Both the Lofgren and Smith bills would bar foreign students earning advanced biology degrees from eligibility for the new visas. U.S. citizens already face stiff competition for jobs in bioscience fields, according to a Republican staffer on the Judiciary Committee. "There is a very high unemployment rate in that sector already. It doesn't make sense to make it any harder for them," says the aide.
Take H1B, it has nothing to do with your pending 485. Also, H1B allows dual intention of immigration/non-immigration. It provides your best protection once your 485 is rejected for any reason.