amazing new gene expression switch# Biology - 生物学
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Peter Quail's group from Berkley employs light-wavelength sensitive proteins
(phytochrome) to obtain a potential light switched gene expression tool.
In plants, phytochromes exist in 2 states: Pr (sensitive to red light and turn
into Pfr), Pfr (receive far red light and turn into Pr). Only Pfr can bind to
a protein called PIF3.
Now they hook one half of GAL4 to phytochrome, another half to PIF3. Thus only
certain light could cause Pfr binding with PIF3, therefore bring together 2
halves of GAL4,
(phytochrome) to obtain a potential light switched gene expression tool.
In plants, phytochromes exist in 2 states: Pr (sensitive to red light and turn
into Pfr), Pfr (receive far red light and turn into Pr). Only Pfr can bind to
a protein called PIF3.
Now they hook one half of GAL4 to phytochrome, another half to PIF3. Thus only
certain light could cause Pfr binding with PIF3, therefore bring together 2
halves of GAL4,