper and checked TCGA
: data, which was not available back 2006. Changes at DNA levels and protein
: levels are not necessarily correlate. Protein levels are obviously more
: relevant to functions.