3D打印机做的人体器官和肿瘤# LeisureTime - 读书听歌看电影
wh
1 楼
看到耶鲁校报上登了一幅耶鲁工程实验室用三维打印机做出来的膝盖和肿瘤，是塑料的
，用来给医生和病人看/摸肿瘤的大小形状和位置：
（A Yale physician has begun using the 3D printers at Yale's Center for
Engineering and Innovation Design to make 3D organs — precise replicas of
actual patients' organs. Here, a knee with tumor. Image by Yale CEID)
三维打印机花了24小时做这个。负责人说希望技术成熟后打印更方便快速，对外科手术
会帮助很大，也让病人确切知道病情和治疗进展——亲眼看/亲手摸到肿瘤渐渐变小，
hopefully。lateleo上次说的用三维打印机做出来的心脏组织是真的人体器官组织是吗
？那是不是显得这个小儿科啊……那个蓝球当中的红点是啥？
附新闻链接：
http://news.yale.edu/2013/07/15/dr-mark-michalski-ready-print-3
Dr. Mark Michalski is ready to print a 3-D brain (maybe yours)
By Eric Gershon
July 15, 2013
In a year’s time, the 3-D printers at Yale’s Center for Engineering
Innovation and Design (CEID) have churned out countless parts, prototypes,
and curiosity-driven experiments in plastic — rotorheads and racecar
uprights, cardiac pump pieces and thermostats, snowmen, keychains, and
fantastical geometric shapes.
Radiology resident Dr. Mark Michalski uses them to print organs — arteries
and bones, a liver, a heart, a knee.
“The next step will be a brain,” he said.
These “printouts” are not mere curiosities. They’re precise three-
dimensional replicas of the idiosyncratic, usually diseased, anatomy of
specific human patients — unique models that can be helpful to medical
students, clinicians, and, Michalski hopes, patients trying to understand
what’s happening inside their bodies.
“We can create things that will change the practice of medicine,” he said.
Ultimately, Michalski hopes to produce series of 3D anatomical printouts
showing the progress of patients’ treatment — a way of communicating that
he believes might also help them endure the unpleasant aspects of healing.
“If we can demonstrate the way that a tumor has changed with treatment,
then we can help patients understand that all the nausea and vomiting wasn’
t for naught,” he said of these theoretical cancer patients. “We can say,
‘It reduced the tumor — and I can show you exactly how much.’ Patients
could wrap their palms around exact replicas of their own tumors at various
stages of shrinkage.”
The August 2012 opening of the CEID, a design studio on Prospect Street that
is part of the School of Engineering & Applied Science, has made Yale a
more versatile place for experimenters like Michalski by providing both
resources and organizational support for skilled but low-key invention —
tools, materials, personnel, and space.
“Before the CEID there was no avenue for this at Yale,” said Joseph Zinter
, the CEID’s assistant director and a lecturer in mechanical engineering
and materials science. “Now, a physician at the medical school can say, ‘I
have this idea and I’ll go to the CEID to explore it.’ We can help turn a
good idea into a physical innovation, a real, tangible thing, and often
very fast.”
Among the center’s resources are five 3-D printers, a technology for rapid
automated fabrication, usually with plastics. The printers are available to
all students, faculty, and research staff who become CEID members. Nearly 1,
000 have done so already, representing nearly every school at Yale. Last
fall, Michalski, a fourth-year radiology resident and Holman Research Fellow
, was one of them.
He knew of attempts elsewhere to produce model anatomical organs with 3-D
printers, as well as surgical implants, and thought he’d like to try. He
was driven partly by curiosity, he said, and partly by an interest in
developing new tools for patient communication.
Working in his spare time, Michalski began with a liver, then moved on to a
liver with embedded tumor. One day Zinter noticed Michalski’s hospital
badge and, excited by a physician’s presence at the CEID, asked what he was
working on. “Lung vessels,” Michalski told him, and a partnership was
born. “‘You have our full attention,’” Zinter told him. “‘We will
support you in every way.’”
