目前,尚无相关专家共识表明哪种通气装置对全身麻醉更有效。本文献复习和Meta分析比较喉罩气道和气管内插管对全身麻醉期间气道并发症的影响。关键词'喉罩气道'、'气管内导管'、'气管导管'、'儿童'、'儿科'、'麻醉'、'随机对照试验'(randomized controlled trials, RCTs)和'随机'在PubMed中进行文献检索。质量评估由两名评价员根据Cochrane协作网工具定义的领域进行。使用Cochrane工具进行资料提取、偏倚风险评估和证据质量评估。共纳入16项随机对照试验。结果表明,喉罩气道组对心率变异性的影响[平均差=-13.76;95%CI,-18.19-(-9.33);P<0.00001],低氧血症的发生率[比值比(OR)=0.52;95%CI,0.28-0.97;P=0.04]和术后咳嗽发生率(OR=0.22;95%CI,0.12-0.40;P<0.0001)明显低于气管插管组。喉罩气道组一次性置入成功率明显高于气管插管组(OR=0.20;95% CI,0.07-0.59;P=0.003)。然而,两组在支气管痉挛、咽痛、黏膜损伤、恶心呕吐和反流吸入方面没有发现显著差异。综上所述,与气管插管相比,喉罩气道应用可减少全身麻醉期间的并发症。关键词:并发症;气管插管;全身麻醉;喉罩气道;荟萃分析。原文摘要Comparison of laryngeal mask airway and endotracheal tube in general anesthesia in childrenAt present, there is no relevant expert consensus indicating which ventilation device is more efficient for general anesthesia. The present literature review and meta-analysis compared the effects of the laryngeal mask airway and endotracheal intubation on airway complications during general anesthesia. The keywords 'laryngeal mask airway', 'endotracheal tube', 'tracheal tube', 'children', 'pediatric', 'anesthesia', 'randomized controlled trials' (RCTs) and 'randomized' were used to perform the literature search in PubMed. Quality assessment was performed by two reviewers according to domains defined by the Cochrane Collaboration tool. Data extraction, risk of bias assessment and quality of evidence assessment were performed with the Cochrane tool. A total of 16 RCTs were included. The results indicated that the effects of the laryngeal mask airway group on heart rate variability [mean difference=-13.76; 95% CI, -18.19-(-9.33); P<0.00001], the incidence of hypoxemia [odds ratio (OR)=0.52; 95% CI, 0.28-0.97; P=0.04] and the incidence of postoperative cough (OR=0.22; 95% CI, 0.12-0.40; P<0.0001) were significantly lower than those of the endotracheal intubation group. The success rate of one-time implantation in the laryngeal mask airway group was significantly higher than that noted in the endotracheal intubation group (OR=0.20; 95% CI, 0.07-0.59; P=0.003). However, no significant differences were noted between the two groups in bronchospasm, sore throat, mucosal injury, nausea and vomiting and reflux aspiration. In conclusion, the results indicated that laryngeal mask airway application can reduce complications during general anesthesia compared with endotracheal intubation.Keywords:complications; endotracheal intubation; general anesthesia; laryngeal mask airway; meta-analysis.