g*0
3 楼
啥时候开除Amy?
i*i
5 楼
This article has been retracted at the request of the authors. Donmez et al.
(2010) reported that SIRT1 suppressed Alzheimer’s disease in a mouse model
by upregulating the ADAM 10 α-secretase gene via coactivation of the
retinoic acid receptor, RARβ. Increased α-secretase bypassed the
processing of APP by the β-secretase, thereby reducing the amyloid burden.
It has come to our attention that several figures in the paper contain
images in which gel lanes were spliced together without appropriate
indication. There are also instances of image duplication. We believe that
these errors do not affect the conclusions of experiments in the paper.
Moreover, the finding that SIRT1 upregulates the ADAM 10 α-secretase in
neurons was reported by Theendakara et al. (Theendakara, V., et al. [2013].
Proc. Natl. Acad. Sci. USA 110, 18303–18308), and the more detailed finding
that SIRT1 and RARβ cooperate in neurons to activate ADAM 10 has also
recently been reported by Lee et al. (Lee, H.R., et al. [2014]. J. Neurosci.
Res. Published online June 5, 2014. http://dx.doi.org/10.1002/jnr23421), thereby supporting our main conclusions. However, the level of care in figure preparation in Donmez et al. falls well below the standard that we expect, and we are therefore retracting the paper. We offer our sincerest apologies to the scientific community for these errors and for any inconvenience they may have caused.
(2010) reported that SIRT1 suppressed Alzheimer’s disease in a mouse model
by upregulating the ADAM 10 α-secretase gene via coactivation of the
retinoic acid receptor, RARβ. Increased α-secretase bypassed the
processing of APP by the β-secretase, thereby reducing the amyloid burden.
It has come to our attention that several figures in the paper contain
images in which gel lanes were spliced together without appropriate
indication. There are also instances of image duplication. We believe that
these errors do not affect the conclusions of experiments in the paper.
Moreover, the finding that SIRT1 upregulates the ADAM 10 α-secretase in
neurons was reported by Theendakara et al. (Theendakara, V., et al. [2013].
Proc. Natl. Acad. Sci. USA 110, 18303–18308), and the more detailed finding
that SIRT1 and RARβ cooperate in neurons to activate ADAM 10 has also
recently been reported by Lee et al. (Lee, H.R., et al. [2014]. J. Neurosci.
Res. Published online June 5, 2014. http://dx.doi.org/10.1002/jnr23421), thereby supporting our main conclusions. However, the level of care in figure preparation in Donmez et al. falls well below the standard that we expect, and we are therefore retracting the paper. We offer our sincerest apologies to the scientific community for these errors and for any inconvenience they may have caused.
i*i
6 楼
拉上的这帮跟风的paper,有种临死还要拉几个垫背的赶脚。
是不是这几篇也要撤稿呢?
200多次引用呢。。。。。。大牛害死人啊。。。。
是不是这几篇也要撤稿呢?
200多次引用呢。。。。。。大牛害死人啊。。。。
U*n
9 楼
这个学科的全部问题就是条带贴错了的问题
al.
model
.
【在 i*****i 的大作中提到】
: This article has been retracted at the request of the authors. Donmez et al.
: (2010) reported that SIRT1 suppressed Alzheimer’s disease in a mouse model
: by upregulating the ADAM 10 α-secretase gene via coactivation of the
: retinoic acid receptor, RARβ. Increased α-secretase bypassed the
: processing of APP by the β-secretase, thereby reducing the amyloid burden.
: It has come to our attention that several figures in the paper contain
: images in which gel lanes were spliced together without appropriate
: indication. There are also instances of image duplication. We believe that
: these errors do not affect the conclusions of experiments in the paper.
: Moreover, the finding that SIRT1 upregulates the ADAM 10 α-secretase in
al.
model
.
【在 i*****i 的大作中提到】
: This article has been retracted at the request of the authors. Donmez et al.
: (2010) reported that SIRT1 suppressed Alzheimer’s disease in a mouse model
: by upregulating the ADAM 10 α-secretase gene via coactivation of the
: retinoic acid receptor, RARβ. Increased α-secretase bypassed the
: processing of APP by the β-secretase, thereby reducing the amyloid burden.
