LZ is asking about whether he can win the bid using 25% down, not whether he can get mortgage. The answer is yes and no. Yes you can't win the bid if others bid with 40% down while all other things keep equal. No you can win the bid if you bid with higher price and/or better credit and/or mortgage contingency money has time value so sell would always prefer buyer with more down payment but you can still win via other advantages.