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China spurs quest for human variome with $300 million over

China spurs quest for human variome with $300 million over# Biology - 生物学

f*g2011-01-28 08:01

1 楼

前年往fidelity Roth IRA自己开得账户里面存了$4000,没有投资，没有任何收益，所
以去年又都拿了出来，结果IRS说这个也是income，要收income tax外加还有10%
retirement tax,加上interest接近$1500，请问这个合理吗？前年存进去的是自己的钱
，一点收益都没有，去年原封不动拿出来就要被收那么多？请懂的同学帮忙看看是不是
可以argue?
谢谢啦！

y*y2011-01-28 08:01

2 楼

父母上次来的时候申请了Tax ID。这次申请需要填吗？填了会不会有影响？

O*e2011-01-28 08:01

3 楼

有钱啊有钱！
http://www.nature.com/news/2011/110125/full/469455a.html
The Human Variome Project (HVP), an ambitious initiative to uncover all
of the genetic variations that cause human disease, received a massive b
oost last week when China announced that it would commit US$300 million
to the effort. The investment, to be paid out over ten years, puts the p
roject on a firm footing for the first time since its launch in 2006, an
d signals China's intention to take on a bigger role in the medical-gene
tics field.
The sum is meant to cover roughly 25% of the cost of the HVP, a proporti
on matching China's share of the world's population and in keeping with
its growing economic influence, says Ming Qi, director of the Zhejiang U
niversity Center for Genetic and Genomic Medicine, who has led the Chine
se initiative. "With the state of our economic development, I felt we
could do more," adds Qi.
As part of the agreement, announced on 21 January at the project's headq
uarters in Melbourne, Australia, China will set up a genetics institute
in Beijing to coordinate activities across the country and to give train
ing in genetic counselling and testing. "The research will be very close
to the clinic," says Qi. "It will be a fundamental change for China."
The HVP's goal is to establish "the standards, systems and infrastructur
e" that will allow sharing of disease-related genetic data between docto
rs and scientists throughout the world for use in diagnosis and research
. Each participating country will have a network, or 'node', that
collects information from diagnostic testing laboratories and hospitals.
Institutions that have signed up to help develop China's node include Pe
king Union Medical College Hospital, Tianjin Medical University Cancer I
nstitute and Hospital and hospitals affiliated with Zhejiang University
School of Medicine and Peking University. Qi envisages the funding
bringing many more on board.
China's move offers not only financial resources but also greater access
to a vast swathe of human genetic data from a part of the world
previously under-represented in genetic studies. Five other nations are also
developing nodes for the project Australia, Kuwait, Malaysia, Egypt and
Belgium. "We hope the commitment from the Chinese government will also h
ighlight the need for this work to other countries and their funding bod
ies," says Richard Cotton, a geneticist at the University of Melbourne and
head of the project's coordinating office.
Although other projects, such as the International HapMap Project, have
assembled data on single nucleotide polymorphisms common genetic varia
tions across populations the HVP is collecting information on all gene
tic variations related to human disease, including new and rare mutation
s, large-scale deletions and copy number variations. "We're casting our
net wider," says Cotton. "We want to collect every case of each disease.
"

d*n2011-01-28 08:01

4 楼

roth or traditional?

【在 f**g 的大作中提到】

: 前年往fidelity Roth IRA自己开得账户里面存了$4000,没有投资，没有任何收益，所
: 以去年又都拿了出来，结果IRS说这个也是income，要收income tax外加还有10%
: retirement tax,加上interest接近$1500，请问这个合理吗？前年存进去的是自己的钱
: ，一点收益都没有，去年原封不动拿出来就要被收那么多？请懂的同学帮忙看看是不是
: 可以argue?
: 谢谢啦！

z*e2011-01-28 08:01

5 楼

有人回复我，说填了，中信代签的，没问题。
但我还是觉得这东西填了，没有好处，只会说明你会呆很长时间，对面试的可能有不好
影响。我犹豫是不是就不填了。

【在 y*****y 的大作中提到】

: 父母上次来的时候申请了Tax ID。这次申请需要填吗？填了会不会有影响？

i*R2011-01-28 08:01

6 楼

华大不得乐坏了

u*c2011-01-28 08:01

7 楼

Roth 不用

【在 f**g 的大作中提到】

y*y2011-01-28 08:01

8 楼

I think they know how long you stayed before no matter you input this or not.
Of course, they may not find it out if you don't fill in, but what if they
find out.

