这算不算打脸？MicroRNAs are digested, not absorbed# Biology - 生物学
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There has been a lot of controversy in recent years over the issue of
whether exogenous microRNA molecules can be absorbed from food and even have
a physiological effect. A new study using mouse models settles the question
by demonstrating that the posited dietary uptake does not take place. This
questions the potentially promising concept of creating functional foods
based on microRNAs.
The scientific world was astonished when, in 2011, Chinese researchers
claimed to have found evidence suggesting that minute fragments of plant
genetic material -- so-called microRNA molecules -- of rice ingested from
food could play a role in regulating physiological processes in the human
body. If this is indeed true, it might even be possible to deliberately
modify human physiological functions via this route, for instance by
incorporating microRNAs into novel functional foods. As a strategy, this
holds considerable potential. For example, certain endogenous microRNA
molecules have been shown to suppress cancer cell growth, and others are
known to be involved in the development of diseases such as obesity and
diabetes.
http://www.sciencedaily.com/releases/2015/09/150908103645.htm
whether exogenous microRNA molecules can be absorbed from food and even have
a physiological effect. A new study using mouse models settles the question
by demonstrating that the posited dietary uptake does not take place. This
questions the potentially promising concept of creating functional foods
based on microRNAs.
The scientific world was astonished when, in 2011, Chinese researchers
claimed to have found evidence suggesting that minute fragments of plant
genetic material -- so-called microRNA molecules -- of rice ingested from
food could play a role in regulating physiological processes in the human
body. If this is indeed true, it might even be possible to deliberately
modify human physiological functions via this route, for instance by
incorporating microRNAs into novel functional foods. As a strategy, this
holds considerable potential. For example, certain endogenous microRNA
molecules have been shown to suppress cancer cell growth, and others are
known to be involved in the development of diseases such as obesity and
diabetes.
http://www.sciencedaily.com/releases/2015/09/150908103645.htm
