[1]Zhu X, Shen J, Feng S, Huang C, Wang H, Huo F, Liu H. Akkermansia muciniphila, which is enriched in the gut microbiota by metformin, improves cognitive function in aged mice by reducing the proinflammatory cytokine interleukin-6. Microbiome. 2023 May 30;11(1):120. doi: 10.1186/s40168-023-01567-1. PMID: 37254162; PMCID: PMC10228018.[2]Huang X, Sun T, Wang J, Hong X, Chen H, Yan T, Zhou C, Sun D, Yang C, Yu T, Su W, Du W, Xiong H. Metformin reprograms tryptophan metabolism to stimulate CD8+ T cell function in colorectal cancer. Cancer Res. 2023 May 17:CAN-22-3042. doi: 10.1158/0008-5472.CAN-22-3042. Epub ahead of print. PMID: 37195082.[3]Marra PS, Yamanashi T, Crutchley KJ, Wahba NE, Anderson ZM, Modukuri M, Chang G, Tran T, Iwata M, Cho HR, Shinozaki G. Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity. Aging (Albany NY). 2023 Feb 2;15(3):601-616. doi: 10.18632/aging.204498. Epub 2023 Feb 2. PMID: 36734879; PMCID: PMC9970305. 撰文 | Swagpp编辑 | Swagpp来源 | 梅斯医学 活动推荐 精彩推荐: