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what do you think?# Biology - 生物学
t*g
1
我的PD是09年5月,现在该预约体检了吗?
还有,485递交上去,一般多久会有消息啊?
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f*w
2
staples 的coupon可以用来买kindle么?
有包子
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z*a
3
One "neuron" paper published 5 years ago from group I showed that knockout of A produced B as the major
results of the paper.
I have just read a "journal of neuroscience" article from group II demonstrated that knockout of A did not
produce B. And the PI of group I is one of the co-authors.
The neuron paper is not retracted. And it seems nobody cares about why the wrong results published in Neuron
in the first place.
I am wondering how the so-called self-correction works in academic world. please share you opinions.
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a*x
4
体检不着急。没办出生公证的先办公证。

【在 t****g 的大作中提到】
: 我的PD是09年5月,现在该预约体检了吗?
: 还有,485递交上去,一般多久会有消息啊?

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P*a
5
嘛酷胖?

【在 f********w 的大作中提到】
: staples 的coupon可以用来买kindle么?
: 有包子

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z*h
6
Self correction takes a long time. For new comers, they have to suffer from
wrong information. No one retracts wrong papers from most journals, except
CNS papers.
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f*w
7
25 off 100 或25 off 100的
有没有可以用在kindle 上的coupon?

【在 P***a 的大作中提到】
: 嘛酷胖?
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D*a
8
Self correction不是这个人him/herself correction啊
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P*a
9
记得不行

【在 f********w 的大作中提到】
: 25 off 100 或25 off 100的
: 有没有可以用在kindle 上的coupon?

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s*y
10
只要第一篇文章不涉及作假,一般是不会被撤掉的。
因为科学里面很多实验结果是很复杂的。第一篇文章可能是没有考虑到一些
额外的原因,或者没有找到正确的条件。

of A produced B as the major
demonstrated that knockout of A did not
wrong results published in Neuron
please share you opinions.

【在 z*******a 的大作中提到】
: One "neuron" paper published 5 years ago from group I showed that knockout of A produced B as the major
: results of the paper.
: I have just read a "journal of neuroscience" article from group II demonstrated that knockout of A did not
: produce B. And the PI of group I is one of the co-authors.
: The neuron paper is not retracted. And it seems nobody cares about why the wrong results published in Neuron
: in the first place.
: I am wondering how the so-called self-correction works in academic world. please share you opinions.

avatar
f*w
11
包子发了,请查收。
多谢解疑。

【在 P***a 的大作中提到】
: 记得不行
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o*r
12
除非他们用完全相同的条件做实验得出相反的结果。生物很多东西都不是绝对的,比如
tamoxifen对某些breast cancer cell是antagonist,对另一些是agonist,效果取决于
实验设计。

of A produced B as the major
demonstrated that knockout of A did not
wrong results published in Neuron
please share you opinions.

【在 z*******a 的大作中提到】
: One "neuron" paper published 5 years ago from group I showed that knockout of A produced B as the major
: results of the paper.
: I have just read a "journal of neuroscience" article from group II demonstrated that knockout of A did not
: produce B. And the PI of group I is one of the co-authors.
: The neuron paper is not retracted. And it seems nobody cares about why the wrong results published in Neuron
: in the first place.
: I am wondering how the so-called self-correction works in academic world. please share you opinions.

avatar
l*a
13
个人觉得,除非影响力很大的paper,一般只要不是造假就不会retract。有时候只能说
第一篇的分
析不太careful,或者实验design不好导致了wrong interpretation。

knockout of A produced B as the major
demonstrated that knockout of A did not
the wrong results published in Neuron
world. please share you opinions.

【在 z*******a 的大作中提到】
: One "neuron" paper published 5 years ago from group I showed that knockout of A produced B as the major
: results of the paper.
: I have just read a "journal of neuroscience" article from group II demonstrated that knockout of A did not
: produce B. And the PI of group I is one of the co-authors.
: The neuron paper is not retracted. And it seems nobody cares about why the wrong results published in Neuron
: in the first place.
: I am wondering how the so-called self-correction works in academic world. please share you opinions.

avatar
h*u
14

knockout of A produced B as the major
demonstrated that knockout of A did not
the wrong results published in Neuron
world. please share you opinions.
welcome to biomedical science. this is VERY typical. take it with a
grain of salt.

【在 z*******a 的大作中提到】
: One "neuron" paper published 5 years ago from group I showed that knockout of A produced B as the major
: results of the paper.
: I have just read a "journal of neuroscience" article from group II demonstrated that knockout of A did not
: produce B. And the PI of group I is one of the co-authors.
: The neuron paper is not retracted. And it seems nobody cares about why the wrong results published in Neuron
: in the first place.
: I am wondering how the so-called self-correction works in academic world. please share you opinions.

avatar
f*n
15
感觉怎么都行,怎么都算对,不能产业化,和人民群众生活没有联系。
几个在那里自爽的大牛,养这一群包身工奴隶。
这就是生物的现状。
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z*a
16
I guess I know what you meant.
But these two papers used exact the same genetic manipulation and assayed
well established fly behavior. The
assay itself is as easy as counting to three.
The only caveat could be genetic manipulations. But both papers utilized
multiple genetic tools to knock out a
gene of interest or kill several neurons that expressing the gene.
I was thinking results from well established behavior assay should be
somehow less variable than biochemical
assay between different people and betwn labs.

【在 o********r 的大作中提到】
: 除非他们用完全相同的条件做实验得出相反的结果。生物很多东西都不是绝对的,比如
: tamoxifen对某些breast cancer cell是antagonist,对另一些是agonist,效果取决于
: 实验设计。
:
: of A produced B as the major
: demonstrated that knockout of A did not
: wrong results published in Neuron
: please share you opinions.

avatar
s*y
17
这种文章怎么说呢?科学界就是充满争议的。
不过第一篇文章的作者也在第二篇里出现,那就是比较奇怪的事情了,
有点像自己挖了个坑自己填的感觉。
估计要等第三个实验室去重复才能知道到底怎么回事了。

【在 z*******a 的大作中提到】
: I guess I know what you meant.
: But these two papers used exact the same genetic manipulation and assayed
: well established fly behavior. The
: assay itself is as easy as counting to three.
: The only caveat could be genetic manipulations. But both papers utilized
: multiple genetic tools to knock out a
: gene of interest or kill several neurons that expressing the gene.
: I was thinking results from well established behavior assay should be
: somehow less variable than biochemical
: assay between different people and betwn labs.

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