: It has come to our attention that several figures in the paper contain
: images in which gel lanes were spliced together without appropriate
: indication. There are also instances of image duplication. We believe that
: these errors do not affect the conclusions of experiments in the paper.
: Moreover, the finding that SIRT1 upregulates the ADAM 10 α-secretase in
a*n
10 楼
可撸
【在 U*******n 的大作中提到】
: http://retractionwatch.com/category/gizem-donmez/
: 保不住她了。
【在 U*******n 的大作中提到】
: http://retractionwatch.com/category/gizem-donmez/
: 保不住她了。
i*a
11 楼
al.
model
.
这种话也有人信?真的不影响结论最多发个erratum,如果retract了一般是重大问题。
干这行的人脸皮一定要厚到一定程度才行。
【在 i*****i 的大作中提到】
: This article has been retracted at the request of the authors. Donmez et al.
: (2010) reported that SIRT1 suppressed Alzheimer’s disease in a mouse model
: by upregulating the ADAM 10 α-secretase gene via coactivation of the
: retinoic acid receptor, RARβ. Increased α-secretase bypassed the
: processing of APP by the β-secretase, thereby reducing the amyloid burden.
: It has come to our attention that several figures in the paper contain
: images in which gel lanes were spliced together without appropriate
: indication. There are also instances of image duplication. We believe that
: these errors do not affect the conclusions of experiments in the paper.
: Moreover, the finding that SIRT1 upregulates the ADAM 10 α-secretase in
v*a
13 楼
美女嘛,看起来不错。
f*b
14 楼
太黑了。什么世道啊。
【在 U*******n 的大作中提到】
: http://retractionwatch.com/category/gizem-donmez/
: 保不住她了。
【在 U*******n 的大作中提到】
: http://retractionwatch.com/category/gizem-donmez/
: 保不住她了。
U*m
18 楼
Leonard Guarante 实验室有多少文章retracted, 又有多少文章被质疑?
MIT就不在乎学校名声的么?
MIT就不在乎学校名声的么?
H*e
21 楼
I do care about HMS but not MIT and UCSD...At least, David Sinclair, Amy
Wagner, Carla Kim, and the BWH one finding stem cells in all organs. Anyone
in HMS can tell something wrong with these guys. Cannot understand why HMS
not finding a chance to remove them!
【在 U******m 的大作中提到】
: someone wrote on retractionwatch that "They should give David Sinclair and
: Lenny Guarente no NIH funds fof 3-4 years. That’ll teach everyone!"
: guess the same should apply to Michael Karin too.
Wagner, Carla Kim, and the BWH one finding stem cells in all organs. Anyone
in HMS can tell something wrong with these guys. Cannot understand why HMS
not finding a chance to remove them!
【在 U******m 的大作中提到】
: someone wrote on retractionwatch that "They should give David Sinclair and
: Lenny Guarente no NIH funds fof 3-4 years. That’ll teach everyone!"
: guess the same should apply to Michael Karin too.
h*l
22 楼
Amy is not at HMS. and Harvard hospitals are all independent
Anyone
HMS
【在 H*****e 的大作中提到】
: I do care about HMS but not MIT and UCSD...At least, David Sinclair, Amy
: Wagner, Carla Kim, and the BWH one finding stem cells in all organs. Anyone
: in HMS can tell something wrong with these guys. Cannot understand why HMS
: not finding a chance to remove them!
Anyone
HMS
【在 H*****e 的大作中提到】
: I do care about HMS but not MIT and UCSD...At least, David Sinclair, Amy
: Wagner, Carla Kim, and the BWH one finding stem cells in all organs. Anyone
: in HMS can tell something wrong with these guys. Cannot understand why HMS
: not finding a chance to remove them!
s*j
24 楼
没开除, 自己不干回土耳其了.
【在 U*******n 的大作中提到】
: http://retractionwatch.com/category/gizem-donmez/
: 保不住她了。
【在 U*******n 的大作中提到】
: http://retractionwatch.com/category/gizem-donmez/
: 保不住她了。
A*y
26 楼
There are always scientists holding human progression back for their own
personal gain.
personal gain.
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