夜间胃内 pH 降低,症状加重,如何处理?
1
NAB 是怎样发生的?
2
不同质子泵抑制剂发生 NAB 的特点
3
治疗 NAB 的临床意义
4
治疗方法
5
注意事项
参考文献:
[1] van Herwaarden, M.A., M. Samsom, and A.J. Smout, Helicobacter pylori eradication increases nocturnal acid breakthrough. Aliment Pharmacol Ther, 2000. 14(7): p. 961-2
[2] Earnest, D L, and M Robinson. 「Treatment advances in acid secretory disorders: the promise of rapid symptom relief with disease resolution.」 The American journal of gastroenterology vol. 94,11 Suppl (1999): S17-24. doi:10.1016/s0002-9270(99)00658-9
[3] Katz, P O et al. 「Review article: acid-related disease--what are the unmet clinical needs?.」 Alimentary pharmacology & therapeutics vol. 23 Suppl 2 (2006): 9-22. doi:10.1111/j.1365-2036.2006.02944.x
[4] Katsube, T., et al., Helicobacter pylori infection influences nocturnal gastric acid breakthrough. Aliment Pharmacol Ther, 2000. 14(8): p. 1049-56
[5] Li, X.Q., et al., Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities. Drug Metab Dispos, 2004. 32(8): p. 821-7
[6] Sachs, G., et al., The pharmacology of the gastric acid pump: the H+,K+ ATPase. Annu Rev Pharmacol Toxicol, 1995. 35: p. 277-305
[7] Adachi, K., et al., Predominant nocturnal acid reflux in patients with Los Angeles grade C and D reflux esophagitis. J Gastroenterol Hepatol, 2001. 16(11): p. 1191-6
[8] Hatlebakk, J.G., et al., Nocturnal gastric acidity and acid breakthrough on different regimens of omeprazole 40 mg daily. Aliment Pharmacol Ther, 1998. 12(12): p. 1235-40
[9] Wang, Y., et al., Additional bedtime H2-receptor antagonist for the control of nocturnal gastric acid breakthrough. Cochrane Database Syst Rev, 2009(4): p. Cd004275
[10] Katz, P.O., et al., ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease. Am J Gastroenterol, 2022. 117(1): p. 27-56
微信扫码关注该文公众号作者