“For us,” Zinter said later, “this was a natural bridge to the medical
community, to influencing patient outcomes.”
Michalski eventually showed a replica of a child’s heart, with anatomical
defects, to a group of pediatric cardiologists. “One of them said, ‘Wow,
you can do that?’ And they immediately started talking about ways they
could use it to plan non-invasive, catheter-based inventions,” Michalski
said. “That’s what got me thinking this could also be a service we could
provide clinicians.”
In early June, he and Zinter got the chance. A colleague told Michalski that
Dr. Dieter Lindskog, an orthopedic surgeon at Yale, was preparing for a
complicated surgery on a man’s knee and the large tumor growing in it.
Lindskog liked the idea of having a 3D model of what he would ultimately see
inside. But he would need it soon.
“We had nine days,” said Michalski. “We wanted this to be exact, as close
, as true to anatomical detail as possible. Potentially, medical decisions
would be made using it.”
Michalski began with MRI images of the knee, using specialized software to
convert them into data the 3D printers could interpret. He delivered the
data files to Zinter and Yusuf Chauhan, a full-time design intern in the
CEID, who managed the fabrication process.
“We ran the machine for 24 hours,” Zinter said.
The final product was a lightweight, plastic 1:1 scale model of the knee —
including femur, fibula, tibia, patella, tendon, and the tumor.
Normally Lindskog would prepare for the operation using two-dimensional,
cross-sectional imaging and extrapolate the tumor’s exact location, he said.
“The 3D model allowed me to see and feel the actual tumor location in the
bone and helped me plan the cuts to remove it,” he said. “When the
technology allows faster printing this will have very broad applications for
surgical planning.”
Zinter and the CEID staff are already at work on other projects with uses in
medicine, including a customized iPhone case that can accommodate a
portable laryngoscope. It’s intended to help physicians working outside a
fully equipped medical facility — in a field clinic, for example — shoot,
save, and transmit video of laryngoscope examinations.
Michalski said he’s ready to move on to a brain. He’s just searching for
the right one.
，用来给医生和病人看/摸肿瘤的大小形状和位置：
（A Yale physician has begun using the 3D printers at Yale's Center for
Engineering and Innovation Design to make 3D organs — precise replicas of
actual patients' organs. Here, a knee with tumor. Image by Yale CEID)
三维打印机花了24小时做这个。负责人说希望技术成熟后打印更方便快速，对外科手术
会帮助很大，也让病人确切知道病情和治疗进展——亲眼看/亲手摸到肿瘤渐渐变小，
hopefully。lateleo上次说的用三维打印机做出来的心脏组织是真的人体器官组织是吗
？那是不是显得这个小儿科啊……那个蓝球当中的红点是啥？
附新闻链接：
http://news.yale.edu/2013/07/15/dr-mark-michalski-ready-print-3
Dr. Mark Michalski is ready to print a 3-D brain (maybe yours)
By Eric Gershon
July 15, 2013
In a year’s time, the 3-D printers at Yale’s Center for Engineering
Innovation and Design (CEID) have churned out countless parts, prototypes,
and curiosity-driven experiments in plastic — rotorheads and racecar
uprights, cardiac pump pieces and thermostats, snowmen, keychains, and
fantastical geometric shapes.
Radiology resident Dr. Mark Michalski uses them to print organs — arteries
and bones, a liver, a heart, a knee.
“The next step will be a brain,” he said.
These “printouts” are not mere curiosities. They’re precise three-
dimensional replicas of the idiosyncratic, usually diseased, anatomy of
specific human patients — unique models that can be helpful to medical
students, clinicians, and, Michalski hopes, patients trying to understand
what’s happening inside their bodies.
“We can create things that will change the practice of medicine,” he said.
Ultimately, Michalski hopes to produce series of 3D anatomical printouts
showing the progress of patients’ treatment — a way of communicating that
he believes might also help them endure the unpleasant aspects of healing.
