2016 Breakthrough Prize in Life Sciences# Biology - 生物学
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2016 Breakthrough Prize in Life Sciences
The Breakthrough Prize in Life Sciences honors transformative advances
toward understanding living systems and extending human life, with one prize
dedicated to work that contributes to the understanding of Parkinson’s
disease and neurodegenerative disorders.
Edward S. Boyden, Massachusetts Institute of Technology: for the development
and implementation of optogenetics – the programming of neurons to express
light-activated ion channels and pumps, so that their electrical activity
can be controlled by light.
Karl Deisseroth, Stanford University and Howard Hughes Medical Institute:
for the development and implementation of optogenetics – the programming of
neurons to express light-activated ion channels and pumps, so that their
electrical activity can be controlled by light.
John Hardy, University College London: for discovering mutations in the
Amyloid Precursor Protein gene (APP) that cause early onset Alzheimer’s
disease, linking accumulation of APP-derived beta-amyloid peptide to
Alzheimer’s pathogenesis and inspiring new strategies for disease
prevention.
Helen Hobbs, University of Texas Southwestern Medical Center and Howard
Hughes Medical Institute: for the discovery of human genetic variants that
alter the levels and distribution of cholesterol and other lipids, inspiring
new approaches to the prevention of cardiovascular and liver disease.
Svante Pääbo, Max Planck Institute for Evolutionary Anthropology:
for pioneering the sequencing of ancient DNA and ancient genomes, thereby
illuminating the origins of modern humans, our relationships to extinct
relatives such as Neanderthals, and the evolution of human populations and
traits.
The Breakthrough Prize in Life Sciences honors transformative advances
toward understanding living systems and extending human life, with one prize
dedicated to work that contributes to the understanding of Parkinson’s
disease and neurodegenerative disorders.
Edward S. Boyden, Massachusetts Institute of Technology: for the development
and implementation of optogenetics – the programming of neurons to express
light-activated ion channels and pumps, so that their electrical activity
can be controlled by light.
Karl Deisseroth, Stanford University and Howard Hughes Medical Institute:
for the development and implementation of optogenetics – the programming of
neurons to express light-activated ion channels and pumps, so that their
electrical activity can be controlled by light.
John Hardy, University College London: for discovering mutations in the
Amyloid Precursor Protein gene (APP) that cause early onset Alzheimer’s
disease, linking accumulation of APP-derived beta-amyloid peptide to
Alzheimer’s pathogenesis and inspiring new strategies for disease
prevention.
Helen Hobbs, University of Texas Southwestern Medical Center and Howard
Hughes Medical Institute: for the discovery of human genetic variants that
alter the levels and distribution of cholesterol and other lipids, inspiring
new approaches to the prevention of cardiovascular and liver disease.
Svante Pääbo, Max Planck Institute for Evolutionary Anthropology:
for pioneering the sequencing of ancient DNA and ancient genomes, thereby
illuminating the origins of modern humans, our relationships to extinct
relatives such as Neanderthals, and the evolution of human populations and
traits.