【在 z****e 的大作中提到】

: 有人回复我，说填了，中信代签的，没问题。
: 但我还是觉得这东西填了，没有好处，只会说明你会呆很长时间，对面试的可能有不好
: 影响。我犹豫是不是就不填了。

g*d2011-01-28 08:01

9 楼

huge!

c*i2011-01-28 08:01

10 楼

去当地的IRS办公室问问，你可能需要补个表。

z*e2011-01-28 08:01

11 楼

I guess it's not a very important information. You may say you don't
remember this number.

not.

【在 y*****y 的大作中提到】

: I think they know how long you stayed before no matter you input this or not.
: Of course, they may not find it out if you don't fill in, but what if they
: find out.

b*r2011-01-28 08:01

12 楼

这个祁明可真是选对时机了啊
其实在美国估计是没恬妞上，98年他就在做AP了现在还是AP，然后NIH的grant一个没拿
到，只有3个co-IP
这一把回去，就是3亿美元的director了
其实我老06年也在尝试和国内搞这类project，只可惜我能找上那几个人太土了，意识
不到这是将来必然的方向
我恨啊……

f*e2011-01-28 08:01

13 楼

roth不用交income tax，但是有一个10% early withdraw penalty是要交的。

【在 f**g 的大作中提到】

S*P2011-01-28 08:01

14 楼

现在回去也不晚，是真金定会发光的

【在 b****r 的大作中提到】

: 这个祁明可真是选对时机了啊
: 其实在美国估计是没恬妞上，98年他就在做AP了现在还是AP，然后NIH的grant一个没拿
: 到，只有3个co-IP
: 这一把回去，就是3亿美元的director了
: 其实我老06年也在尝试和国内搞这类project，只可惜我能找上那几个人太土了，意识
: 不到这是将来必然的方向
: 我恨啊……

u*c2011-01-28 08:01

15 楼

no. Roth本金部分可以随时提取，不需要交10%

【在 f*****e 的大作中提到】

: roth不用交income tax，但是有一个10% early withdraw penalty是要交的。

w*y2011-01-28 08:01

16 楼

天朝这项巨额科研投资看起来还不错
就是不知道实施起来能不能有实力做出一批有用的好数据了

【在 O******e 的大作中提到】

: 有钱啊有钱！
: http://www.nature.com/news/2011/110125/full/469455a.html
: The Human Variome Project (HVP), an ambitious initiative to uncover all
: of the genetic variations that cause human disease, received a massive b
: oost last week when China announced that it would commit US$300 million
: to the effort. The investment, to be paid out over ten years, puts the p
: roject on a firm footing for the first time since its launch in 2006, an
: d signals China's intention to take on a bigger role in the medical-gene
: tics field.
: The sum is meant to cover roughly 25% of the cost of the HVP, a proporti

d*n2011-01-28 08:01

17 楼

wrong, that's only for capital gain or interest.

【在 f*****e 的大作中提到】

: roth不用交income tax，但是有一个10% early withdraw penalty是要交的。

b*r2011-01-28 08:01

18 楼

金子一埋几亿年也没事啊

【在 S*****P 的大作中提到】

: 现在回去也不晚，是真金定会发光的

f*g2011-01-28 08:01

19 楼

是Roth IRA，$4000全是本金，不过是前一年放进去，去年原封不动拿出来的。
我是听说Roth IRA不用交tax，因为存进去的本来就是税后的工资，而且Roth IRA随时
可以拿出来，才这么做的，没想到IRS的信里面说收到fidelity 的1099-R form说我去
年拿了retirement account $4000,让我补交25% income tax+10%。还说如果不同意也
可以argue。既然大家确认了不用交，那我就要跟他们argue了。

【在 f**g 的大作中提到】

M*n2011-01-28 08:01

20 楼

说明在中国还是民工吃香。
这种data攒在那里，啥时候有用很难说。
如果公开的话，得益的是美国和其他国家的科研。

s*d2011-01-28 08:01

21 楼

不用交。
去 local office 吧

m*p2011-01-28 08:01

22 楼

I am wondering the sample size, and what criteria will be to choose the
samples. Lets discuss that, if interested in.