“If we can demonstrate the way that a tumor has changed with treatment,
then we can help patients understand that all the nausea and vomiting wasn’
t for naught,” he said of these theoretical cancer patients. “We can say,
‘It reduced the tumor — and I can show you exactly how much.’ Patients
could wrap their palms around exact replicas of their own tumors at various
stages of shrinkage.”
The August 2012 opening of the CEID, a design studio on Prospect Street that
is part of the School of Engineering & Applied Science, has made Yale a
more versatile place for experimenters like Michalski by providing both
resources and organizational support for skilled but low-key invention —
tools, materials, personnel, and space.
“Before the CEID there was no avenue for this at Yale,” said Joseph Zinter
, the CEID’s assistant director and a lecturer in mechanical engineering
and materials science. “Now, a physician at the medical school can say, ‘I
have this idea and I’ll go to the CEID to explore it.’ We can help turn a
good idea into a physical innovation, a real, tangible thing, and often
very fast.”
Among the center’s resources are five 3-D printers, a technology for rapid
automated fabrication, usually with plastics. The printers are available to
all students, faculty, and research staff who become CEID members. Nearly 1,
000 have done so already, representing nearly every school at Yale. Last
fall, Michalski, a fourth-year radiology resident and Holman Research Fellow
, was one of them.
He knew of attempts elsewhere to produce model anatomical organs with 3-D
printers, as well as surgical implants, and thought he’d like to try. He
was driven partly by curiosity, he said, and partly by an interest in
developing new tools for patient communication.
Working in his spare time, Michalski began with a liver, then moved on to a
liver with embedded tumor. One day Zinter noticed Michalski’s hospital
badge and, excited by a physician’s presence at the CEID, asked what he was
working on. “Lung vessels,” Michalski told him, and a partnership was
born. “‘You have our full attention,’” Zinter told him. “‘We will
support you in every way.’”
“For us,” Zinter said later, “this was a natural bridge to the medical
community, to influencing patient outcomes.”
Michalski eventually showed a replica of a child’s heart, with anatomical
defects, to a group of pediatric cardiologists. “One of them said, ‘Wow,
you can do that?’ And they immediately started talking about ways they
could use it to plan non-invasive, catheter-based inventions,” Michalski
said. “That’s what got me thinking this could also be a service we could
provide clinicians.”
In early June, he and Zinter got the chance. A colleague told Michalski that
Dr. Dieter Lindskog, an orthopedic surgeon at Yale, was preparing for a
complicated surgery on a man’s knee and the large tumor growing in it.
Lindskog liked the idea of having a 3D model of what he would ultimately see
inside. But he would need it soon.
“We had nine days,” said Michalski. “We wanted this to be exact, as close
, as true to anatomical detail as possible. Potentially, medical decisions
would be made using it.”
Michalski began with MRI images of the knee, using specialized software to
convert them into data the 3D printers could interpret. He delivered the
data files to Zinter and Yusuf Chauhan, a full-time design intern in the
CEID, who managed the fabrication process.
“We ran the machine for 24 hours,” Zinter said.
The final product was a lightweight, plastic 1:1 scale model of the knee —
including femur, fibula, tibia, patella, tendon, and the tumor.
Normally Lindskog would prepare for the operation using two-dimensional,
cross-sectional imaging and extrapolate the tumor’s exact location, he said.
“The 3D model allowed me to see and feel the actual tumor location in the
bone and helped me plan the cuts to remove it,” he said. “When the
technology allows faster printing this will have very broad applications for
surgical planning.”
Zinter and the CEID staff are already at work on other projects with uses in
medicine, including a customized iPhone case that can accommodate a
portable laryngoscope. It’s intended to help physicians working outside a
fully equipped medical facility — in a field clinic, for example — shoot,
save, and transmit video of laryngoscope examinations.
Michalski said he’s ready to move on to a brain. He’s just searching for
the right one.
