我们家每个人都轮流一遍几乎和楼主相似的症状,两三个月才好了。 几经检查,最后确诊是一个很陌生之前没听过的病毒: 腺病毒感染。
songsyua 发表于 2023-05-01 13:38
这个病毒英文是 adenovirus J&J was adenovirus. It was considered a DNA vaccine. 这里有篇文章https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061321/ Adenovirus particles can be engineered to display exogenous peptides on their surfaces by modification of viral capsid proteins, and particles that display pathogen-derived peptides can induce protective immunity. We constructed viable recombinant adenoviruses that display B-cell epitopes from the Plasmodium falciparumcircumsporozoite protein (PfCSP) in the major adenovirus capsid protein, hexon. Recombinants induced high-titer antibodies against CSP when injected intraperitoneally into mice. Serum obtained from immunized mice recognized both recombinant PfCSP protein and P. falciparum sporozoites, and neutralized P. falciparum sporozoites in vitro. Replicating adenovirus vaccines have provided economical protection against adenovirus disease for over three decades. The recombinants described here may provide a path to an affordable malaria vaccine in the developing world.